Pre_GI: BLASTP Hits

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Query: NC_010520:3120500:3132188 Clostridium botulinum A3 str. Loch Maree, complete genome

Start: 3132188, End: 3132892, Length: 705

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A3 str. Loch Maree was isolated from duck liver paste during a botulism outbreak at a hotel in the Scottish highlands in 1922. This was the first and worst outbreak of botulism in the United Kingdom (UK). This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012658:3126108:313652431365243137228705Clostridium botulinum Ba4 str. 657 chromosome, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase3e-118424
NC_009698:2921097:293166129316612932365705Clostridium botulinum A str. Hall chromosome, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase1e-116418
NC_009697:2984173:299473729947372995441705Clostridium botulinum A str. ATCC 19397 chromosome, completephosphoribosylaminoimidazole-succinocarboxamide synthase1e-116418
NC_009495:3051223:306178730617873062491705Clostridium botulinum A str. ATCC 3502 chromosome, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase1e-116418
NC_012563:3288124:329881632988163299520705Clostridium botulinum A2 str. Kyoto, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase1e-116418
NC_003030:1510000:153478015347801535487708Clostridium acetobutylicum ATCC 824, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase3e-94344
NC_009617:1255762:126515612651561265863708Clostridium beijerinckii NCIMB 8052 chromosome, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase2e-93342
NC_014328:938393:942856942856943563708Clostridium ljungdahlii ATCC 49587 chromosome, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase9e-93339
NC_021182:2059143:206740820674082068118711Clostridium pasteurianum BC1, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase8e-92336
NC_020291:1266885:127403712740371274744708Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase PurC2e-90331
NC_008593:1631438:164380116438011644508708Clostridium novyi NT, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase1e-89329
NC_010723:1084000:109376910937691094476708Clostridium botulinum E3 str. Alaska E43, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase6e-89327
NC_010674:1124431:113187111318711132578708Clostridium botulinum B str. Eklund 17B, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase2e-88325
NC_008262:784878:792737792737793444708Clostridium perfringens SM101, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase8e-88323
NC_003366:842000:849929849929850636708Clostridium perfringens str. 13, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase5e-87320
NC_015732:2710913:271356827135682714278711Spirochaeta caldaria DSM 7334 chromosome, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase3e-86318
NC_015425:1867620:188303318830331883740708Clostridium botulinum BKT015925 chromosome, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase1e-85315
NC_014633:265086:278102278102278812711Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequencephosphoribosylaminoimidazole-succinocarboxamide synthase4e-83307
NC_015958:677500:693819693819694526708Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase3e-74278
NC_009633:947695:953881953881954591711Alkaliphilus metalliredigens QYMF chromosome, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase3e-74278
NC_009253:2577316:259365625936562594366711Desulfotomaculum reducens MI-1 chromosome, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase1e-67255
NC_017179:281069:285836285836286534699Clostridium difficile BI1, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase3e-67254
NC_015161:199666:203362203362204075714Deinococcus proteolyticus MRP chromosome, complete genomePhosphoribosylaminoimidazole-succinocarboxamide synthase2e-66251
NC_016023:1725294:174059817405981741308711Bacillus coagulans 36D1 chromosome, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase8e-65246
NC_011567:238249:255046255046255768723Anoxybacillus flavithermus WK1, complete genomePhosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase1e-63243
NC_014614:356746:380849380849381544696Clostridium sticklandii, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthetase4e-63241
NC_010556:462500:477424477424478131708Exiguobacterium sibiricum 255-15, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase3e-62238
NC_009484:429269:450323450323451087765Acidiphilium cryptum JF-5 chromosome, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase1e-61236
NC_014171:261952:320708320708321427720Bacillus thuringiensis BMB171 chromosome, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase9e-61233
NC_018665:422451:437183437183437890708Exiguobacterium antarcticum B7 chromosome, complete genomePhosphoribosylaminoimidazole-succinocarboxamide synthase2e-60232
NC_010172:632180:648314648314649108795Methylobacterium extorquens PA1, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase5e-60231
NC_011757:577611:593751593751594545795Methylobacterium chloromethanicum CM4, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase5e-60231
NC_010725:594500:610132610132610926795Methylobacterium populi BJ001, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase3e-60231
NC_017208:256163:310366310366311085720Bacillus thuringiensis serovar chinensis CT-43 chromosome, completephosphoribosylaminoimidazolesuccinocarboxamide synthase3e-60231
