Pre_GI: BLASTP Hits

Some Help

Query: NC_010674:222016:229089 Clostridium botulinum B str. Eklund 17B, complete genome

Start: 229089, End: 229514, Length: 426

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum B str. Eklund 17B is a nonproteolytic botulism neurotoxin B strain. This strain was isolated from marine sediments taken off the coast of Washington, USA and was not associated with botulism. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010723:223935:231008231008231433426Clostridium botulinum E3 str. Alaska E43, complete genomeribonuclease III1e-75281
NC_020291:166500:173324173324173737414Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomemini-ribonuclease 31e-50197
NC_009617:163466:171763171763172176414Clostridium beijerinckii NCIMB 8052 chromosome, complete genomeribonuclease III3e-48190
NC_008262:2598920:263984226398422640252411Clostridium perfringens SM101, complete genomeuncharacterized conserved protein, YACZ9e-47185
NC_008593:196257:214312214312214725414Clostridium novyi NT, complete genomehypothetical protein4e-38156
NC_015425:198315:218990218990219403414Clostridium botulinum BKT015925 chromosome, complete genomeRNase3 domain-containing protein4e-37153
NC_010520:3788702:382872338287233829163441Clostridium botulinum A3 str. Loch Maree, complete genomeRNase3 domain protein1e-35148
NC_012563:3956500:399605139960513996491441Clostridium botulinum A2 str. Kyoto, complete genomeRNase3 domain protein2e-35147
NC_010516:3759136:379912237991223799562441Clostridium botulinum B1 str. Okra, complete genomeRNase3 domain protein3e-35146
NC_014393:4482896:452273145227314523144414Clostridium cellulovorans 743B chromosome, complete genomeribonuclease III1e-33141
NC_009633:4563877:459960245996024600030429Alkaliphilus metalliredigens QYMF chromosome, complete genomeribonuclease III7e-31132
NC_014392:1935130:195703619570361957419384Caldicellulosiruptor obsidiansis OB47 chromosome, complete genomeribonuclease III3e-29127
NC_015958:2251619:231418023141802314608429Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genomeribonuclease III4e-28123
NC_017208:108134:110180110180110587408Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein9e-28122
NC_014964:388458:394580394580395008429Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completeribonuclease III7e-27119
NC_010321:393000:399164399164399592429Thermoanaerobacter pseudethanolicus ATCC 33223 chromosome, completeribonuclease III7e-27119
NC_014652:757381:769513769513769947435Caldicellulosiruptor hydrothermalis 108 chromosome, completeribonuclease iii1e-26118
NC_017294:1457262:148856414885641488977414Candidatus Arthromitus sp. SFB-mouse-Yit, complete genomeribonuclease III3e-26117
NC_015913:1491393:152217415221741522587414Candidatus Arthromitus sp. SFB-mouse-Japan, complete genomeribonuclease III3e-26117
NC_010382:4479464:448425644842564484669414Lysinibacillus sphaericus C3-41, complete genomehypothetical protein6e-25112
NC_017338:556319:556319556319556723405Staphylococcus aureus subsp. aureus JKD6159 chromosome, completeribonuclease III1e-24112
NC_007795:511186:515087515087515491405Staphylococcus aureus subsp. aureus NCTC 8325, complete genomehypothetical protein1e-24111
NC_003923:559208:563109563109563513405Staphylococcus aureus subsp. aureus MW2, complete genomehypothetical protein1e-24111
NC_002953:561740:561740561740562144405Staphylococcus aureus subsp. aureus MSSA476, complete genomehypothetical protein1e-24111
NC_002951:596000:599915599915600319405Staphylococcus aureus subsp. aureus COL, complete genomehypothetical protein1e-24111
NC_010079:575123:579024579024579428405Staphylococcus aureus subsp. aureus USA300_TCH1516, completehypothetical protein1e-24111
NC_002758:592892:596793596793597197405Staphylococcus aureus subsp. aureus Mu50, complete genomecysteinyl-tRNA synthetase1e-24111
