Pre_GI: BLASTP Hits

Some Help

Query: NC_010674:828191:842990 Clostridium botulinum B str. Eklund 17B, complete genome

Start: 842990, End: 843655, Length: 666

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum B str. Eklund 17B is a nonproteolytic botulism neurotoxin B strain. This strain was isolated from marine sediments taken off the coast of Washington, USA and was not associated with botulism. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010723:801215:820206820206820889684Clostridium botulinum E3 str. Alaska E43, complete genomeputative hydrolase5e-90330
NC_020291:4944835:495093449509344951608675Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomehaloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E8e-59226
NC_020210:3169258:318092131809213181625705Geobacillus sp. GHH01, complete genomeHAD-family dehydrogenase1e-44179
NC_014915:3259440:326780632678063268483678Geobacillus sp. Y412MC52 chromosome, complete genomeHaloacid dehalogenase domain protein hydrolase2e-44178
NC_013411:3251500:326183732618373262514678Geobacillus sp. Y412MC61, complete genomeHaloacid dehalogenase domain protein hydrolase2e-44178
NC_014650:376070:391312391312391989678Geobacillus sp. Y4.1MC1 chromosome, complete genomehaloacid dehalogenase3e-39161
NC_012793:3275751:328130832813083282021714Geobacillus sp. WCH70, complete genomeHAD-superfamily hydrolase, subfamily IA, variant 11e-38159
NC_010424:1857062:186450718645071865190684Candidatus Desulforudis audaxviator MP104C, complete genomeHAD-superfamily hydrolase, subfamily IA, variant 11e-35149
NC_007644:779376:790564790564791235672Moorella thermoacetica ATCC 39073, complete genomeHaloacid dehalogenase-like hydrolase4e-35147
NC_015573:1729057:173875717387571739431675Desulfotomaculum kuznetsovii DSM 6115 chromosome, complete genomeHaloacid dehalogenase domain-containing protein hydrolase1e-33143
NC_012881:4055962:406479040647904065476687Desulfovibrio salexigens DSM 2638, complete genomeHAD family hydrolase3e-33141
NC_016112:806256:820852820852821508657Methylomicrobium alcaliphilum chromosome, complete genomehypothetical protein2e-31135
NC_013202:1367447:138920813892081389894687Halomicrobium mukohataei DSM 12286, complete genomeHAD-superfamily hydrolase, subfamily IA, variant 12e-24112
NC_014151:813755:834535834535835245711Cellulomonas flavigena DSM 20109 chromosome, complete genomeHaloacid dehalogenase domain protein hydrolase6e-24110
NC_014220:170021:188850188850189542693Syntrophothermus lipocalidus DSM 12680 chromosome, complete genomeHAD-superfamily hydrolase, subfamily IA, variant 18e-22103
NC_013156:154233:173726173726174412687Methanocaldococcus fervens AG86, complete genomeHAD superfamily (subfamily IA) hydrolase, TIGR022535e-1787.8
NC_003413:214120:237626237626238285660Pyrococcus furiosus DSM 3638, complete genomehydrolase related to 2-haloalkanoic acid dehalogenase9e-1477
NC_018876:2277160:227827522782752278679405Methanolobus psychrophilus R15 chromosome, complete genomeHAD-superfamily hydrolase, subfamily IA, variant 11e-1376.3
NC_012791:2052923:207046920704692071134666Variovorax paradoxus S110 chromosome 1, complete genomeHAD-superfamily hydrolase, subfamily IA, variant 12e-1272.4
NC_015160:1117371:112113611211361121753618Odoribacter splanchnicus DSM 20712 chromosome, complete genomeHaloacid dehalogenase domain protein hydrolase5e-1271.2
NC_000961:828416:845102845102845842741Pyrococcus horikoshii OT3, complete genomehypothetical protein6e-1271.2
NC_000961:372000:419975419975420673699Pyrococcus horikoshii OT3, complete genomehypothetical protein7e-1270.9
NC_015474:983468:997063997063997761699Pyrococcus sp. NA2 chromosome, complete genomehypothetical protein8e-1270.5
NC_006624:405966:408815408815409468654Thermococcus kodakarensis KOD1, complete genomehydrolase, HAD superfamily1e-1170.1
NC_008942:1198000:121739412173941218080687Methanocorpusculum labreanum Z, complete genomehypothetical protein3e-1168.9
