Pre_GI: BLASTP Hits

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Query: NC_010520:2937981:2948683 Clostridium botulinum A3 str. Loch Maree, complete genome

Start: 2948683, End: 2949645, Length: 963

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A3 str. Loch Maree was isolated from duck liver paste during a botulism outbreak at a hotel in the Scottish highlands in 1922. This was the first and worst outbreak of botulism in the United Kingdom (UK). This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:2905138:291300329130032913965963Clostridium botulinum F str. 230613 chromosome, complete genomeflagellar hook-associated protein 36e-176616
NC_009699:2901497:291286529128652913827963Clostridium botulinum F str. Langeland chromosome, complete genomeflagellar hook-associated protein 36e-176616
NC_012658:2930244:294083729408372941799963Clostridium botulinum Ba4 str. 657 chromosome, complete genomeflagellar hook-associated protein 38e-167586
NC_009698:2727203:273960127396012740563963Clostridium botulinum A str. Hall chromosome, complete genomeflagellar hook-associated protein 34e-166583
NC_009697:2790277:280267528026752803637963Clostridium botulinum A str. ATCC 19397 chromosome, completeflagellar hook-associated protein 34e-166583
NC_009495:2876865:288926328892632890225963Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeflagellar hook-associated protein 34e-166583
NC_012563:3090954:310335231033523104314963Clostridium botulinum A2 str. Kyoto, complete genomeflagellar hook-associated protein 34e-166583
NC_010516:2900057:290832629083262909288963Clostridium botulinum B1 str. Okra, complete genomeflagellar hook-associated protein 31e-164579
NC_004557:1826977:183441918344191835369951Clostridium tetani E88, complete genomeflagellar hook-associated protein 39e-86317
NC_008593:1060548:108462510846251085602978Clostridium novyi NT, complete genomeflagellar hook-associated protein 3, putative2e-85316
NC_021182:2921000:2933008293300829340421035Clostridium pasteurianum BC1, complete genomeflagellar hook-associated protein 34e-72271
NC_009617:4946000:495102849510284952011984Clostridium beijerinckii NCIMB 8052 chromosome, complete genomeflagellar hook-associated protein 33e-66252
NC_016012:561687:569611569611570582972Candidatus Arthromitus sp. SFB-rat-Yit, complete genomeflagellar hook-associated protein 32e-62239
NC_015913:624859:629998629998630969972Candidatus Arthromitus sp. SFB-mouse-Japan, complete genomeflagellar hook-associated protein1e-61236
NC_015425:1207314:1215947121594712173711425Clostridium botulinum BKT015925 chromosome, complete genomeputative flagellar hook-associated protein 33e-38159
NC_007644:779376:783381783381784298918Moorella thermoacetica ATCC 39073, complete genomeFlagellin-like2e-37156
NC_009633:760872:775190775190776146957Alkaliphilus metalliredigens QYMF chromosome, complete genomeflagellar hook-associated protein 32e-37156
NC_014652:1091610:109161010916101092557948Caldicellulosiruptor hydrothermalis 108 chromosome, completeflagellar hook-associated protein 34e-37155
NC_009454:2201987:221826022182602219162903Pelotomaculum thermopropionicum SI, complete genomeflagellar hook-associated protein FlgL1e-35150
NC_020291:4944835:4988864498886449900571194Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomeflagellar hook-associated protein 31e-34147
NC_011899:1807365:182964518296451830550906Halothermothrix orenii H 168, complete genomeflagellar hook-associated protein 31e-34147
NC_017179:281069:303547303547304479933Clostridium difficile BI1, complete genomeflagellar hook-associated protein4e-33142
