Pre_GI: BLASTP Hits

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Query: NC_010674:3674739:3719058 Clostridium botulinum B str. Eklund 17B, complete genome

Start: 3719058, End: 3719174, Length: 117

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum B str. Eklund 17B is a nonproteolytic botulism neurotoxin B strain. This strain was isolated from marine sediments taken off the coast of Washington, USA and was not associated with botulism. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010674:3674739:368684836868483686964117Clostridium botulinum B str. Eklund 17B, complete genome5S ribosomal RNA5e-1476.6
NC_010674:3674739:369975836997583699874117Clostridium botulinum B str. Eklund 17B, complete genome5S ribosomal RNA5e-1476.6
NC_010674:3674739:368114836811483681264117Clostridium botulinum B str. Eklund 17B, complete genome5S ribosomal RNA5e-1476.6
NC_010674:3674739:371539037153903715506117Clostridium botulinum B str. Eklund 17B, complete genome5S ribosomal RNA5e-1476.6
NC_010723:1:142731427314389117Clostridium botulinum E3 str. Alaska E43, complete genome5S ribosomal RNA2e-1374.3
NC_010723:3530000:357644735764473576563117Clostridium botulinum E3 str. Alaska E43, complete genome5S ribosomal RNA3e-1373.9
NC_010723:3530000:353833235383323538448117Clostridium botulinum E3 str. Alaska E43, complete genome5S ribosomal RNA5e-1373.2
NC_010723:3530000:354422535442253544341117Clostridium botulinum E3 str. Alaska E43, complete genome5S ribosomal RNA5e-1373.2
NC_010723:3530000:356279235627923562908117Clostridium botulinum E3 str. Alaska E43, complete genome5S ribosomal RNA5e-1373.2
NC_010674:3581044:358871435887143588830117Clostridium botulinum B str. Eklund 17B, complete genome5S ribosomal RNA5e-1373.2
NC_010723:3530000:357277435727743572890117Clostridium botulinum E3 str. Alaska E43, complete genome5S ribosomal RNA5e-1373.2
NC_010723:3530000:355094735509473551063117Clostridium botulinum E3 str. Alaska E43, complete genome5S ribosomal RNA5e-1373.2
NC_010674:3674739:369361436936143693730117Clostridium botulinum B str. Eklund 17B, complete genome5S ribosomal RNA5e-1373.2
NC_010674:192951:205433205433205549117Clostridium botulinum B str. Eklund 17B, complete genome5S ribosomal RNA5e-1373.2
NC_010674:3674739:370579737057973705913117Clostridium botulinum B str. Eklund 17B, complete genome5S ribosomal RNA5e-1373.2
NC_010723:3530000:355684035568403556956117Clostridium botulinum E3 str. Alaska E43, complete genome5S ribosomal RNA5e-1373.2
NC_010723:173280:207269207269207385117Clostridium botulinum E3 str. Alaska E43, complete genome5S ribosomal RNA5e-1373.2
NC_010723:3395187:340307934030793403195117Clostridium botulinum E3 str. Alaska E43, complete genome5S ribosomal RNA2e-1270.9
NC_010723:3395187:341994634199463420062117Clostridium botulinum E3 str. Alaska E43, complete genome5S ribosomal RNA2e-1270.9
NC_010674:1:143211432114437117Clostridium botulinum B str. Eklund 17B, complete genome5S ribosomal RNA3e-1270.5
NC_015425:2752482:275884827588482758964117Clostridium botulinum BKT015925 chromosome, complete genome5S ribosomal RNA1e-0652
NC_008593:2457594:246476924647692464885117Clostridium novyi NT, complete genome5S ribosomal RNA3e-0650.4
NC_008593:2527064:253346325334632533579117Clostridium novyi NT, complete genome5S ribosomal RNA3e-0650.4
NC_009699:33452:697436974369859117Clostridium botulinum F str. Langeland chromosome, complete genome5S ribosomal RNA5e-0649.7
NC_009698:467500:479273479273479389117Clostridium botulinum A str. Hall chromosome, complete genome5S ribosomal RNA5e-0649.7
NC_009697:444801:458885458885459001117Clostridium botulinum A str. ATCC 19397 chromosome, complete5S ribosomal RNA5e-0649.7
NC_010516:42475:746917469174807117Clostridium botulinum B1 str. Okra, complete genome5S ribosomal RNA5e-0649.7
NC_012563:36000:689726897269088117Clostridium botulinum A2 str. Kyoto, complete genome5S ribosomal RNA5e-0649.7
NC_010516:42475:676856768567801117Clostridium botulinum B1 str. Okra, complete genome5S ribosomal RNA5e-0649.7
NC_012563:36000:475414754147657117Clostridium botulinum A2 str. Kyoto, complete genome5S ribosomal RNA7e-0649.3
NC_009495:38000:679096790968034126Clostridium botulinum A str. ATCC 3502 chromosome, complete genome5S ribosomal RNA7e-0649.3