NC_020209:4549563:455327345532734553968696Pseudomonas poae RE*1-1-14, complete genomeHAD-superfamily hydrolase, subfamily IA, variant 1 and 34e-1168.2
NC_004603:230000:245556245556246218663Vibrio parahaemolyticus RIMD 2210633 chromosome I, completehypothetical protein7e-1167.4
NC_000868:1168819:117138311713831172078696Pyrococcus abyssi GE5, complete genomephosphoglycolate phosphatase7e-1064.3
NC_011899:12699:310733107331786714Halothermothrix orenii H 168, complete genomeHAD-superfamily hydrolase, subfamily IA, variant 17e-1064.3
NC_012691:1144715:115767811576781158361684Tolumonas auensis DSM 9187, complete genomeHAD-superfamily hydrolase, subfamily IA, variant 19e-1063.5
NC_014550:3263783:326643532664353267112678Arthrobacter arilaitensis Re117, complete genomehaloacid dehalogenase-like family hydrolase1e-0963.2
NC_009348:2362163:237588923758892376569681Aeromonas salmonicida subsp. salmonicida A449, complete genomeHAD-superfamily hydrolase1e-0963.5
NC_007498:1611986:162945816294581630162705Pelobacter carbinolicus DSM 2380, complete genomehaloacid dehalogenase2e-0962.8
NC_012811:410776:414397414397415077681Methylobacterium extorquens AM1 megaplasmid, complete sequenceputative Hydrolase (HAD superfamily)8e-0960.5
NC_015518:761380:776655776655777260606Acidianus hospitalis W1 chromosome, complete genomeHAD superfamily hydrolase9e-0960.5
NC_014387:719245:735171735171735812642Butyrivibrio proteoclasticus B316 chromosome 1, complete genomeHAD superfamily hydrolase2e-0859.3
NC_011658:4904156:490994549099454910595651Bacillus cereus AH187 chromosome, complete genomepyrophosphatase PpaX2e-0859.3
NC_011969:4841358:484458648445864845236651Bacillus cereus Q1 chromosome, complete genomepyrophosphatase ppax2e-0859.3
NC_016771:4859040:486226848622684862918651Bacillus cereus NC7401, complete genomehaloacid dehalogenase-like family hydrolase2e-0859.3
NC_015977:2807782:283499528349952835618624Roseburia hominis A2-183 chromosome, complete genomehypothetical protein2e-0859.7
NC_017200:4995075:499830349983034998953651Bacillus thuringiensis serovar finitimus YBT-020 chromosome,pyrophosphatase PpaX3e-0858.5
NC_006274:4940922:494310949431094943759651Bacillus cereus E33L, complete genomehydrolase, haloacid dehalogenase-like hydrolase3e-0858.5
NC_012472:4908245:491043249104324911082651Bacillus cereus 03BB102, complete genomehydrolase, haloacid dehalogenase-like family3e-0858.5
NC_005957:4883306:488653448865344887184651Bacillus thuringiensis serovar konkukian str. 97-27, completehydrolase, haloacid dehalogenase-like family3e-0858.5
NC_005945:4877752:488194948819494882599651Bacillus anthracis str. Sterne, complete genomehydrolase, haloacid dehalogenase-like family3e-0858.5
NC_007530:4877500:488073848807384881388651Bacillus anthracis str. 'Ames Ancestor', complete genomehydrolase, haloacid dehalogenase-like family3e-0858.5
NC_003997:4876415:488061248806124881262651Bacillus anthracis str. Ames, complete genomehydrolase, haloacid dehalogenase-like family3e-0858.5
NC_012659:4877410:488063848806384881288651Bacillus anthracis str. A0248, complete genomepyrophosphatase PpaX3e-0858.5
NC_012581:4882525:488306148830614883711651Bacillus anthracis str. CDC 684 chromosome, complete genomepyrophosphatase PpaX3e-0858.9
NC_004722:5057825:506002250600225060672651Bacillus cereus ATCC 14579, complete genomePhosphoglycolate phosphatase3e-0858.9
NC_011772:5021404:502561550256155026265651Bacillus cereus G9842, complete genomehydrolase, haloacid dehalogenase-like family3e-0858.9
NC_014171:4959248:496144549614454962095651Bacillus thuringiensis BMB171 chromosome, complete genomepyrophosphatase PpaX3e-0858.9
NC_017208:5124333:512854451285445129194651Bacillus thuringiensis serovar chinensis CT-43 chromosome, completepyrophosphatase PpaX3e-0858.9
