Pre_GI: BLASTP Hits

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Query: NC_010516:514000:525978 Clostridium botulinum B1 str. Okra, complete genome

Start: 525978, End: 526841, Length: 864

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:490922:505958505958506821864Clostridium botulinum F str. 230613 chromosome, complete genomemetallo-beta-lactamase family protein2e-125449
NC_009699:490652:505688505688506551864Clostridium botulinum F str. Langeland chromosome, complete genomemetallo-beta-lactamase family protein2e-125449
NC_009495:482500:494523494523495386864Clostridium botulinum A str. ATCC 3502 chromosome, complete genomemetallo beta-lactamase superfamily lipoprotein2e-125448
NC_010520:496500:508756508756509619864Clostridium botulinum A3 str. Loch Maree, complete genomemetallo-beta-lactamase family protein2e-125448
NC_012563:519037:533717533717534580864Clostridium botulinum A2 str. Kyoto, complete genomemetallo-beta-lactamase family protein1e-124445
NC_009698:467500:479686479686480549864Clostridium botulinum A str. Hall chromosome, complete genomemetallo-beta-lactamase2e-124445
NC_009697:444801:459298459298460161864Clostridium botulinum A str. ATCC 19397 chromosome, completemetallo-beta-lactamase family protein2e-124445
NC_012658:482313:496519496519497382864Clostridium botulinum Ba4 str. 657 chromosome, complete genomemetallo-beta-lactamase family protein2e-122438
NC_011837:950000:975137975137976012876Clostridium kluyveri NBRC 12016, complete genomehypothetical protein3e-75281
NC_014328:711842:724612724612725472861Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative ComE-like protein1e-68259
NC_015425:2024154:202906720290672029936870Clostridium botulinum BKT015925 chromosome, complete genomecomE-like protein, metallo beta-lactamase superfamily hydrolase1e-62240
NC_021182:3409199:341020734102073411133927Clostridium pasteurianum BC1, complete genomeputative hydrolase (metallo-beta-lactamase superfamily)8e-62237
NC_019970:1991944:199194419919441992897954Thermoanaerobacterium thermosaccharolyticum M0795, complete genomeputative hydrolase (metallo-beta-lactamase superfamily)7e-61234
NC_008593:2020473:2040892204089220422081317Clostridium novyi NT, complete genomeMetallo-beta-lactamase superfamily protein1e-59229
NC_015425:2277570:2294149229414922953271179Clostridium botulinum BKT015925 chromosome, complete genomemetallo-beta-lactamase superfamily protein4e-59228
NC_015555:863173:879509879509880426918Thermoanaerobacterium xylanolyticum LX-11 chromosome, completebeta-lactamase domain protein4e-59228
NC_015573:893862:9200839200839212731191Desulfotomaculum kuznetsovii DSM 6115 chromosome, complete genomehypothetical protein1e-57223
NC_007644:1293701:1297449129744912984951047Moorella thermoacetica ATCC 39073, complete genomeBeta-lactamase-like2e-57222
NC_015425:1295261:1327851132785113291431293Clostridium botulinum BKT015925 chromosome, complete genomemetallo beta-lactamase superfamily hydrolase6e-55214
NC_018870:2316499:2317535231753523185451011Thermacetogenium phaeum DSM 12270 chromosome, complete genomebeta-lactamase-like protein9e-54210
NC_004557:558500:570458570458571333876Clostridium tetani E88, complete genomecomE operon protein5e-48191
NC_018876:2189798:219092721909272191892966Methanolobus psychrophilus R15 chromosome, complete genomecompetence-like protein3e-47189
NC_009633:3055413:309597330959733096854882Alkaliphilus metalliredigens QYMF chromosome, complete genomebeta-lactamase domain-containing protein2e-46186
NC_014721:2135500:2151860215186021529211062Caldicellulosiruptor kristjanssonii 177R1B chromosome, completehypothetical protein7e-45181
NC_014393:3425694:343246234324623433316855Clostridium cellulovorans 743B chromosome, complete genomeComE operon protein9e-44177
NC_003901:3698164:3698164369816436995791416Methanosarcina mazei Go1, complete genomecompetence-like protein2e-43176
