Pre_GI: BLASTP Hits

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Query: NC_010516:583870:585332 Clostridium botulinum B1 str. Okra, complete genome

Start: 585332, End: 585814, Length: 483

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012658:545840:561475561475561936462Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein2e-34144
NC_017297:564727:568898568898569380483Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein3e-84310
NC_009699:564455:568626568626569108483Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein3e-84310