NC_010184:4909183:491498449149844915631648Bacillus weihenstephanensis KBAB4, complete genomeHAD-superfamily hydrolase, subfamily IA, variant 14e-0858.2
NC_011529:1554500:157852715785271579225699Thermococcus onnurineus NA1, complete genomehydrolase5e-0857.8
NC_012779:996879:101180810118081012491684Edwardsiella ictaluri 93-146, complete genomehypothetical protein6e-0857.8
NC_004193:2522000:253591325359132536557645Oceanobacillus iheyensis HTE831, complete genomephosphoglycolate phosphatase7e-0857.4
NC_008322:373531:377357377357378073717Shewanella sp. MR-7, complete genomeHAD-superfamily hydrolase, subfamily IA, variant 18e-0857.4
NC_009033:791515:795497795497796165669Staphylothermus marinus F1, complete genomeHAD-superfamily hydrolase, subfamily IA, variant 31e-0756.6
NC_011725:5075285:507748250774825078132651Bacillus cereus B4264 chromosome, complete genomepyrophosphatase PpaX1e-0756.2
NC_012588:1318879:133214913321491332877729Sulfolobus islandicus M.14.25 chromosome, complete genomeHAD-superfamily hydrolase, subfamily IA, variant13e-0755.5
NC_012632:1399017:141228714122871413015729Sulfolobus islandicus M.16.27 chromosome, complete genomeHAD-superfamily hydrolase3e-0755.5
NC_012726:1292671:132014113201411320869729Sulfolobus islandicus M.16.4 chromosome, complete genomeHAD-superfamily hydrolase, subfamily IA, variant13e-0755.5
NC_017275:1335763:134903313490331349761729Sulfolobus islandicus HVE10/4 chromosome, complete genomeHAD-superfamily hydrolase, subfamily IA, variant13e-0755.5
NC_017276:1206256:121952612195261220254729Sulfolobus islandicus REY15A chromosome, complete genomeHAD-superfamily hydrolase, subfamily IA, variant13e-0755.5
NC_003413:1107965:110972211097221110357636Pyrococcus furiosus DSM 3638, complete genomehypothetical protein3e-0755.5
NC_009997:415808:429122429122429859738Shewanella baltica OS195, complete genomeHAD-superfamily hydrolase, subfamily IA, variant 13e-0755.5
NC_016901:414670:427984427984428721738Shewanella baltica OS678 chromosome, complete genomeHAD superfamily hydrolase3e-0755.5
NC_012589:1395151:140842114084211409149729Sulfolobus islandicus L.S.2.15, complete genomeHAD-superfamily hydrolase, subfamily IA, variant 13e-0755.5
NC_012622:1294479:130774913077491308477729Sulfolobus islandicus Y.G.57.14 chromosome, complete genomeHAD-superfamily hydrolase3e-0755.5
NC_012623:1231332:125558712555871256315729Sulfolobus islandicus Y.N.15.51 chromosome, complete genomeHAD-superfamily hydrolase, subfamily IA, variant13e-0755.5
NC_013769:1403324:141659414165941417322729Sulfolobus islandicus L.D.8.5 chromosome, complete genomeHAD-superfamily hydrolase3e-0755.5
NC_019977:1897556:192680819268081927551744Methanomethylovorans hollandica DSM 15978, complete genomehaloacid dehalogenase superfamily enzyme, subfamily IA4e-0755.1
NC_016641:3217201:323691632369163237677762Paenibacillus terrae HPL-003 chromosome, complete genomeHAD-superfamily hydrolase9e-0753.5
NC_004193:2692136:269393726939372694728792Oceanobacillus iheyensis HTE831, complete genomehypothetical protein2e-0652.8
NC_013891:575746:586613586613587317705Listeria seeligeri serovar 1/2b str. SLCC3954, complete genomeHAD-superfamily hydrolase, subfamily IA, variant 12e-0652.8
NC_002754:595591:619850619850620578729Sulfolobus solfataricus P2, complete genome2-haloalkanoic acid dehalogenase, putative2e-0652.8
NC_017208:3897253:390055639005563901233678Bacillus thuringiensis serovar chinensis CT-43 chromosome, completephosphoglycolate phosphatase3e-0652
NC_011969:3627980:363128336312833631960678Bacillus cereus Q1 chromosome, complete genomehaloacid dehalogenase4e-0651.6
NC_013353:5361207:536318453631845363861678Escherichia coli O103:H2 str. 12009, complete genomehydrolase6e-0650.8
AP010958:5361207:536318453631845363861678Escherichia coli O103:H2 str. 12009 DNA, complete genomepredicted hydrolase6e-0650.8
NC_011750:5045927:505102850510285051705678Escherichia coli IAI39 chromosome, complete genomenucleotidase7e-0650.8