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Query: NC_010673:908940:3680 Borrelia hermsii DAH, complete genome

Start: 3680, End: 5467, Length: 1788

Host Lineage: Borrelia hermsii; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: This strain was isolated from a case of relapsing fever in western Washington, USA. Borrelia hermsii is the causative agent of tick-borne relapsing fever in the western United States and Canada. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the organism into a mammalian host through its infectious saliva. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another. These plasmids carry genes involved in antigenic variation and pathogenicity.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008710:900586:3262326251451884Borrelia turicatae 91E135, complete genomephosphomannomutase0976
NC_011244:1:1621816218180081791Borrelia recurrentis A1, complete genomephosphoglucomutase0893
NC_015577:2203835:2220429222042922222251797Treponema azotonutricium ZAS-9 chromosome, complete genomephosphohexose mutase family protein4e-96352
NC_010003:2029416:2046323204632320480021680Petrotoga mobilis SJ95, complete genomephosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I3e-0653.9
NC_007681:1455425:1463928146392814652861359Methanosphaera stadtmanae DSM 3091, complete genomepredicted phosphomannomutase6e-0653.1