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Query: NC_010520:2101515:2126607 Clostridium botulinum A3 str. Loch Maree, complete genome

Start: 2126607, End: 2128403, Length: 1797

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A3 str. Loch Maree was isolated from duck liver paste during a botulism outbreak at a hotel in the Scottish highlands in 1922. This was the first and worst outbreak of botulism in the United Kingdom (UK). This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014377:1227850:1250739125073912525261788Thermosediminibacter oceani DSM 16646 chromosome, complete genomephage uncharacterized protein2e-99363
NC_021182:3347076:3364535336453533662861752Clostridium pasteurianum BC1, complete genomehypothetical protein1e-95350
NC_010516:2328288:2328288232828823300211734Clostridium botulinum B1 str. Okra, complete genomehypothetical protein1e-95350
NC_021182:4367736:4369180436918043709551776Clostridium pasteurianum BC1, complete genomehypothetical protein5e-91335
NC_021182:2765000:2782482278248227842751794Clostridium pasteurianum BC1, complete genomehypothetical protein3e-67256
NC_015172:515557:5314145314145331741761Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomephage uncharacterized protein3e-23110
NC_015172:2628128:2657032265703226587921761Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomephage uncharacterized protein3e-23110
NC_015172:2986867:3011559301155930133191761Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomephage uncharacterized protein3e-23110
NC_015172:3160249:3185779318577931875391761Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomephage uncharacterized protein3e-23110
NC_009454:2292716:2295172229517222968901719Pelotomaculum thermopropionicum SI, complete genomehypothetical protein2e-1790.9
NC_018867:1407163:1424327142432714259281602Dehalobacter sp. CF chromosome, complete genomephage uncharacterized protein (putative large terminase), C-terminal domain protein4e-1687
NC_016641:2587000:2606685260668526082351551Paenibacillus terrae HPL-003 chromosome, complete genomehypothetical protein1e-1482
NC_012440:1709416:1745224174522417467801557Persephonella marina EX-H1, complete genomehypothetical protein3e-1170.5
NC_016641:2618587:262646426264642627357894Paenibacillus terrae HPL-003 chromosome, complete genomehypothetical protein6e-1169.7
NC_011772:2763863:2784068278406827857831716Bacillus cereus G9842, complete genomephage protein1e-1068.6
NC_017192:1885457:1904392190439219061281737Arcobacter sp. L, complete genomehypothetical protein2e-1068.2
NC_009714:224325:2389872389872404891503Campylobacter hominis ATCC BAA-381, complete genomehypothetical protein4e-1067
NC_017208:1831918:1866282186628218679971716Bacillus thuringiensis serovar chinensis CT-43 chromosome, completePhage protein4e-1067
NC_004722:1804788:1834922183492218366371716Bacillus cereus ATCC 14579, complete genomePhage protein5e-0963.5
NC_009850:1651410:1672570167257016742911722Arcobacter butzleri RM4018, complete genomephage uncharacterized protein1e-0862