Pre_GI: BLASTP Hits

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Query: NC_010520:2668702:2689232 Clostridium botulinum A3 str. Loch Maree, complete genome

Start: 2689232, End: 2690461, Length: 1230

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A3 str. Loch Maree was isolated from duck liver paste during a botulism outbreak at a hotel in the Scottish highlands in 1922. This was the first and worst outbreak of botulism in the United Kingdom (UK). This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012658:2641446:2682121268212126833501230Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein0726
NC_009698:2450606:2471150247115024723791230Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein0719
NC_009697:2478261:2498805249880525000341230Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein0719
NC_009495:2606238:2626688262668826279171230Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein0719
NC_012563:2761570:2801073280107328023021230Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein0719
NC_009699:2654672:2675053267505326762821230Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein0713
NC_017297:2635892:2675202267520226764311230Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein0713
NC_010516:2594159:2614734261473426159631230Clostridium botulinum B1 str. Okra, complete genomehypothetical protein0709
NC_014964:1309845:1326859132685913280641206Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completehypothetical protein6e-68258
NC_018664:1729794:1730954173095417321261173Clostridium acidurici 9a chromosome, complete genomeprotein of unknown function DUF7959e-67254
NC_017179:1239991:1241645124164512429251281Clostridium difficile BI1, complete genomehypothetical protein5e-65248
NC_013315:1230214:1231868123186812331481281Clostridium difficile CD196 chromosome, complete genomehypothetical protein5e-65248
NC_013316:1225797:1229484122948412307641281Clostridium difficile R20291, complete genomehypothetical protein5e-65248
NC_014624:2668157:2684487268448726857281242Eubacterium limosum KIST612 chromosome, complete genomehypothetical protein3e-55216
NC_019978:1410041:1428222142822214295111290Halobacteroides halobius DSM 5150, complete genomeputative nucleotidyltransferase2e-51203
NC_000853:1480478:1509521150952115107771257Thermotoga maritima MSB8, complete genomehypothetical protein6e-51201
NC_015437:1038476:1050469105046910517281260Selenomonas sputigena ATCC 35185 chromosome, complete genomeprotein of unknown function DUF7955e-47188
NC_014622:2114244:2122715212271521239501236Paenibacillus polymyxa SC2 chromosome, complete genomehypothetical protein9e-47187
NC_014483:1954856:1963308196330819645431236Paenibacillus polymyxa E681 chromosome, complete genomePredicted nucleotidyltransferase1e-46187
NC_015873:2260048:2262073226207322632841212Megasphaera elsdenii DSM 20460, complete genomeUPF0348 protein HMPREF0889_15403e-38159
NC_004461:813748:8170458170458181781134Staphylococcus epidermidis ATCC 12228, complete genomehypothetical protein2e-35150
NC_002976:707827:7111247111247122571134Staphylococcus epidermidis RP62A, complete genomehypothetical protein1e-34147
NC_006274:3805134:3825997382599738271781182Bacillus cereus E33L, complete genomehypothetical protein2e-33143
NC_011969:3657360:3678141367814136793221182Bacillus cereus Q1 chromosome, complete genomehypothetical protein8e-33141
NC_005957:3746891:3767726376772637689071182Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein3e-32139
NC_014335:3675456:3696323369632336975041182Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein7e-32138