NC_016928:561138:562531562531562935405Staphylococcus aureus subsp. aureus M013 chromosome, completeribonuclease III family protein2e-24111
NC_007793:574580:578481578481578885405Staphylococcus aureus subsp. aureus USA300, complete genomehypothetical protein1e-24111
NC_009782:596847:598240598240598644405Staphylococcus aureus subsp. aureus Mu3, complete genomecysteinyl-tRNA synthetase1e-24111
NC_017351:566717:570618570618571022405Staphylococcus aureus subsp. aureus 11819-97 chromosome, completehypothetical protein1e-24111
NC_017347:586629:588022588022588426405Staphylococcus aureus subsp. aureus T0131 chromosome, completeRibonuclease III1e-24111
NC_017341:591952:591952591952592356405Staphylococcus aureus subsp. aureus str. JKD6008 chromosome,ribonuclease III1e-24111
NC_016912:511182:515083515083515487405Staphylococcus aureus subsp. aureus VC40 chromosome, completehypothetical protein1e-24111
NC_009641:565103:569004569004569408405Staphylococcus aureus subsp. aureus str. Newman chromosome,hypothetical protein1e-24111
NC_009632:609046:612947612947613351405Staphylococcus aureus subsp. aureus JH1 chromosome, completehypothetical protein1e-24111
NC_009487:609170:613071613071613475405Staphylococcus aureus subsp. aureus JH9 chromosome, completehypothetical protein1e-24111
NC_007622:537195:541097541097541501405Staphylococcus aureus RF122, complete genomehypothetical protein3e-24110
NC_004193:119737:121143121143121559417Oceanobacillus iheyensis HTE831, complete genomehypothetical protein3e-24110
NC_003869:2143892:219520721952072195626420Thermoanaerobacter tengcongensis MB4, complete genomehypothetical protein2e-24110
NC_017337:580850:584784584784585155372Staphylococcus aureus subsp. aureus ED133 chromosome, completeputative cysteinyl-tRNA synthetase4e-24109
NC_002952:582365:583758583758584162405Staphylococcus aureus subsp. aureus MRSA252, complete genomehypothetical protein5e-24109
NC_012470:258287:259623259623260030408Streptococcus equi subsp. zooepidemicus, complete genomemembrane protein1e-23108
NC_016941:549373:551397551397551801405Staphylococcus aureus subsp. aureus MSHR1132, complete genomehypothetical protein2e-23108
NC_014220:2265882:228148522814852281940456Syntrophothermus lipocalidus DSM 12680 chromosome, complete genomeribonuclease III5e-23106
NC_020164:2219612:224530222453022245700399Staphylococcus warneri SG1, complete genomehypothetical protein8e-23105
NC_015555:327562:333491333491333913423Thermoanaerobacterium xylanolyticum LX-11 chromosome, completeribonuclease III1e-22104
NC_004461:277291:294423294423294821399Staphylococcus epidermidis ATCC 12228, complete genomehypothetical protein2e-22104
NC_002976:177282:178675178675179073399Staphylococcus epidermidis RP62A, complete genomehypothetical protein2e-22104
NC_014410:403776:409673409673410086414Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,ribonuclease III1e-21101
NC_019970:336472:363175363175363588414Thermoanaerobacterium thermosaccharolyticum M0795, complete genomehypothetical protein1e-21101
NC_014614:2333890:235025123502512350610360Clostridium sticklandii, complete genomehypothetical protein2e-1994
NC_010320:881351:885191885191885523333Thermoanaerobacter sp. X514 chromosome, complete genomehypothetical protein1e-1892
NC_011884:1821862:182186218218621822323462Cyanothece sp. PCC 7425, complete genomeribonuclease III3e-1890.5
NC_010718:193231:196737196737197162426Natranaerobius thermophilus JW/NM-WN-LF, complete genomeribonuclease III6e-1682.8
NC_008820:1356858:138264013826401383047408Prochlorococcus marinus str. MIT 9303, complete genomehypothetical protein8e-1475.9
NC_005071:704882:706504706504706911408Prochlorococcus marinus str. MIT 9313, complete genomehypothetical protein8e-1475.9
NC_009828:1530732:154668415466841547061378Thermotoga lettingae TMO, complete genomehypothetical protein1e-0962
NC_003454:63500:884978849788886390Fusobacterium nucleatum subsp. nucleatum ATCC 25586, completehypothetical protein8e-0959.3