NC_017295:2286911:2301355230135523026321278Clostridium acetobutylicum EA 2018 chromosome, complete genomeFlagellin3e-32139
NC_004193:2553630:256289125628912563772882Oceanobacillus iheyensis HTE831, complete genomeflagellar hook-associated protein5e-32138
NC_015391:2059191:209593620959362096835900Carnobacterium sp. 17-4 chromosome, complete genomeflagellar hook-associated protein FlgL1e-31137
NC_010723:801215:8053698053698065771209Clostridium botulinum E3 str. Alaska E43, complete genomeflagellar hook-associated protein 32e-31136
NC_012793:3035978:304447430444743045379906Geobacillus sp. WCH70, complete genomeflagellar hook-associated protein 32e-31136
NC_014831:218696:220519220519221406888Thermaerobacter marianensis DSM 12885 chromosome, complete genomeflagellar hook-associated protein 33e-31136
NC_010674:828191:8281918281918293991209Clostridium botulinum B str. Eklund 17B, complete genomeflagellar hook-associated protein 35e-31135
NC_014098:3030274:305166130516613052551891Bacillus tusciae DSM 2912 chromosome, complete genomeflagellar hook-associated protein 33e-30132
NC_006510:3133965:315619931561993157092894Geobacillus kaustophilus HTA426, complete genomeflagellar hook-associated protein3e-30132
NC_007503:861668:861668861668862531864Carboxydothermus hydrogenoformans Z-2901, complete genomeflagellar hook-associated protein 35e-30131
NC_014915:3259440:328194332819433282836894Geobacillus sp. Y412MC52 chromosome, complete genomeflagellar hook-associated protein 37e-30131
NC_020134:2772500:277782127778212778732912Clostridium stercorarium subsp. stercorarium DSM 8532, completeflagellar hook-associated protein 39e-30130
NC_016935:75186:102835102835103731897Paenibacillus mucilaginosus 3016 chromosome, complete genomeflagellar hook-associated protein 31e-29130
NC_015690:75223:102808102808103698891Paenibacillus mucilaginosus KNP414 chromosome, complete genomeflagellar hook-associated protein 31e-29130
NC_010718:2337209:237219523721952373181987Natranaerobius thermophilus JW/NM-WN-LF, complete genomeflagellar hook-associated protein 33e-29129
NC_015660:391627:391627391627392541915Geobacillus thermoglucosidasius C56-YS93 chromosome, completeflagellar hook-associated protein 35e-29128
NC_019978:2260395:2275519227551922767031185Halobacteroides halobius DSM 5150, complete genomeflagellar hook-associated protein 38e-29127
NC_014650:376070:376070376070376966897Geobacillus sp. Y4.1MC1 chromosome, complete genomeflagellar hook-associated protein 31e-28127
NC_012914:6583000:660351866035186604477960Paenibacillus sp. JDR-2, complete genomeflagellar hook-associated protein 32e-28126
NC_011567:2556915:255819625581962559068873Anoxybacillus flavithermus WK1, complete genomeFlagellar hook-associated protein3e-26119
NC_009012:2661795:266906026690602669968909Clostridium thermocellum ATCC 27405, complete genomeflagellar hook-associated protein 33e-26119
NC_010337:748467:771320771320772249930Heliobacterium modesticaldum Ice1, complete genomeflagellar hook-associated protein 3, putative5e-26118
NC_019897:128610:176492176492177400909Thermobacillus composti KWC4 chromosome, complete genomeflagellar hook-associated protein 38e-25114
NC_014328:1046958:1062801106280110642071407Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative flagellar hook-associated protein6e-24111
NC_013406:6568273:658550265855026586398897Paenibacillus sp. Y412MC10 chromosome, complete genomeflagellar hook-associated protein 34e-22105
NC_017195:3426000:343625734362573437153897Bacillus subtilis subsp. subtilis str. RO-NN-1 chromosome, completeflagellar hook-associated protein 37e-22104
