Pre_GI: BLASTP Hits

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Query: NC_010520:2668702:2673312 Clostridium botulinum A3 str. Loch Maree, complete genome

Start: 2673312, End: 2674319, Length: 1008

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A3 str. Loch Maree was isolated from duck liver paste during a botulism outbreak at a hotel in the Scottish highlands in 1922. This was the first and worst outbreak of botulism in the United Kingdom (UK). This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:2635892:2659443265944326604501008Clostridium botulinum F str. 230613 chromosome, complete genomeproline racemase0654
NC_009699:2654672:2659294265929426603011008Clostridium botulinum F str. Langeland chromosome, complete genomeproline racemase0654
NC_009698:2450606:2455229245522924562361008Clostridium botulinum A str. Hall chromosome, complete genomeproline racemase0654
NC_009697:2478261:2482884248288424838911008Clostridium botulinum A str. ATCC 19397 chromosome, completeproline racemase0654
NC_009495:2606238:2610771261077126117781008Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeproline racemase0654
NC_012563:2761570:2785140278514027861471008Clostridium botulinum A2 str. Kyoto, complete genomeproline racemase0654
NC_010516:2594159:2598816259881625998231008Clostridium botulinum B1 str. Okra, complete genomeproline racemase0654
NC_012658:2641446:2666201266620126672081008Clostridium botulinum Ba4 str. 657 chromosome, complete genomeproline racemase0652
NC_009089:3782000:3789848378984837908551008Clostridium difficile 630, complete genomeputative proline racemase1e-113409
NC_013315:3613288:3618332361833236193391008Clostridium difficile CD196 chromosome, complete genomeproline racemase1e-113409
NC_017179:3621306:3626350362635036273571008Clostridium difficile BI1, complete genomeproline racemase1e-113409
NC_014614:2333890:2339192233919223401991008Clostridium sticklandii, complete genomeProline racemase A precursor (TcPRACA) (TcPA45-A) (rTcPA45)2e-111402
NC_008148:2231045:2270834227083422718471014Rubrobacter xylanophilus DSM 9941, complete genomeproline racemase1e-84313
NC_014815:4621552:4653973465397346549741002Micromonospora sp. L5 chromosome, complete genomeproline racemase2e-82306
NC_016641:2773757:2782839278283927838401002Paenibacillus terrae HPL-003 chromosome, complete genomeproline racemase3e-78292
NC_013524:1207845:1226906122690612279071002Sphaerobacter thermophilus DSM 20745 chromosome 2, complete genomeProline racemase1e-74280
NC_013947:4363250:4381353438135343823541002Stackebrandtia nassauensis DSM 44728 chromosome, complete genomeProline racemase2e-73276
NC_011883:2031222:2034668203466820356751008Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774,proline racemase4e-68258
NC_008148:2231045:2259325225932522603321008Rubrobacter xylanophilus DSM 9941, complete genomeproline racemase8e-67254
NC_016745:546249:5491605491605501611002Oceanimonas sp. GK1 chromosome, complete genomehydroxyproline-2-epimerase4e-62238
NC_010170:1324758:132581013258101326808999Bordetella petrii, complete genomehypothetical protein2e-61236
NC_007802:1484641:1498924149892414999641041Jannaschia sp. CCS1, complete genomeproline racemase2e-60233
NC_016002:2652500:2654016265401626550801065Pseudogulbenkiania sp. NH8B, complete genomeproline racemase1e-58227
NC_014934:4834000:4835848483584848368551008Cellulophaga algicola DSM 14237 chromosome, complete genomeproline racemase3e-58225
NC_003305:1035342:105673110567311057729999Agrobacterium tumefaciens str. C58 chromosome linear, completehypothetical protein2e-55216
NC_016642:1913432:1923747192374719247721026Pseudovibrio sp. FO-BEG1 chromosome, complete genomeproline racemase5e-53208
NC_012483:3731542:379978937997893800736948Acidobacterium capsulatum ATCC 51196, complete genomeputative proline racemase3e-51202
NC_015379:4426827:443879244387924439715924Pseudomonas brassicacearum subsp. brassicacearum NFM421 chromosome,4-hydroxyproline epimerase2e-51202
NC_020829:809457:812039812039812983945Pseudomonas denitrificans ATCC 13867, complete genomeproline racemase2e-49196
NC_020064:1854589:185364218536421854592951Serratia marcescens FGI94, complete genomeproline racemase8e-48191
NC_011894:4013830:403950240395024040473972Methylobacterium nodulans ORS 2060, complete genomeproline racemase4e-47188
NC_010511:4258000:427531442753144276285972Methylobacterium sp. 4-46 chromosome, complete genomeproline racemase4e-46185
NC_017506:923500:9359189359189369791062Marinobacter adhaerens HP15 chromosome, complete genomeproline racemase1e-43177
NC_014166:1179335:1184831118483111858681038Arcobacter nitrofigilis DSM 7299 chromosome, complete genomeproline racemase2e-37156
NC_011894:4013830:404885040488504049818969Methylobacterium nodulans ORS 2060, complete genomeproline racemase1e-36154
NC_014841:131308:1482791482791493431065Pantoea sp. At-9b plasmid pPAT9B04, complete sequenceProline racemase2e-29130