Pre_GI: BLASTP Hits

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Query: NC_010516:583870:592570 Clostridium botulinum B1 str. Okra, complete genome

Start: 592570, End: 593421, Length: 852

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:564727:576142576142576993852Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein7e-160563
NC_009699:564455:575871575871576722852Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein7e-160563
NC_015520:224136:234285234285235133849Mahella australiensis 50-1 BON chromosome, complete genomehypothetical protein2e-57223
NC_009617:5545477:556648555664855567345861Clostridium beijerinckii NCIMB 8052 chromosome, complete genomehypothetical protein5e-57221
NC_020291:6055282:607079160707916071651861Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomehypothetical protein2e-46186
NC_013216:1219775:123584412358441236743900Desulfotomaculum acetoxidans DSM 771, complete genomeprotein of unknown function DUF1613e-45182
NC_014654:549966:553803553803554651849Halanaerobium sp. 'sapolanicus' chromosome, complete genomeProtein of unknown function DUF21794e-43174
NC_014152:2849991:287289028728902873735846Thermincola sp. JR, complete genomeProtein of unknown function DUF21795e-42171
NC_021171:1661923:166192316619231662807885Bacillus sp. 1NLA3E, complete genomehypothetical protein5e-36151
NC_013406:6568273:656891965689196569824906Paenibacillus sp. Y412MC10 chromosome, complete genomehypothetical protein5e-36151
NC_014624:3810163:383065438306543831526873Eubacterium limosum KIST612 chromosome, complete genomehypothetical protein3e-35148
NC_013216:4131563:415292841529284153800873Desulfotomaculum acetoxidans DSM 771, complete genomeprotein of unknown function DUF1611e-34147
NC_005945:1459357:146401914640191464900882Bacillus anthracis str. Sterne, complete genomehypothetical protein4e-34145
NC_007530:1459412:146406514640651464946882Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein4e-34145
NC_019978:2220863:222710322271032227957855Halobacteroides halobius DSM 5150, complete genomehypothetical protein1e-32140
NC_011661:1411383:141951914195191420355837Dictyoglomus turgidum DSM 6724, complete genomeprotein of unknown function DUF1619e-33140
NC_011297:1224749:123925412392541240090837Dictyoglomus thermophilum H-6-12, complete genomeYitT family protein7e-33140
NC_021182:3576815:359386935938693594810942Clostridium pasteurianum BC1, complete genomehypothetical protein3e-32139
NC_016751:1227495:123991912399191240809891Marinitoga piezophila KA3 chromosome, complete genomehypothetical protein3e-32139
NC_014829:3822125:384110238411023841998897Bacillus cellulosilyticus DSM 2522 chromosome, complete genomeProtein of unknown function DUF21799e-32137
NC_020410:3868573:387325838732583874136879Bacillus amyloliquefaciens subsp. plantarum UCMB5036 completeputative integral inner membrane protein4e-31135
NC_010718:2337209:235148723514872352371885Natranaerobius thermophilus JW/NM-WN-LF, complete genomeprotein of unknown function DUF1614e-31135
NC_019842:3921424:392602239260223926900879Bacillus amyloliquefaciens subsp. plantarum AS43.3 chromosome,hypothetical protein1e-30133
NC_009725:3878862:388273638827363883614879Bacillus amyloliquefaciens FZB42, complete genomeYdeO1e-30133
NC_014483:4772856:479072047907204791619900Paenibacillus polymyxa E681 chromosome, complete genomehypothetical protein2e-30132
NC_016630:1610723:162338316233831624249867Filifactor alocis ATCC 35896 chromosome, complete genomeYitT family protein1e-29130
NC_012673:785718:807341807341808228888Exiguobacterium sp. AT1b, complete genomeprotein of unknown function DUF1612e-29129
NC_006270:568171:584057584057584929873Bacillus licheniformis ATCC 14580, complete genomehypothetical protein1e-28127
NC_006322:567987:583847583847584719873Bacillus licheniformis ATCC 14580, complete genomeYdeO1e-28127
NC_015690:1186545:119187211918721192756885Paenibacillus mucilaginosus KNP414 chromosome, complete genomehypothetical protein6e-29127
NC_016935:1752001:175732817573281758212885Paenibacillus mucilaginosus 3016 chromosome, complete genomehypothetical protein6e-29127
NC_017192:1841987:185935618593561860198843Arcobacter sp. L, complete genomehypothetical protein2e-28126
UCMB5137:1:322853228533157873Bacillus atrophaeus UCMB-5137YdeO2e-28126
NC_021175:2037219:203629720362972037232936Streptococcus oligofermentans AS 1.3089, complete genomehypothetical protein5e-28124
NC_012914:6583000:658311065831106584009900Paenibacillus sp. JDR-2, complete genomeprotein of unknown function DUF1615e-28124
NC_017195:517344:557444557444558316873Bacillus subtilis subsp. subtilis str. RO-NN-1 chromosome, completeYdeO2e-27123
NC_016047:683368:688341688341689213873Bacillus subtilis subsp. spizizenii TU-B-10 chromosome, completehypothetical protein2e-27122
