Pre_GI: BLASTP Hits

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Query: NC_010516:583870:599535 Clostridium botulinum B1 str. Okra, complete genome

Start: 599535, End: 600539, Length: 1005

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:564727:5830295830295840331005Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein4e-171600
NC_009699:564455:5827585827585837621005Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein4e-171600
NC_014410:2511753:251279125127912513744954Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,hypothetical protein7e-88323
NC_015499:1062359:1068573106857310696251053Thermodesulfobium narugense DSM 14796 chromosome, complete genomehypothetical protein2e-82305
NC_003366:2286083:2290351229035122913611011Clostridium perfringens str. 13, complete genomehypothetical protein2e-81302
NC_008261:2481500:2504207250420725052171011Clostridium perfringens ATCC 13124, complete genomehypothetical protein2e-81302
NC_008262:2169262:2173511217351121745211011Clostridium perfringens SM101, complete genomehypothetical protein2e-81302
NC_014328:938393:9496649496649506801017Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative exopolysaccharide biosynthesis protein3e-69262
NC_015873:238187:239948239948240892945Megasphaera elsdenii DSM 20460, complete genomehypothetical protein2e-63243
NC_019903:3048132:3065342306534230664361095Desulfitobacterium dichloroeliminans LMG P-21439 chromosome,exopolysaccharide biosynthesis protein7e-61234
NC_010723:915697:9368199368199378651047Clostridium botulinum E3 str. Alaska E43, complete genomehypothetical protein5e-53208
NC_016584:138348:159400159400160359960Desulfosporosinus orientis DSM 765 chromosome, complete genomeexopolysaccharide biosynthesis protein4e-43175
NC_016935:2069562:2074387207438720756131227Paenibacillus mucilaginosus 3016 chromosome, complete genomehypothetical protein5e-40165
NC_016584:138348:1574701574701593561887Desulfosporosinus orientis DSM 765 chromosome, complete genomeexopolysaccharide biosynthesis protein7e-40164
NC_015690:1542061:1546886154688615481121227Paenibacillus mucilaginosus KNP414 chromosome, complete genomehypothetical protein8e-40164
NC_014828:541874:5670555670555725925538Ethanoligenens harbinense YUAN-3 chromosome, complete genomeLPXTG-motif cell wall anchor domain protein1e-1377.4
NC_016609:1774259:180284218028421803768927Niastella koreensis GR20-10 chromosome, complete genomehypothetical protein5e-1168.9
NC_014377:1871333:1887649188764918906002952Thermosediminibacter oceani DSM 16646 chromosome, complete genomecopper amine oxidase domain protein4e-1065.9
NC_013061:1:128412842153870Pedobacter heparinus DSM 2366, complete genomehypothetical protein8e-1064.7
NC_015277:2283530:229737222973722298214843Sphingobacterium sp. 21 chromosome, complete genomehypothetical protein1e-0860.8
NC_004663:5099845:511694251169425117868927Bacteroides thetaiotaomicron VPI-5482, complete genomehypothetical protein7e-0755.1
NC_016593:3249767:3253889325388932558471959Geobacillus thermoleovorans CCB_US3_UF5 chromosome, completehypothetical protein8e-0755.1
NC_014915:3320768:3323701332370133256591959Geobacillus sp. Y412MC52 chromosome, complete genomehypothetical protein9e-0754.7
NC_013411:3314799:3317732331773233196901959Geobacillus sp. Y412MC61, complete genomehypothetical protein9e-0754.7
NC_015578:3309531:333112333311233331788666Treponema primitia ZAS-2 chromosome, complete genomesecreted protein7e-0651.6