Pre_GI: BLASTP Hits

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Query: NC_010520:2668702:2685196 Clostridium botulinum A3 str. Loch Maree, complete genome

Start: 2685196, End: 2685624, Length: 429

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A3 str. Loch Maree was isolated from duck liver paste during a botulism outbreak at a hotel in the Scottish highlands in 1922. This was the first and worst outbreak of botulism in the United Kingdom (UK). This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012658:2641446:267808326780832678511429Clostridium botulinum Ba4 str. 657 chromosome, complete genomePrdA domain-containing protein7e-58222
NC_010516:2594159:261069926106992611127429Clostridium botulinum B1 str. Okra, complete genomePrdA domain protein1e-57221
NC_017297:2635892:267116626711662671594429Clostridium botulinum F str. 230613 chromosome, complete genomePrdA domain protein4e-57219
NC_009699:2654672:267101826710182671446429Clostridium botulinum F str. Langeland chromosome, complete genomePrdA domain-containing protein4e-57219
NC_012563:2761570:279703827970382797466429Clostridium botulinum A2 str. Kyoto, complete genomePrdA domain protein9e-57218
NC_009495:2606238:262265326226532623081429Clostridium botulinum A str. ATCC 3502 chromosome, complete genome9e-57218
NC_009697:2478261:249477024947702495198429Clostridium botulinum A str. ATCC 19397 chromosome, completePrdA domain-containing protein9e-57218
NC_009698:2450606:246711524671152467543429Clostridium botulinum A str. Hall chromosome, complete genomePrdA domain-containing protein9e-57218
NC_010516:2594159:260661326066132607275663Clostridium botulinum B1 str. Okra, complete genomehypothetical protein9e-34142
NC_012563:2761570:279293727929372793599663Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein9e-34142
NC_010520:2668702:268110926811092681771663Clostridium botulinum A3 str. Loch Maree, complete genomehypothetical protein2e-33141
NC_009495:2606238:261856726185672619229663Clostridium botulinum A str. ATCC 3502 chromosome, complete genome1e-33141
NC_009699:2654672:266709226670922667754663Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein1e-33141
NC_017297:2635892:266724026672402667902663Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein1e-33141
NC_009697:2478261:249068424906842491346663Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein1e-33141
NC_009698:2450606:246302924630292463691663Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein1e-33141
NC_009697:2478261:2486591248659124887022112Clostridium botulinum A str. ATCC 19397 chromosome, completeD-proline reductase subunit PrdA4e-33140
NC_009698:2450606:2458936245893624610472112Clostridium botulinum A str. Hall chromosome, complete genomeD-proline reductase subunit PrdA4e-33140
NC_009495:2606238:2614478261447826165862109Clostridium botulinum A str. ATCC 3502 chromosome, complete genomesubunit of proline reductase3e-33140
NC_012563:2761570:2788847278884727909552109Clostridium botulinum A2 str. Kyoto, complete genomeD-proline reductase, PrdA proprotein3e-33140
NC_009699:2654672:2663002266300226651102109Clostridium botulinum F str. Langeland chromosome, complete genomeD-proline reductase subunit PrdA3e-33140
NC_017297:2635892:2663152266315226652602109Clostridium botulinum F str. 230613 chromosome, complete genomeputative D-proline reductase, PrdA proprotein3e-33140
NC_012658:2641446:2669909266990926720202112Clostridium botulinum Ba4 str. 657 chromosome, complete genomeD-proline reductase, PrdA proprotein3e-33140
NC_010516:2594159:2602523260252326046312109Clostridium botulinum B1 str. Okra, complete genomeputative D-proline reductase, PrdA proprotein2e-33140
NC_010520:2668702:2677019267701926791302112Clostridium botulinum A3 str. Loch Maree, complete genomeputative D-proline reductase, PrdA proprotein6e-33139
NC_012658:2641446:2654366265436626564802115Clostridium botulinum Ba4 str. 657 chromosome, complete genomeD-proline reductase, PrdA proprotein1e-32138
NC_010516:2567911:2584352258435225864662115Clostridium botulinum B1 str. Okra, complete genomeputative D-proline reductase, PrdA proprotein5e-32136
NC_012563:2761570:2770649277064927727632115Clostridium botulinum A2 str. Kyoto, complete genomeD-proline reductase, PrdA proprotein5e-32136
NC_009699:2635745:2644821264482126469352115Clostridium botulinum F str. Langeland chromosome, complete genomeD-proline reductase subunit PrdA5e-32136
NC_017297:2635892:2644968264496826470822115Clostridium botulinum F str. 230613 chromosome, complete genomeD-proline reductase subunit PrdA5e-32136
NC_012658:2641446:267399426739942674656663Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein5e-32136
NC_014614:2333890:2342523234252323444121890Clostridium sticklandii, complete genomeD-proline reductase proprotein prdA [Contains: D-proline reductase subunit beta (D-proline reductase 45 kDa subunit); D-proline reductase subunit alph1e-22105
NC_017179:3621306:3630325363032536322051881Clostridium difficile BI1, complete genomeproline reductase subunit proprotein1e-1995.1
NC_013315:3613288:3622307362230736241871881Clostridium difficile CD196 chromosome, complete genomeproline reductase subunit proprotein1e-1995.1
NC_009089:3782000:3793823379382337957031881Clostridium difficile 630, complete genomeproline reductase subunit proprotein1e-1995.1