Pre_GI: BLASTP Hits

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Query: NC_010520:3204480:3205219 Clostridium botulinum A3 str. Loch Maree, complete genome

Start: 3205219, End: 3205719, Length: 501

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A3 str. Loch Maree was isolated from duck liver paste during a botulism outbreak at a hotel in the Scottish highlands in 1922. This was the first and worst outbreak of botulism in the United Kingdom (UK). This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012563:3374904:337564333756433376143501Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein TIGR000431e-87322
NC_012658:3213498:321423732142373214737501Clostridium botulinum Ba4 str. 657 chromosome, complete genomeputative metalloprotease3e-87320
NC_009495:3138355:313909231390923139592501Clostridium botulinum A str. ATCC 3502 chromosome, complete genomemetalloprotease3e-87320
NC_009697:3071198:307193530719353072435501Clostridium botulinum A str. ATCC 19397 chromosome, completemetalloprotease3e-87320
NC_009698:3006500:300885730088573009357501Clostridium botulinum A str. Hall chromosome, complete genomemetalloprotease3e-87320
NC_010516:3196158:319689731968973197397501Clostridium botulinum B1 str. Okra, complete genomeconserved hypothetical protein TIGR000432e-87320
NC_009699:3178222:317944331794433179943501Clostridium botulinum F str. Langeland chromosome, complete genomemetalloprotease2e-87320
NC_017297:3178378:317959931795993180099501Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein2e-87320
NC_020291:1014333:103282010328201033320501Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomemetalloprotein, YbeY/UPF0054 family3e-56216
NC_011898:649000:669196669196669681486Clostridium cellulolyticum H10, complete genomeprotein of unknown function UPF00543e-36150
NC_013171:342714:3737193737193750591341Anaerococcus prevotii DSM 20548, complete genomeprotein of unknown function UPF00546e-31133
NC_009633:3055413:306265430626543063121468Alkaliphilus metalliredigens QYMF chromosome, complete genomehypothetical protein1e-28125
NC_009674:3073564:307522630752263075696471Bacillus cytotoxicus NVH 391-98 chromosome, complete genomeputative metalloprotease2e-28125
NC_005957:4104880:410441341044134104883471Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein1e-25115
NC_007530:4117071:411660441166044117074471Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein1e-25115
NC_014335:4027105:402663840266384027108471Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein1e-25115
NC_008600:4101748:410349441034944103964471Bacillus thuringiensis str. Al Hakam, complete genomehypothetical protein1e-25115
NC_003997:4116944:411647741164774116947471Bacillus anthracis str. Ames, complete genomehypothetical protein1e-25115
NC_012472:4119192:412093841209384121408471Bacillus cereus 03BB102, complete genomeconserved hypothetical protein TIGR000431e-25115
NC_003909:4064904:406490440649044065374471Bacillus cereus ATCC 10987, complete genomehypothetical protein1e-25115
NC_005945:4116978:411697841169784117448471Bacillus anthracis str. Sterne, complete genomehypothetical protein1e-25115
NC_006274:4159096:415862941586294159099471Bacillus cereus E33L, complete genomehypothetical protein1e-25115
NC_011658:4107501:410924741092474109717471Bacillus cereus AH187 chromosome, complete genomeputative metalloprotease1e-25115
NC_011773:4108855:410838841083884108858471Bacillus cereus AH820 chromosome, complete genomeputative metalloprotease1e-25115
NC_011969:4001489:400433540043354004805471Bacillus cereus Q1 chromosome, complete genomemetalloprotease1e-25115
NC_012581:4118366:411789941178994118369471Bacillus anthracis str. CDC 684 chromosome, complete genomeputative metalloprotease1e-25115
NC_012659:4116971:411650441165044116974471Bacillus anthracis str. A0248, complete genomeputative metalloprotease1e-25115
NC_016771:4059445:406303140630314063501471Bacillus cereus NC7401, complete genomehypothetical protein1e-25115
NC_016779:4039103:403863640386364039106471Bacillus cereus F837/76 chromosome, complete genomeMetal-dependent hydrolase1e-25115
NC_002570:1426000:144959014495901450069480Bacillus halodurans C-125, complete genomehypothetical protein1e-24112
NC_007622:1558753:155951515595151559982468Staphylococcus aureus RF122, complete genomehypothetical protein8e-25112
NC_010184:4155345:415487841548784155348471Bacillus weihenstephanensis KBAB4, complete genomeprotein of unknown function UPF00543e-23107
NC_018515:4148037:414803741480374148510474Desulfosporosinus meridiei DSM 13257 chromosome, complete genomemetalloprotein1e-22105
NC_013895:1086500:1104674110467411063651692Clostridiales genomosp. BVAB3 str. UPII9-5 chromosome, completeGTP-binding protein Era3e-21101
NC_017192:1137724:113907011390701139489420Arcobacter sp. L, complete genomeputative metalloprotease4e-21100
NC_011999:1320159:132400313240031324467465Macrococcus caseolyticus JCSC5402, complete genomehypothetical protein4e-2097.4
