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Query: NC_010520:121077:132168 Clostridium botulinum A3 str. Loch Maree, complete genome

Start: 132168, End: 133481, Length: 1314

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A3 str. Loch Maree was isolated from duck liver paste during a botulism outbreak at a hotel in the Scottish highlands in 1922. This was the first and worst outbreak of botulism in the United Kingdom (UK). This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012658:125500:1358861358861371391254Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein0709
NC_010516:127000:1381861381861394871302Clostridium botulinum B1 str. Okra, complete genomehypothetical protein0707
NC_012563:122000:1323411323411336301290Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein0701
NC_009699:122000:1332081332081345031296Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein0699
NC_009698:120119:1312101312101324991290Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein0699
NC_009697:120117:1312081312081324971290Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein0699
NC_009495:128000:1384051384051396941290Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein0699
NC_014328:180482:1986131986131998901278Clostridium ljungdahlii ATCC 49587 chromosome, complete genomehypothetical protein2e-118426
NC_016791:2983349:3011545301154530128551311Clostridium sp. BNL1100 chromosome, complete genomehypothetical protein5e-90331
NC_009486:1737703:1791817179181717930101194Thermotoga petrophila RKU-1 chromosome, complete genomehypothetical protein1e-84314
NC_011297:1357947:1369548136954813707081161Dictyoglomus thermophilum H-6-12, complete genomehypothetical protein1e-84313
NC_011661:1542335:1553921155392115550901170Dictyoglomus turgidum DSM 6724, complete genomeprotein of unknown function DUF1115e-83308
NC_014206:1618988:1631678163167816329131236Geobacillus sp. C56-T3 chromosome, complete genomehypothetical protein4e-82305
NC_006510:1995916:2005960200596020071951236Geobacillus kaustophilus HTA426, complete genomehypothetical protein4e-80298
NC_007503:1111457:1142854114285411440591206Carboxydothermus hydrogenoformans Z-2901, complete genomehypothetical protein4e-80298
NC_015573:649800:6665436665436677361194Desulfotomaculum kuznetsovii DSM 6115 chromosome, complete genomehypothetical protein3e-78292
NC_011768:3385719:3388750338875033899221173Desulfatibacillum alkenivorans AK-01, complete genomeprotein of unknown function DUF1112e-75283
NC_008009:2430509:2432517243251724339051389Acidobacteria bacterium Ellin345, complete genomeprotein of unknown function DUF1117e-66251
NC_013943:2857751:2876779287677928779391161Denitrovibrio acetiphilus DSM 12809 chromosome, complete genomehypothetical protein2e-51203
NC_016023:1874827:188254518825451883369825Bacillus coagulans 36D1 chromosome, complete genomehypothetical protein5e-50198
NC_014122:665684:6781076781076792251119Methanocaldococcus infernus ME chromosome, complete genomeprotein of unknown function DUF1111e-46187
NC_014624:1369642:137861213786121379340729Eubacterium limosum KIST612 chromosome, complete genomehypothetical protein1e-46187
NC_015565:2027279:205252320525232053311789Desulfotomaculum carboxydivorans CO-1-SRB chromosome, completehypothetical protein2e-46186
NC_012029:1654816:1675338167533816768161479Halorubrum lacusprofundi ATCC 49239 chromosome 1, complete genomeprotein of unknown function DUF1111e-43177
NC_014002:809816:8269898269898281731185Methanohalophilus mahii DSM 5219 chromosome, complete genomeprotein of unknown function DUF1113e-43176
NC_014507:1127115:113784011378401138601762Methanoplanus petrolearius DSM 11571 chromosome, complete genomehypothetical protein1e-32141
NC_017297:122383:133470133470133679210Clostridium botulinum F str. 230613 chromosome, complete genome2e-27123
NC_016023:1874827:188337418833741883844471Bacillus coagulans 36D1 chromosome, complete genomehypothetical protein4e-27122
NC_009634:299327:326766326766327512747Methanococcus vannielii SB chromosome, complete genomehypothetical protein2e-26120
NC_021184:592501:595397595397595861465Desulfotomaculum gibsoniae DSM 7213, complete genome4e-25116