Pre_GI: BLASTP Hits

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Query: NC_010660:175200:179672 Shigella boydii CDC 3083-94 plasmid pBS512_211, complete sequence

Start: 179672, End: 179947, Length: 276

Host Lineage: Shigella boydii; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain (strain BS512; serotype 18) was originally isolated from a 12-year-old boy in Arizona, USA by Dr. Nancy Stockbine. It is a member of Group 1 as determined by limited sequence analysis and can invade HeLa cells. Pathogenicity and virulence have been verified during in vitro experimentation, and multiple plasmids are present in this strain. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. Shigella spp. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This species is uncommon except in India, where it was first isolated. Progression to clinical dysentery occurs in most patients infected with this organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_004851:157675:178876178876179178303Shigella flexneri 2a str. 301 plasmid pCP301, complete sequenceputative IS1 encoded protein1e-30131
NC_004337:2035945:2050214205021420512481035Shigella flexneri 2a str. 301, complete genomeIS600 ORF22e-29127
NC_008258:2190635:219995521999552200188234Shigella flexneri 5 str. 8401, complete genomeputative IS1 encoded protein4e-29126
NC_008258:269806:284251284251284493243Shigella flexneri 5 str. 8401, complete genomeputative IS1 encoded protein5e-29126
NC_010658:2529033:252961125296112530024414Shigella boydii CDC 3083-94, complete genometransposase1e-28125
NC_008258:1750964:175751217575121757739228Shigella flexneri 5 str. 8401, complete genomeputative IS1 encoded protein1e-28125
NC_004337:3590323:369261536926153693283669Shigella flexneri 2a str. 301, complete genomeIS150 ORF1(ORF A)2e-28124
NC_008258:3995553:399956839995683999786219Shigella flexneri 5 str. 8401, complete genomeputative IS1 encoded protein2e-28124
NC_008258:3550500:357198435719843572226243Shigella flexneri 5 str. 8401, complete genomeputative IS1 encoded protein2e-28124
NC_010658:3014371:301893630189363019244309Shigella boydii CDC 3083-94, complete genomeputative IS1 encoded protein2e-28124
NC_010658:4494103:450182545018254502505681Shigella boydii CDC 3083-94, complete genomehypothetical protein1e-28124
NC_010658:3622610:362924336292433629449207Shigella boydii CDC 3083-94, complete genomeputative IS1 encoded protein4e-28123
NC_008258:4345400:436211743621174362419303Shigella flexneri 5 str. 8401, complete genomeputative IS1 encoded protein4e-28123
NC_010658:1193225:120564212056421205896255Shigella boydii CDC 3083-94, complete genomeputative IS1 encoded protein4e-28123
NC_010658:1193225:121427612142761214500225Shigella boydii CDC 3083-94, complete genomeputative IS1 encoded protein3e-28123
NC_008258:1784637:179439417943941794627234Shigella flexneri 5 str. 8401, complete genomeputative IS1 encoded protein3e-28123
NC_017328:1835108:184761318476131847846234Shigella flexneri 2002017 chromosome, complete genomeputative IS1 encoded protein3e-28123
NC_008258:3581583:358741335874133587664252Shigella flexneri 5 str. 8401, complete genomeputative IS1 encoded protein3e-28123
NC_004337:3590323:381860038186003819571972Shigella flexneri 2a str. 301, complete genomehypothetical protein3e-28123
NC_008258:1750964:176193117619311762167237Shigella flexneri 5 str. 8401, complete genomeputative IS1 encoded protein1e-27122
NC_007613:2699500:270599027059902706172183Shigella boydii Sb227, complete genomeputative IS1 encoded protein8e-28122
NC_008258:2045000:204571820457182045993276Shigella flexneri 5 str. 8401, complete genomeputative IS1 encoded protein6e-28122
NC_017328:2090679:209265220926522092927276Shigella flexneri 2002017 chromosome, complete genomeputative IS1 encoded protein6e-28122
NC_004337:3590323:361094436109443611270327Shigella flexneri 2a str. 301, complete genomeputative IS1 encoded protein5e-28122
NC_017328:3655876:366205036620503662259210Shigella flexneri 2002017 chromosome, complete genomeIS150 ORF15e-28122
NC_007613:4217557:424498542449854245218234Shigella boydii Sb227, complete genomeputative IS1 encoded protein1e-27121
NC_017328:385552:3942543942543966772424Shigella flexneri 2002017 chromosome, complete genomehypothetical protein1e-27121
NC_007613:3470314:347560334756033475815213Shigella boydii Sb227, complete genomeputative IS1 encoded protein1e-27121
NC_008258:4345400:436031743603174360583267Shigella flexneri 5 str. 8401, complete genomeputative IS1 encoded protein1e-27121
NC_007613:4156841:417569641756964175926231Shigella boydii Sb227, complete genomeputative IS1 encoded protein1e-27121
