Pre_GI: BLASTP Hits

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Query: NC_010516:583870:591193 Clostridium botulinum B1 str. Okra, complete genome

Start: 591193, End: 591741, Length: 549

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:564727:574765574765575313549Clostridium botulinum F str. 230613 chromosome, complete genomeNUDIX family hydrolase1e-98358
NC_009699:564455:574494574494575042549Clostridium botulinum F str. Langeland chromosome, complete genomeNUDIX family hydrolase1e-98358
NC_014328:3482980:350569435056943506242549Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative hydrolase4e-50197
NC_015732:982774:986982986982987548567Spirochaeta caldaria DSM 7334 chromosome, complete genomeNUDIX hydrolase3e-0858.2
NC_013406:3329791:333549933354993336008510Paenibacillus sp. Y412MC10 chromosome, complete genomeNUDIX hydrolase6e-0857
NC_007576:1564739:157122515712251571861637Lactobacillus sakei subsp. sakei 23K, complete genomePutative nucleotide diphosphate hydrolase, NUDIX family3e-0755.1
NC_014933:3942156:396801439680143968568555Bacteroides helcogenes P 36-108 chromosome, complete genomeNUDIX hydrolase1e-0653.1
NC_011894:5056901:507672850767285077270543Methylobacterium nodulans ORS 2060, complete genomeNUDIX hydrolase1e-0653.1
NC_011661:1049767:106594210659421066496555Dictyoglomus turgidum DSM 6724, complete genomeNUDIX hydrolase1e-0652.4
NC_014758:1992683:199620219962021996750549Calditerrivibrio nitroreducens DSM 19672 chromosome, completenudix hydrolase2e-0652
NC_015385:2505977:253945725394572540047591Treponema succinifaciens DSM 2489 chromosome, complete genomeNUDIX hydrolase3e-0651.6
NC_011027:858565:858002858002858568567Chlorobaculum parvum NCIB 8327, complete genomeNUDIX hydrolase4e-0650.8
NC_007759:623116:637747637747638301555Syntrophus aciditrophicus SB, complete genomephosphohydrolase5e-0650.4