Pre_GI: BLASTP Hits

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Query: NC_010520:2668702:2679152 Clostridium botulinum A3 str. Loch Maree, complete genome

Start: 2679152, End: 2679328, Length: 177

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A3 str. Loch Maree was isolated from duck liver paste during a botulism outbreak at a hotel in the Scottish highlands in 1922. This was the first and worst outbreak of botulism in the United Kingdom (UK). This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012658:2641446:267204226720422672218177Clostridium botulinum Ba4 str. 657 chromosome, complete genome2e-28124
NC_009698:2450606:246107224610722461248177Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein2e-27120
NC_017297:2635892:266528526652852665461177Clostridium botulinum F str. 230613 chromosome, complete genomeputative electron transport protein7e-27119
NC_009495:2606238:261661126166112616787177Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein7e-27119
NC_010516:2594159:260465626046562604832177Clostridium botulinum B1 str. Okra, complete genomehypothetical protein7e-27119
NC_012563:2761570:279098027909802791156177Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein1e-26118
NC_010516:2567911:258649825864982586668171Clostridium botulinum B1 str. Okra, complete genomehypothetical protein8e-25112
NC_012563:2761570:277279627727962772966171Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein8e-25112
NC_012658:2641446:265651226565122656682171Clostridium botulinum Ba4 str. 657 chromosome, complete genome8e-25112
NC_017297:2635892:264711726471172647287171Clostridium botulinum F str. 230613 chromosome, complete genomeputative electron transport protein8e-25112
NC_010520:2668702:2681811268181126831151305Clostridium botulinum A3 str. Loch Maree, complete genomeputative electron transport protein8e-2095.9
NC_010516:2594159:2607315260731526086191305Clostridium botulinum B1 str. Okra, complete genomeputative electron transport protein7e-2095.9
NC_009495:2606238:2619269261926926205731305Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeelectron transferring subunit of proline reductase7e-2095.9
NC_012658:2641446:2674696267469626760001305Clostridium botulinum Ba4 str. 657 chromosome, complete genomeputative electron transport protein7e-2095.9
NC_009699:2654672:2667794266779426690981305Clostridium botulinum F str. Langeland chromosome, complete genomeelectron transport protein7e-2095.9
NC_017297:2635892:2667942266794226692461305Clostridium botulinum F str. 230613 chromosome, complete genomeputative electron transport protein7e-2095.9
NC_009697:2478261:2491386249138624926901305Clostridium botulinum A str. ATCC 19397 chromosome, completeelectron transport protein7e-2095.9
NC_009698:2450606:2463731246373124650351305Clostridium botulinum A str. Hall chromosome, complete genomeelectron transport protein7e-2095.9
NC_012563:2761570:2793639279363927949431305Clostridium botulinum A2 str. Kyoto, complete genomeputative electron transport protein7e-2095.9
NC_010520:2668702:2685656268565626869661311Clostridium botulinum A3 str. Loch Maree, complete genomeputative electron transport protein7e-1889.4
NC_010516:2594159:2611158261115826124681311Clostridium botulinum B1 str. Okra, complete genomeputative electron transport protein7e-1889.4
NC_009699:2654672:2671477267147726727871311Clostridium botulinum F str. Langeland chromosome, complete genomeelectron transport protein7e-1889.4
NC_012563:2761570:2797497279749727988071311Clostridium botulinum A2 str. Kyoto, complete genomeputative electron transport protein7e-1889.4
NC_012658:2641446:2678542267854226798521311Clostridium botulinum Ba4 str. 657 chromosome, complete genomeputative electron transport protein7e-1889
NC_009698:2450606:2467574246757424688841311Clostridium botulinum A str. Hall chromosome, complete genomeelectron transport protein7e-1889
NC_009697:2478261:2495229249522924965391311Clostridium botulinum A str. ATCC 19397 chromosome, completeelectron transport protein7e-1889
NC_009495:2606238:2623112262311226244221311Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeelectron transferring subunit of proline reductase7e-1889
NC_017179:3621306:3635195363519536365081314Clostridium difficile BI1, complete genomeelectron transfer protein1e-1375.5
NC_013315:3613288:3627177362717736284901314Clostridium difficile CD196 chromosome, complete genomeelectron transfer protein1e-1375.5
NC_009089:3782000:3801552380155238028651314Clostridium difficile 630, complete genomeputative electron transfer protein1e-1375.5