Pre_GI: BLASTP Hits

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Query: NC_010520:2101515:2124613 Clostridium botulinum A3 str. Loch Maree, complete genome

Start: 2124613, End: 2125335, Length: 723

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A3 str. Loch Maree was isolated from duck liver paste during a botulism outbreak at a hotel in the Scottish highlands in 1922. This was the first and worst outbreak of botulism in the United Kingdom (UK). This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010516:2305110:232628523262852327007723Clostridium botulinum B1 str. Okra, complete genomehypothetical protein2e-129461
NC_010674:1986000:200624920062492007130882Clostridium botulinum B str. Eklund 17B, complete genomehypothetical protein6e-26117
NC_021182:2765000:278014027801402781042903Clostridium pasteurianum BC1, complete genomephage putative head morphogenesis protein, SPP1 gp7 family4e-22104
NC_014377:1227850:124857012485701249451882Thermosediminibacter oceani DSM 16646 chromosome, complete genomephage head morphogenesis protein, SPP1 gp7 family1e-1893.6
NC_013891:1639694:164959016495901650354765Listeria seeligeri serovar 1/2b str. SLCC3954, complete genomephage minor head protein, putative6e-1477.8
NC_014376:1472304:1494842149484214964161575Clostridium saccharolyticum WM1 chromosome, complete genomephage head morphogenesis protein, SPP1 gp7 family7e-1270.9
NC_015519:1081539:1098996109899611005371542Tepidanaerobacter sp. Re1 chromosome, complete genomephage head morphogenesis protein, SPP1 gp7 family4e-1168.2
NC_020134:420500:4352584352584365891332Clostridium stercorarium subsp. stercorarium DSM 8532, completephage head morphogenesis protein, SPP1 gp7 family7e-1167.8
NC_017353:887581:906346906346907296951Staphylococcus lugdunensis N920143, complete genomephage Mu protein F-like protein3e-1065.9
NC_016077:1388775:1409072140907214108771806Acidaminococcus intestini RyC-MR95 chromosome, complete genomeputative head protein2e-0962.8
NC_009012:2927793:2948505294850529499141410Clostridium thermocellum ATCC 27405, complete genomephage putative head morphogenesis protein, SPP1 gp7 family2e-0962.8
NC_013741:1275555:1282796128279612839921197Archaeoglobus profundus DSM 5631, complete genomephage head morphogenesis protein, SPP1 gp7 family3e-0858.5
NC_014554:2159782:2162547216254721642321686Lactobacillus plantarum subsp. plantarum ST-III chromosome,prophage minor head protein1e-0757
NC_020450:1726234:1735896173589617370021107Lactococcus lactis subsp. lactis IO-1 DNA, complete genomeNAD+--asparagine ADP-ribosyltransferase7e-0754.3
NC_015930:1105882:1126065112606511271621098Lactococcus garvieae ATCC 49156, complete genomephage minor head protein1e-0653.9
NC_012466:1754388:1764250176425017658331584Streptococcus pneumoniae JJA, complete genomephage putative head morphogenesis protein, SPP1 gp7 family2e-0652.8
NC_012658:1810640:1830909183090918319311023Clostridium botulinum Ba4 str. 657 chromosome, complete genomephage head morphogenesis protein, SPP1 gp7 family2e-0652.8
NC_008530:646207:6599656599656614971533Lactobacillus gasseri ATCC 33323, complete genomePhage Mu protein F like protein3e-0652.4
NC_015601:627217:6469536469536483081356Erysipelothrix rhusiopathiae str. Fujisawa, complete genomephage head morphogenesis protein, SPP1 gp7 family3e-0652.4
NC_014498:1983740:2009696200969620112791584Streptococcus pneumoniae 670-6B chromosome, complete genomephage putative head morphogenesis protein, SPP1 gp7 family4e-0652
NC_017297:2531750:2548457254845725494791023Clostridium botulinum F str. 230613 chromosome, complete genomephage head morphogenesis protein4e-0652
NC_014925:578759:6030636030636044121350Staphylococcus pseudintermedius HKU10-03 chromosome, completehypothetical protein4e-0651.6