Pre_GI: BLASTP Hits

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Query: NC_010520:2101515:2114844 Clostridium botulinum A3 str. Loch Maree, complete genome

Start: 2114844, End: 2115521, Length: 678

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A3 str. Loch Maree was isolated from duck liver paste during a botulism outbreak at a hotel in the Scottish highlands in 1922. This was the first and worst outbreak of botulism in the United Kingdom (UK). This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_020291:795500:824893824893825561669Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomephage putative tail component7e-42170
NC_008593:1362218:137177813717781372461684Clostridium novyi NT, complete genomeconserved phage-related protein3e-34145
NC_010723:2269372:227265022726502273324675Clostridium botulinum E3 str. Alaska E43, complete genomeputative phage tail component5e-34144
NC_015425:1295261:132121613212161321896681Clostridium botulinum BKT015925 chromosome, complete genomephage-like protein3e-33141
NC_010674:2328307:233610623361062336783678Clostridium botulinum B str. Eklund 17B, complete genomeputative phage tail component2e-31135
NC_020291:1122282:113714911371491137850702Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomephage-rlike protein1e-26119
NC_011773:549500:557944557944558621678Bacillus cereus AH820 chromosome, complete genomeGp13 protein2e-25115
NC_010674:950276:965214965214965930717Clostridium botulinum B str. Eklund 17B, complete genomeprophage pi2 protein 436e-22104
NC_008261:1787345:179485417948541795564711Clostridium perfringens ATCC 13124, complete genomeputative phage tail component1e-1893.2
NC_012471:781063:813226813226813933708Streptococcus equi subsp. equi 4047, complete genomephage protein2e-1685.9
NC_009332:1269000:127924312792431279950708Streptococcus pyogenes str. Manfredo chromosome, complete genomehypothetical protein2e-1685.5
NC_008024:572916:579195579195579902708Streptococcus pyogenes MGAS10750, complete genomephage protein2e-1685.5
NC_008022:556457:562018562018562725708Streptococcus pyogenes MGAS10270, complete genomephage protein2e-1685.5
NC_008021:531730:560741560741561448708Streptococcus pyogenes MGAS9429, complete genomephage protein2e-1685.5
NC_006086:987991:9996179996171000324708Streptococcus pyogenes MGAS10394, complete genomeunknown phage protein2e-1582.4
NC_002737:533291:559855559855560571717Streptococcus pyogenes M1 GAS, complete genomehypothetical protein2e-1582.4
NC_004070:1231883:124239212423921243108717Streptococcus pyogenes MGAS315, complete genomehypothetical protein3e-1582
NC_007296:1230614:123970512397051240421717Streptococcus pyogenes MGAS6180, complete genomephage protein3e-1582
NC_008022:1255210:126680312668031267519717Streptococcus pyogenes MGAS10270, complete genomephage protein3e-1582
NC_004606:623853:653777653777654493717Streptococcus pyogenes SSI-1, complete genomehypothetical protein3e-1582
NC_003485:1450045:146247114624711463187717Streptococcus pyogenes MGAS8232, complete genomehypothetical protein2e-1479.7
NC_006086:1329915:134208413420841342800717Streptococcus pyogenes MGAS10394, complete genomeunknown phage protein2e-1479.7
NC_003212:2592600:259472325947232595463741Listeria innocua Clip11262, complete genomehypothetical protein5e-1478.2
NC_014218:1663486:167891516789151679607693Arcanobacterium haemolyticum DSM 20595 chromosome, complete genomehypothetical protein8e-1477
NC_014246:1402500:143099214309921431678687Mobiluncus curtisii ATCC 43063 chromosome, complete genomehypothetical protein9e-1477
NC_004606:904323:908291908291908953663Streptococcus pyogenes SSI-1, complete genomehypothetical protein1e-1376.6
NC_021182:3525523:356016335601633560600438Clostridium pasteurianum BC1, complete genome2e-1375.9
NC_008555:1204000:123664712366471237387741Listeria welshimeri serovar 6b str. SLCC5334, complete genomeconserved phage-related protein3e-1375.1
NC_003485:602640:608575608575609318744Streptococcus pyogenes MGAS8232, complete genomehypothetical protein3e-1065.5
NC_014393:4775452:479400947940094794785777Clostridium cellulovorans 743B chromosome, complete genomephage tail component2e-0962.8
NC_013766:679906:7069587069587092012244Listeria monocytogenes 08-5578 chromosome, complete genomeminor structural protein GP751e-0653.5
NC_010337:2793667:282706228270622827835774Heliobacterium modesticaldum Ice1, complete genomephage tail component, n-terminal domain, putative6e-0651.2