NC_012808:420334:436145436145436909765Methylobacterium extorquens AM1, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthetase (SAICAR synthetase)6e-60230
NC_010505:3690000:370468637046863705480795Methylobacterium radiotolerans JCM 2831, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase8e-60229
NC_008022:35983:359833598336717735Streptococcus pyogenes MGAS10270, complete genomePhosphoribosylaminoimidazole-succinocarboxamide synthase4e-57221
NC_003485:35971:359713597136705735Streptococcus pyogenes MGAS8232, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase4e-57221
NC_014664:493900:513800513800514576777Rhodomicrobium vannielii ATCC 17100 chromosome, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase4e-57221
NC_018704:433402:438580438580439290711Amphibacillus xylanus NBRC 15112, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase3e-57221
NC_008024:35948:359483594836682735Streptococcus pyogenes MGAS10750, complete genomePhosphoribosylamidoimidazole-succinocarboxamide synthase3e-57221
NC_007799:257500:272596272596273324729Ehrlichia chaffeensis str. Arkansas, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase2e-57221
NC_007296:35661:356613566136395735Streptococcus pyogenes MGAS6180, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase6e-57220
NC_008021:35661:356613566136395735Streptococcus pyogenes MGAS9429, complete genomephosphoribosylamidoimidazole-succinocarboxamide synthase6e-57220
NC_008023:35663:356633566336397735Streptococcus pyogenes MGAS2096, complete genomePhosphoribosylaminoimidazole-succinocarboxamide synthase6e-57220
NC_006086:35599:768277682777561735Streptococcus pyogenes MGAS10394, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase8e-57220
NC_015391:2488450:250518725051872505933747Carnobacterium sp. 17-4 chromosome, complete genomephosphoribosylaminoimidazole- succinocarboxamidesynthase2e-56219
NC_004193:783958:789966789966790679714Oceanobacillus iheyensis HTE831, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase1e-56219
NC_007797:107950:127341127341128075735Anaplasma phagocytophilum HZ, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase8e-55213
NC_007354:997580:100256010025601003336777Ehrlichia canis str. Jake, complete genomeSAICAR synthetase9e-55213
NC_015499:119200:133283133283133978696Thermodesulfobium narugense DSM 14796 chromosome, complete genomePhosphoribosylaminoimidazole-succinocarboxamide synthase2e-54212
NC_010501:4379920:439418143941814394891711Pseudomonas putida W619, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase5e-54211
NC_012925:29353:307193071931426708Streptococcus suis P1/7, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase8e-54210
NC_009443:29349:307153071531422708Streptococcus suis 98HAH33, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase8e-54210
NC_012924:29353:307193071931426708Streptococcus suis SC84, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase8e-54210
NC_012926:30351:307173071731424708Streptococcus suis BM407 chromosome, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase8e-54210
NC_007168:1923723:193754319375431938247705Staphylococcus haemolyticus JCSC1435, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase8e-54210
NC_017986:4091051:409517040951704095880711Pseudomonas putida ND6 chromosome, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase6e-54210
NC_004461:746284:753286753286753990705Staphylococcus epidermidis ATCC 12228, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase4e-53207
NC_002976:638799:645802645802646506705Staphylococcus epidermidis RP62A, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase4e-53207
NC_014829:443500:450336450336451049714Bacillus cellulosilyticus DSM 2522 chromosome, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase3e-53207
NC_020164:1784223:179606917960691796773705Staphylococcus warneri SG1, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase1e-52206
NC_018080:4436646:445180144518014452511711Pseudomonas aeruginosa DK2 chromosome, complete genomephosphoribosylaminoimidazole succinocarboxamide synthase1e-52206
NC_014935:1511835:151606915160691516788720Nitratifractor saLSUginis DSM 16511 chromosome, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase2e-52206
NC_007005:1738500:174414717441471744857711Pseudomonas syringae pv. syringae B728a, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase1e-51202
NC_013928:9494:317583175832465708Streptococcus mutans NN2025, complete genomephosphoribosylaminoimidazole- succinocarboxamide synthase5e-51201
NC_011999:728353:741524741524742225702Macrococcus caseolyticus JCSC5402, complete genomephosphoribosylaminoimidazole succinocarboxamide synthetase3e-50198
NC_013665:2495234:251940925194092520125717Methanocella paludicola SANAE, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase2e-48192
NC_016830:1645879:165116916511691651882714Pseudomonas fluorescens F113 chromosome, complete genomeprotein PurC3e-46185
NC_003106:1484768:148778214877821488486705Sulfolobus tokodaii str. 7, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase4e-39161
NC_015518:997707:101808410180841018791708Acidianus hospitalis W1 chromosome, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase1e-38159
NC_009440:1908864:191147619114761912177702Metallosphaera sedula DSM 5348 chromosome, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase8e-37153
