Pre_GI: BLASTP Hits

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Query: NC_010520:3120500:3120549 Clostridium botulinum A3 str. Loch Maree, complete genome

Start: 3120549, End: 3121442, Length: 894

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A3 str. Loch Maree was isolated from duck liver paste during a botulism outbreak at a hotel in the Scottish highlands in 1922. This was the first and worst outbreak of botulism in the United Kingdom (UK). This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014328:938393:951801951801952694894Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative Zn-dependent hydrolase, glyoxylase II family5e-108390
NC_014410:51711:757307573076626897Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,beta-lactamase domain protein1e-105382
NC_015555:49842:761827618277093912Thermoanaerobacterium xylanolyticum LX-11 chromosome, completebeta-lactamase domain protein6e-105380
NC_019970:35985:616176161762513897Thermoanaerobacterium thermosaccharolyticum M0795, complete genomeZn-dependent hydrolase, glyoxylase4e-104377
NC_015425:1867620:186980718698071870694888Clostridium botulinum BKT015925 chromosome, complete genomeZinc metallohydrolase, glyoxalase II family3e-95348
NC_015520:55710:584385843859331894Mahella australiensis 50-1 BON chromosome, complete genomebeta-lactamase2e-35149
NC_015681:401084:408519408519409412894Thermodesulfatator indicus DSM 15286 chromosome, complete genomebeta-lactamase domain-containing protein9e-31134
NC_014376:4369666:438738543873854388266882Clostridium saccharolyticum WM1 chromosome, complete genomebeta-lactamase domain-containing protein2e-30133
NC_011899:1021672:104297310429731043869897Halothermothrix orenii H 168, complete genomebeta-lactamase domain protein1e-28127
NC_014831:285759:288973288973289875903Thermaerobacter marianensis DSM 12885 chromosome, complete genomebeta-lactamase domain-containing protein9e-21100
NC_012491:4231469:425381742538174254725909Brevibacillus brevis NBRC 100599, complete genomehypothetical protein5e-1788.6
NC_019791:570923:577895577895578785891Caldisphaera lagunensis DSM 15908 chromosome, complete genomeZn-dependent hydrolase1e-1584
NC_014958:3207431:322763532276353228528894Deinococcus maricopensis DSM 21211 chromosome, complete genomebeta-lactamase domain-containing protein5e-1582
NC_015865:229883:249632249632250510879Thermococcus sp. 4557 chromosome, complete genomezinc-dependent hydrolase1e-1273.9
NC_015161:758929:772857772857773750894Deinococcus proteolyticus MRP chromosome, complete genomebeta-lactamase domain-containing protein2e-1273.2
NC_017276:85380:103851103851104672822Sulfolobus islandicus REY15A chromosome, complete genomebeta-lactamase5e-1272
NC_012632:87590:103092103092103991900Sulfolobus islandicus M.16.27 chromosome, complete genomebeta-lactamase domain-containing protein2e-1170.1
NC_012588:87592:101882101882102781900Sulfolobus islandicus M.14.25 chromosome, complete genomebeta-lactamase2e-1170.1
NC_013769:87582:101888101888102787900Sulfolobus islandicus L.D.8.5 chromosome, complete genomebeta-lactamase domain-containing protein3e-1169.3
NC_012589:87592:101882101882102781900Sulfolobus islandicus L.S.2.15, complete genomebeta-lactamase domain protein3e-1169.3
NC_012883:1283529:129054112905411291254714Thermococcus sibiricus MM 739, complete genomeHydrolase, metallo-beta-lactamase superfamily1e-1067.4
NC_013939:1417750:143629914362991436925627Deferribacter desulfuricans SSM1, complete genomemetallo-beta-lactamase family protein2e-0963.5
NC_014219:2509062:252091525209152521577663Bacillus selenitireducens MLS10 chromosome, complete genomebeta-lactamase domain protein4e-0858.9
NC_015518:1638262:165308516530851653711627Acidianus hospitalis W1 chromosome, complete genomebeta-lactamase domain-containing protein6e-0755.1
NC_015435:1180455:119334011933401194125786Metallosphaera cuprina Ar-4 chromosome, complete genomebeta-lactamase domain-containing protein7e-0755.1
NC_015518:761380:816021816021816818798Acidianus hospitalis W1 chromosome, complete genomebeta-lactamase domain-containing protein8e-0754.7
NC_004344:129798:142930142930143574645Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis,hypothetical protein4e-0652.4