NC_012438:818387:823460823460823912453Sulfurihydrogenibium azorense Az-Fu1 chromosome, complete genomehypothetical protein2e-1788.2
NC_014935:1511835:152729415272941527722429Nitratifractor saLSUginis DSM 16511 chromosome, complete genomehypothetical protein3e-1787.8
NC_012004:470492:472284472284472784501Streptococcus uberis 0140J, complete genomehypothetical protein5e-1787
NC_013198:1538792:156878115687811569239459Lactobacillus rhamnosus GG, complete genomemetal-dependent hydrolase6e-1786.7
NC_013517:2055071:207431420743142074772459Sebaldella termitidis ATCC 33386, complete genomeprotein of unknown function UPF00542e-1685.1
NC_012470:580373:583391583391583936546Streptococcus equi subsp. zooepidemicus, complete genomehypothetical protein3e-1684.3
NC_013947:4917711:493163549316354932105471Stackebrandtia nassauensis DSM 44728 chromosome, complete genomehypothetical protein1e-1582.4
NC_010612:4501414:452445645244564524992537Mycobacterium marinum M, complete genomeconserved hypothetical metal-dependent hydrolase5e-1580.1
NC_002944:2373873:239194423919442392477534Mycobacterium avium subsp. paratuberculosis K-10, complete genomehypothetical protein1e-1479
NC_015387:1091403:110921611092161109641426Marinithermus hydrothermalis DSM 14884 chromosome, complete genomemetalloprotease ybeY6e-1476.6
NC_009714:671897:688306688306688722417Campylobacter hominis ATCC BAA-381, complete genomeputative metalloprotease9e-1476.3
NC_011297:1167615:116761511676151168043429Dictyoglomus thermophilum H-6-12, complete genomehypothetical protein5e-1373.6
NC_011661:1332309:134804013480401348468429Dictyoglomus turgidum DSM 6724, complete genomeprotein of unknown function UPF00549e-1372.8
NC_007759:1571425:159104215910421591524483Syntrophus aciditrophicus SB, complete genomepredicted metal-dependent hydrolase2e-1168.2
NC_000853:1480478:150592715059271506379453Thermotoga maritima MSB8, complete genomehypothetical protein4e-1167.4
NC_011978:975333:974903974903975352450Thermotoga neapolitana DSM 4359, complete genomePutative metalloprotease5e-1167
NC_012115:691154:716351716351716770420Nautilia profundicola AmH, complete genomehypothetical protein5e-1167
NC_015276:3321277:332232633223263322793468Marinomonas mediterranea MMB-1 chromosome, complete genomemetalloprotease ybeY9e-1166.2
NC_010483:1385000:141303614130361413488453Thermotoga sp. RQ2, complete genomeprotein of unknown function UPF00541e-1065.5
NC_008340:420126:442315442315442815501Alkalilimnicola ehrlichei MLHE-1, complete genomeprotein of unknown function UPF00546e-1063.5
NC_013642:1317114:131828913182891318741453Thermotoga naphthophila RKU-10, complete genomeprotein of unknown function UPF00545e-1063.5
NC_009486:1293510:129468512946851295137453Thermotoga petrophila RKU-1 chromosome, complete genomehypothetical protein5e-1063.5
NC_012913:167034:184700184700185164465Aggregatibacter aphrophilus NJ8700, complete genomeputative metalloprotease in flp 5' region8e-1063.2
NC_007298:3764048:378075637807563781205450Dechloromonas aromatica RCB, complete genomehypothetical protein2e-0961.2
NC_016638:816643:854936854936855334399Mycoplasma haemocanis str. Illinois chromosome, complete genomehypothetical protein2e-0961.2
NC_016513:974402:994401994401994865465Aggregatibacter actinomycetemcomitans ANH9381 chromosome, completeputative metalloprotease in flp 5' region3e-0961.2
NC_015222:386000:386034386034386540507Nitrosomonas sp. AL212 chromosome, complete genomehypothetical protein3e-0857.8
NC_013416:668152:687981687981688445465Aggregatibacter actinomycetemcomitans D11S-1, complete genomeputative metalloprotease in flp 5' region3e-0857.8
NC_015856:4203301:422172642217264222193468Collimonas fungivorans Ter331 chromosome, complete genomeputative metal-dependent hydrolase5e-0857
NC_016616:1233555:124851112485111248969459Dechlorosoma suillum PS chromosome, complete genomeYbeY family metalloprotein9e-0856.2
NC_016612:3087615:310337731033773103844468Klebsiella oxytoca KCTC 1686 chromosome, complete genomemetal-binding heat shock protein1e-0755.8
NC_013061:1:773377338161429Pedobacter heparinus DSM 2366, complete genomeprotein of unknown function UPF00541e-0755.5
NC_018721:2017737:202618420261842026615432Psychroflexus torquis ATCC 700755 chromosome, complete genomemetal-dependent hydrolase, putative9e-0752.8
NC_010524:4402478:442850744285074428989483Leptothrix cholodnii SP-6, complete genomeprotein of unknown function UPF00541e-0652.4
NC_010278:1045884:106531610653161065807492Actinobacillus pleuropneumoniae serovar 3 str. JL03 chromosome,putative metalloprotease1e-0652
NC_013037:4623179:462855746285574628997441Dyadobacter fermentans DSM 18053, complete genomeprotein of unknown function UPF00542e-0652
NC_013523:959625:976611976611977072462Sphaerobacter thermophilus DSM 20745 chromosome 1, complete genomeprotein of unknown function UPF00544e-0650.8
NC_006347:143876:166147166147166566420Bacteroides fragilis YCH46, complete genomehypothetical protein6e-0650.1
NC_016609:7819243:782809878280987828547450Niastella koreensis GR20-10 chromosome, complete genomemetalloprotease ybeY7e-0650.1