Pre_GI: BLASTP Hits

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Query: NC_010520:2668702:2668702 Clostridium botulinum A3 str. Loch Maree, complete genome

Start: 2668702, End: 2669778, Length: 1077

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A3 str. Loch Maree was isolated from duck liver paste during a botulism outbreak at a hotel in the Scottish highlands in 1922. This was the first and worst outbreak of botulism in the United Kingdom (UK). This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:2635892:2654820265482026558961077Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein0688
NC_009699:2654672:2654672265467226557481077Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein0687
NC_012563:2761570:2780509278050927815851077Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein0687
NC_009495:2606238:2606238260623826073141077Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein0686
NC_009697:2478261:2478261247826124793371077Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein0686
NC_009698:2450606:2450606245060624516821077Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein0686
NC_010516:3466000:3466241346624134673171077Clostridium botulinum B1 str. Okra, complete genomehypothetical protein0686
NC_012658:2641446:2661595266159526626711077Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein0684
NC_010516:2594159:2594159259415925952351077Clostridium botulinum B1 str. Okra, complete genomehypothetical protein0683
NC_012563:2761570:2779347277934727804321086Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein4e-107388
NC_012658:2641446:2660441266044126615261086Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein7e-107387
NC_010516:3466000:3467394346739434684791086Clostridium botulinum B1 str. Okra, complete genomehypothetical protein5e-107387
NC_017297:2635892:2653666265366626547511086Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein2e-106385
NC_009699:2635745:2653518265351826546031086Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein2e-106385
NC_016894:1092005:1110356111035611114621107Acetobacterium woodii DSM 1030 chromosome, complete genomehypothetical protein1e-90333
NC_015562:1460124:1460124146012414613861263Methanotorris igneus Kol 5 chromosome, complete genomehypothetical protein9e-39160
NC_014297:1100997:1116559111655911178091251Halalkalicoccus jeotgali B3 chromosome, complete genomeLOR/SDH bifunctional protein2e-38160
NC_003551:812939:8196248196248208621239Methanopyrus kandleri AV19, complete genomehypothetical protein2e-38159
NC_015847:1261276:1292357129235712935981242Methanococcus maripaludis XI chromosome, complete genomeLOR/SDH bifunctional protein conserved domain-containing protein6e-38158
NC_009135:330628:3327263327263339731248Methanococcus maripaludis C5, complete genomeLOR/SDH bifunctional enzyme conserved domain protein3e-37156
NC_009637:438037:4741784741784754251248Methanococcus maripaludis C7 chromosome, complete genomeLOR/SDH bifunctional protein3e-37155
NC_013887:407771:4137434137434149631221Methanocaldococcus sp. FS406-22 chromosome, complete genomeLOR/SDH bifunctional protein conserved domain protein7e-35148
NC_015320:273979:2822692822692832861018Archaeoglobus veneficus SNP6 chromosome, complete genome3e-0860.1