NC_009664:570768:585496585496586404909Kineococcus radiotolerans SRS30216, complete genomeflagellar hook-associated protein 37e-22104
NC_019896:577594:586765586765587661897Bacillus subtilis subsp. subtilis str. BSP1 chromosome, completeFlagellar hook-associated protein1e-21103
NC_016641:945284:953016953016953924909Paenibacillus terrae HPL-003 chromosome, complete genomeflagellin2e-21103
NC_013093:2599591:261417626141762615054879Actinosynnema mirum DSM 43827, complete genomeflagellar hook-associated protein 34e-21102
NC_013205:2610956:264604526460452647022978Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446,flagellin domain protein2e-1790.1
NC_014829:3877701:3883031388303138842151185Bacillus cellulosilyticus DSM 2522 chromosome, complete genomeflagellar hook-associated protein 33e-1686.3
NC_015589:1240197:1245694124569412467221029Desulfotomaculum ruminis DSM 2154 chromosome, complete genomeflagellar hook-associated protein 36e-1685.1
NC_014032:3330596:334731233473123348274963Salinibacter ruber M8 chromosome, complete genomeflagellar hook-associated protein FlgL9e-1684.3
NC_007517:480303:484210484210485094885Geobacter metallireducens GS-15, complete genomeFlagellin-like2e-1583.2
NC_006177:3192500:320079532007953201676882Symbiobacterium thermophilum IAM 14863, complete genomeflagellar-hook associated protein2e-1480.1
NC_013522:698114:7011627011627041883027Thermanaerovibrio acidaminovorans DSM 6589, complete genomeflagellin domain protein1e-1377.4
NC_018664:239000:2513482513482528411494Clostridium acidurici 9a chromosome, complete genomeflagellar hook-associated protein 32e-1376.6
NC_013791:1082951:1101117110111711028381722Bacillus pseudofirmus OF4 chromosome, complete genomeflagellar hook-associated protein 3 (HAP3)4e-1375.9
NC_009922:2721343:2726589272658927279051317Alkaliphilus oremlandii OhILAs, complete genomeflagellar hook-associated protein 32e-1170.1
NC_016584:4363382:4377886437788643792621377Desulfosporosinus orientis DSM 765 chromosome, complete genomeflagellar hook-associated protein 32e-1170.1
NC_012880:1765920:181760618176061818544939Dickeya dadantii Ech703, complete genomeflagellar hook-associated protein 33e-1169.7
NC_013223:724394:724394724394725272879Desulfohalobium retbaense DSM 5692, complete genomeflagellar hook-associated protein 38e-1168.2
NC_009831:66518:707107071071627918Shewanella sediminis HAW-EB3, complete genomeflagellar hook-associated protein 32e-1067
NC_009348:381752:381752381752382651900Aeromonas salmonicida subsp. salmonicida A449, complete genomelateral flagellar hook-associated protein, LfgL2e-1066.6
NC_015172:1075592:1085304108530410866801377Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomeflagellar hook-associated protein 34e-1065.5
NC_008011:924392:9316339316339332101578Lawsonia intracellularis PHE/MN1-00, complete genomeFlagellin and related hook-associated proteins7e-1065.1
NC_007759:1356439:1377134137713413783451212Syntrophus aciditrophicus SB, complete genomeflagellin and related hook-associated proteins7e-0961.6
NC_005085:4157257:417967341796734180521849Chromobacterium violaceum ATCC 12472, complete genomeflagellin1e-0757.4
NC_015318:290849:3078103078103105122703Hippea maritima DSM 10411 chromosome, complete genomeflagellin domain-containing protein2e-0756.6
NC_012779:2281700:2299661229966123007311071Edwardsiella ictaluri 93-146, complete genomeflagellin7e-0755.1
NC_009715:873280:8874728874728896942223Campylobacter curvus 525.92 chromosome, complete genomelagellar hook-associated protein FlgL7e-0651.6
NC_014387:605711:6162596162596183702112Butyrivibrio proteoclasticus B316 chromosome 1, complete genomeflagellar hook-associated protein FlgL9e-0651.2