NC_002754:537792:542822542822543523702Sulfolobus solfataricus P2, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase8e-36150
NC_012589:1482075:149768114976811498382702Sulfolobus islandicus L.S.2.15, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase2e-35149
NC_012588:1394103:140970914097091410410702Sulfolobus islandicus M.14.25 chromosome, complete genomephosphoribosylaminoimidazole succinocarboxamide synthase2e-35149
NC_012622:1371448:138705413870541387755702Sulfolobus islandicus Y.G.57.14 chromosome, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase2e-35149
NC_012623:1167289:117033711703371171038702Sulfolobus islandicus Y.N.15.51 chromosome, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase2e-35149
NC_012632:1518520:153412615341261534827702Sulfolobus islandicus M.16.27 chromosome, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase2e-35149
NC_012726:1382095:139770113977011398402702Sulfolobus islandicus M.16.4 chromosome, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase2e-35149
NC_013769:1478546:149415214941521494853702Sulfolobus islandicus L.D.8.5 chromosome, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase2e-35149
NC_017275:1436875:145248214524821453183702Sulfolobus islandicus HVE10/4 chromosome, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase2e-35149
NC_017276:1285824:130143113014311302132702Sulfolobus islandicus REY15A chromosome, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase2e-35149
NC_015435:251958:274431274431275135705Metallosphaera cuprina Ar-4 chromosome, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase2e-35149
NC_014471:217279:221636221636222367732Ignisphaera aggregans DSM 17230 chromosome, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase5e-34144
NC_009718:1183816:119337311933731194068696Fervidobacterium nodosum Rt17-B1, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase9e-34143
NC_016930:293245:299091299091299801711Rickettsia philipii str. 364D chromosome, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase2e-32139
NC_016913:859931:866510866510867220711Rickettsia rickettsii str. Brazil chromosome, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase2e-32139
NC_016915:278000:301521301521302231711Rickettsia rickettsii str. Hlp#2 chromosome, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase2e-32139
NC_017043:990395:101894410189441019654711Rickettsia montanensis str. OSU 85-930 chromosome, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase2e-32139
NC_006142:262825:270336270336271046711Rickettsia typhi str. Wilmington, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase1e-32139
NC_017066:262839:270350270350271060711Rickettsia typhi str. TH1527 chromosome, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase1e-32139
NC_007181:1364522:136828513682851368992708Sulfolobus acidocaldarius DSM 639, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase3e-31135
NC_010793:81219:920169201692750735Orientia tsutsugamushi str. Ikeda, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase2e-29129
NC_014537:542515:558823558823559542720Vulcanisaeta distributa DSM 14429 chromosome, complete genomephosphoribosylaminoimidazole-succinocarboxamides ynthase1e-29129
NC_015151:1872280:190505819050581905777720Vulcanisaeta moutnovskia 768-28 chromosome, complete genomephosphoribosylaminoimidazolesuccinocarboxamidesy nthase9e-29127
NC_011653:1463743:148738914873891488075687Thermosipho africanus TCF52B, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase4e-24111
NC_010644:231486:236226236226236906681Elusimicrobium minutum Pei191, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase2e-1375.9
NC_007759:1169547:117600911760091176725717Syntrophus aciditrophicus SB, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase1e-1067
NC_016627:4535000:454225845422584543142885Clostridium clariflavum DSM 19732 chromosome, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase9e-0960.5
NC_011985:194973:194973194973195962990Agrobacterium radiobacter K84 chromosome 1, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase2e-0756.6
NC_008711:3701635:372163037216303722568939Arthrobacter aurescens TC1, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase1e-0756.6
NC_015690:8019859:802318680231868024079894Paenibacillus mucilaginosus KNP414 chromosome, complete genomephosphoribosylaminoimidazolesuccinocarboxamide synthase2e-0756.2
NC_011898:426951:438189438189439085897Clostridium cellulolyticum H10, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase2e-0756.2
NC_014210:5270643:528106752810675281903837Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,phosphoribosylaminoimidazole-succinocarboxamide synthase4e-0755.1
NC_014314:576465:625492625492626406915Dehalogenimonas lykanthroporepellens BL-DC-9 chromosome, completephosphoribosylaminoimidazole-succinocarboxamide synthase6e-0754.7
NC_012803:1980955:200194920019492002896948Micrococcus luteus NCTC 2665, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase2e-0653.1
NC_007761:3564449:358285235828523583796945Rhizobium etli CFN 42, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase protein3e-0652.4
NC_007759:964000:984989984989985873885Syntrophus aciditrophicus SB, complete genomephosphoribosylaminoimidazole-succinocarboxamide synthase7e-0650.8