Pre_GI: BLASTP Hits

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Query: NC_010673:908940:2079 Borrelia hermsii DAH, complete genome

Start: 2079, End: 3533, Length: 1455

Host Lineage: Borrelia hermsii; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: This strain was isolated from a case of relapsing fever in western Washington, USA. Borrelia hermsii is the causative agent of tick-borne relapsing fever in the western United States and Canada. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the organism into a mammalian host through its infectious saliva. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another. These plasmids carry genes involved in antigenic variation and pathogenicity.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008710:900586:1743174331971455Borrelia turicatae 91E135, complete genomeUTP--glucose-1-phosphate uridylyltransferase0780
NC_011244:1:1467014670161631494Borrelia recurrentis A1, complete genomehypothetical protein0725
NC_013521:2193203:2205669220566922070661398Sanguibacter keddieii DSM 10542, complete genomeUDP-glucose pyrophosphorylase5e-0756.2