Pre_GI: BLASTP Hits

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Query: NC_010516:583870:584396 Clostridium botulinum B1 str. Okra, complete genome

Start: 584396, End: 584986, Length: 591

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012658:545840:560539560539561129591Clostridium botulinum Ba4 str. 657 chromosome, complete genomeputative methlytransferase6e-98356
NC_017297:564727:567962567962568552591Clostridium botulinum F str. 230613 chromosome, complete genomemethyltransferase-like protein1e-97355
NC_009699:564455:567690567690568280591Clostridium botulinum F str. Langeland chromosome, complete genomemethlytransferase-like protein1e-97355
NC_018870:354164:366781366781367380600Thermacetogenium phaeum DSM 12270 chromosome, complete genomemenaquinone biosynthesis methyltransferase UbiE1e-29129
NC_010644:254725:267625267625268212588Elusimicrobium minutum Pei191, complete genomemethyltransferase type 119e-1580.1
NC_009437:166179:181173181173181646474Caldicellulosiruptor saccharolyticus DSM 8903, complete genomemethyltransferase type 111e-1376.3
NC_014973:4630132:4662732466273246639071176Geobacter sp. M18 chromosome, complete genomeCyclopropane-fatty-acyl-phospholipid synthase1e-0653.1