NC_010658:3014371:302971830297183029966249Shigella boydii CDC 3083-94, complete genometransposase1e-27121
NC_008258:1784637:179112117911211791309189Shigella flexneri 5 str. 8401, complete genomeputative IS1 encoded protein3e-27120
NC_008258:1750964:175453017545301754709180Shigella flexneri 5 str. 8401, complete genomeputative IS1 encoded protein3e-27120
NC_008258:3224721:324186332418633242042180Shigella flexneri 5 str. 8401, complete genomeputative IS1 encoded protein3e-27120
NC_004337:3590323:360836036083603608683324Shigella flexneri 2a str. 301, complete genomeputative IS1 encoded protein2e-27120
NC_004337:4374500:439250143925014392824324Shigella flexneri 2a str. 301, complete genomeputative IS1 encoded protein2e-27120
NC_017328:4417000:443621344362134436536324Shigella flexneri 2002017 chromosome, complete genomeIS600 ORF22e-27120
NC_010658:4257310:427454442745444274732189Shigella boydii CDC 3083-94, complete genomeputative IS1 encoded protein2e-27120
NC_010658:4494103:449905944990594499292234Shigella boydii CDC 3083-94, complete genometransposase4e-27119
NC_008258:2905413:291300729130072913213207Shigella flexneri 5 str. 8401, complete genomeputative IS1 encoded protein5e-27119
NC_010658:4257310:426604242660424266227186Shigella boydii CDC 3083-94, complete genometransposase1e-26118
NC_007613:2981829:298999829899982990288291Shigella boydii Sb227, complete genomeputative IS1 encoded protein2e-24110
NC_007613:1038000:104694910469491047122174Shigella boydii Sb227, complete genomeputative IS1 encoded protein3e-24110
NC_007613:4403070:440815544081554408331177Shigella boydii Sb227, complete genomeputative IS1-encoded protein5e-24109
NC_007613:1038000:105726810572681057438171Shigella boydii Sb227, complete genomeputative IS1 encoded protein5e-24109
NC_007613:4119771:413590741359074136077171Shigella boydii Sb227, complete genomeputative IS1 encoded protein4e-24109
NC_007613:761234:763110763110763292183Shigella boydii Sb227, complete genomeputative IS1 encoded protein1e-23108
NC_007613:1038000:104126210412621041429168Shigella boydii Sb227, complete genomeputative IS1 encoded protein2e-23107
NC_007613:3470314:347899834789983479168171Shigella boydii Sb227, complete genomeputative IS1 encoded protein3e-23107
NC_007613:4119771:412460941246094124776168Shigella boydii Sb227, complete genomeputative IS1 encoded protein3e-23107
NC_007613:4217557:423946642394664239642177Shigella boydii Sb227, complete genomeputative IS1 encoded protein1e-22104
NC_007613:4217557:424181142418114242452642Shigella boydii Sb227, complete genomehypothetical protein2e-2097.8
NC_017328:3088907:314376031437603144023264Shigella flexneri 2002017 chromosome, complete genomeputative IS1 encoded protein3e-2097.1
NC_017328:4417000:442183744218374422040204Shigella flexneri 2002017 chromosome, complete genomeputative integrase encoded by prophage CP-933K5e-2096.3
NC_008258:3581583:359822535982253598854630Shigella flexneri 5 str. 8401, complete genomeIS150 ORF1(ORF A)5e-2096.3
NC_017328:3794105:381084038108403811019180Shigella flexneri 2002017 chromosome, complete genomeputative integrase encoded by prophage CP-933K7e-2095.9
NC_017328:3655876:367282036728203672960141Shigella flexneri 2002017 chromosome, complete genomeIS600 ORF21e-1994.7
NC_010468:1775000:1792029179202917936171589Escherichia coli ATCC 8739, complete genome3e-1993.6
NC_017328:4417000:443213344321334432360228Shigella flexneri 2002017 chromosome, complete genomeIS600 ORF23e-1993.6
NC_017328:3794105:379472237947223794865144Shigella flexneri 2002017 chromosome, complete genomeputative integrase encoded by prophage CP-933K6e-1992.8
NC_007384:3956465:3974605397460539764161812Shigella sonnei Ss046, complete genome6e-1992.8
NC_017328:3625000:364631336463133646516204Shigella flexneri 2002017 chromosome, complete genomeIS150 ORF15e-1992.8
NC_017328:2225418:223949922394992239660162Shigella flexneri 2002017 chromosome, complete genomeIS600 ORF28e-1992.4
NC_017328:3655876:365972336597233660127405Shigella flexneri 2002017 chromosome, complete genomeputative alpha-mannosidase3e-1890.5
NC_007384:1086025:1107697110769711088591163Shigella sonnei Ss046, complete genome7e-1889.4
NC_020260:882307:911776911776911997222Cronobacter sakazakii Sp291, complete genomehypothetical protein1e-1582
NC_010660:175200:191466191466191591126Shigella boydii CDC 3083-94 plasmid pBS512_211, complete sequence5e-0753.1
NC_010658:1772994:177621317762131776326114Shigella boydii CDC 3083-94, complete genome6e-0753.1
NC_010658:4257310:426468142646814264794114Shigella boydii CDC 3083-94, complete genome6e-0752.8