NC_011725:1182000:118545011854501186307858Bacillus cereus B4264 chromosome, complete genomehypothetical protein3e-26119
NC_011978:493800:509949509949510800852Thermotoga neapolitana DSM 4359, complete genomehypothetical protein3e-26119
NC_016641:2476634:248243324824332483269837Paenibacillus terrae HPL-003 chromosome, complete genomehypothetical protein3e-26119
NC_016630:1610723:161377116137711614661891Filifactor alocis ATCC 35896 chromosome, complete genomemembrane protein3e-26119
NC_020272:20435:371953719538073879Bacillus amyloliquefaciens IT-45, complete genomehypothetical protein1e-25116
NC_020291:1149887:114988711498871150729843Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomehypothetical protein2e-25116
NC_014844:762794:765425765425766303879Desulfovibrio aespoeensis Aspo-2 chromosome, complete genomehypothetical protein5e-25115
NC_017191:3901914:390642239064223907300879Bacillus amyloliquefaciens XH7 chromosome, complete genomeintegral inner membrane protein8e-25114
NC_017188:3900951:390473039047303905608879Bacillus amyloliquefaciens TA208 chromosome, complete genomeintegral inner membrane protein8e-25114
NC_019896:577594:598020598020598868849Bacillus subtilis subsp. subtilis str. BSP1 chromosome, completehypothetical protein9e-25114
NC_011134:1951682:195257919525791953526948Streptococcus equi subsp. zooepidemicus str. MGCS10565, completeintegral membrane protein1e-24114
NC_020410:3326944:335306133530613353909849Bacillus amyloliquefaciens subsp. plantarum UCMB5036 completeputative integral inner membrane protein6e-24111
NC_009718:1470972:148800814880081488865858Fervidobacterium nodosum Rt17-B1, complete genomehypothetical protein1e-23110
NC_007350:1629694:163277716327771633631855Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305,hypothetical protein2e-23109
NC_003228:1045207:104856810485681049458891Bacteroides fragilis NCTC 9343, complete genomeputative transmembrane protein3e-23109
NC_019960:1362370:137767813776781378592915Prevotella dentalis DSM 3688 chromosome 1, complete sequencehypothetical protein3e-23108
NC_011134:1951682:195168219516821952563882Streptococcus equi subsp. zooepidemicus str. MGCS10565, completehypothetical membrane protein1e-22107
NC_014363:114239:172239172239173153915Olsenella uli DSM 7084 chromosome, complete genomeProtein of unknown function DUF21792e-22106
NC_015391:1013608:103196610319661032862897Carnobacterium sp. 17-4 chromosome, complete genomeputative integral inner membrane protein6e-22104
NC_013198:1538792:157356915735691574489921Lactobacillus rhamnosus GG, complete genomeintegral membrane protein7e-22104
NC_020207:1795993:180403418040341804804771Enterococcus faecium NRRL B-2354, complete genomehypothetical protein1e-21103
NC_015160:2521849:253356225335622534449888Odoribacter splanchnicus DSM 20712 chromosome, complete genomehypothetical protein1e-21103
NC_009615:3581619:360064136006413601519879Parabacteroides distasonis ATCC 8503 chromosome, complete genometransporter3e-21102
NC_020207:1614000:161730616173061618238933Enterococcus faecium NRRL B-2354, complete genomehypothetical protein2e-20100
NC_012778:207415:207415207415208293879Eubacterium eligens ATCC 27750, complete genomehypothetical protein6e-2098.2
NC_010610:535790:537219537219538064846Lactobacillus fermentum IFO 3956, complete genomehypothetical protein2e-1893.2
NC_015516:1518000:152203315220331522899867Melissococcus plutonius ATCC 35311, complete genomehypothetical protein3e-1892.4
NC_019960:1658657:171481817148181715771954Prevotella dentalis DSM 3688 chromosome 1, complete sequencehypothetical protein3e-1892.4
NC_009483:739010:748173748173749021849Geobacter uraniireducens Rf4 chromosome, complete genomehypothetical protein5e-1788.6
NC_015164:2626503:265143126514312652327897Bacteroides salanitronis DSM 18170 chromosome, complete genomehypothetical protein1e-1687.4
NC_004193:2692136:270476027047602705653894Oceanobacillus iheyensis HTE831, complete genomehypothetical protein3e-1685.9
NC_019970:510632:514553514553515398846Thermoanaerobacterium thermosaccharolyticum M0795, complete genomehypothetical protein3e-1582.8
NC_014410:525645:530127530127530972846Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,1e-1480.5
NC_013421:4006085:401150640115064012120615Pectobacterium wasabiae WPP163, complete genomeprotein of unknown function DUF1612e-1376.3
NC_008528:1265542:127126312712631272129867Oenococcus oeni PSU-1, complete genomehypothetical protein4e-1272
NC_009952:1680682:169968616996861700312627Dinoroseobacter shibae DFL 12, complete genomehypothetical protein3e-1065.9
NC_007519:2773000:279703527970352797931897Desulfovibrio alaskensis G20 chromosome, complete genomehypothetical protein2e-0860.1
NC_015555:430054:4300544300544325162463Thermoanaerobacterium xylanolyticum LX-11 chromosome, complete8e-0754.7