NC_019977:2307000:2308144230814423094961353Methanomethylovorans hollandica DSM 15978, complete genomeputative hydrolase (metallo-beta-lactamase superfamily)8e-42171
NC_015873:2294312:230892823089282309860933Megasphaera elsdenii DSM 20460, complete genomemetallo-beta-lactamase family protein6e-40164
NC_020389:1730376:1737540173754017391111572Methanosarcina mazei Tuc01, complete genomehypothetical protein9e-33140
NC_017098:1542284:1565132156513215661661035Spirochaeta africana DSM 8902 chromosome, complete genomeputative hydrolase9e-33140
NC_015711:8852850:8852850885285088540461197Myxococcus fulvus HW-1 chromosome, complete genomemetallo-beta-lactamase family protein7e-33140
NC_011959:1965158:198185419818541982735882Thermomicrobium roseum DSM 5159, complete genomeComE operon protein 33e-32139
NC_012029:1865518:1872857187285718742901434Halorubrum lacusprofundi ATCC 49239 chromosome 1, complete genomebeta-lactamase domain protein6e-30131
NC_002608:268000:2835292835292849681440Halobacterium sp. NRC-1 plasmid pNRC200, complete sequenceComA1e-29130
NC_011772:4255161:4275374427537442776952322Bacillus cereus G9842, complete genomeDNA internalization-related competence protein ComEC/Rec27e-27121
NC_004722:4244730:4264966426496642672872322Bacillus cereus ATCC 14579, complete genomeComE operon protein 32e-26120
NC_011725:4288309:4308540430854043108612322Bacillus cereus B4264 chromosome, complete genomeDNA internalization-related competence protein ComEC/Rec22e-26119
NC_017208:4294341:4314574431457443168952322Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeComE operon protein 32e-26119
NC_015711:8852850:8854043885404388553711329Myxococcus fulvus HW-1 chromosome, complete genomemetallo-beta-lactamase family protein4e-26118
NC_010718:1229355:1242334124233412445862253Natranaerobius thermophilus JW/NM-WN-LF, complete genomeDNA internalization-related competence protein ComEC/Rec25e-25115
NC_015519:1113095:1131445113144511337902346Tepidanaerobacter sp. Re1 chromosome, complete genomeDNA internalization-related competence protein ComEC/Rec21e-24114
NC_014220:1732254:1732254173225417346382385Syntrophothermus lipocalidus DSM 12680 chromosome, complete genomeDNA internalization-related competence protein ComEC/Rec25e-23108
NC_017098:840492:842582842582843433852Spirochaeta africana DSM 8902 chromosome, complete genomeputative hydrolase5e-23108
NC_014328:3682000:369688736968873697711825Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative hydrolase1e-22107
NC_010424:697187:750359750359751183825Candidatus Desulforudis audaxviator MP104C, complete genomehypothetical protein2e-20100
NC_014972:2659388:2662774266277426653262553Desulfobulbus propionicus DSM 2032 chromosome, complete genomeDNA internalization-like competence protein ComEC/Rec23e-1995.9
NC_014833:2988814:300242730024273003290864Ruminococcus albus 7 chromosome, complete genomemetallo-beta-lactamase superfamily exported protein1e-1790.1
NC_015733:1680500:1700973170097317031052133Pseudomonas putida S16 chromosome, complete genomeacetyltransferase2e-1686.7
NC_014221:591785:6059306059306083202391Truepera radiovictrix DSM 17093 chromosome, complete genomeDNA internalization-related competence protein ComEC/Rec21e-1583.6
NC_014958:843456:8584288584288606592232Deinococcus maricopensis DSM 21211 chromosome, complete genomeDNA internalization-like competence protein ComEC/Rec22e-1479.7
NC_014394:1815638:1836295183629518386552361Gallionella capsiferriformans ES-2 chromosome, complete genomeDNA internalization-related competence protein ComEC/Rec21e-1377
NC_011186:515214:5323295323295344642136Vibrio fischeri MJ11 chromosome II, complete sequenceDNA internalization-related competence protein ComEC/Rec22e-1273.2
NC_007633:952728:9576229576229596882067Mycoplasma capricolum subsp. capricolum ATCC 27343, completemetallo-beta-lactamase superfamily protein, putative4e-0858.5
NC_008700:1627401:1627401162740116296982298Shewanella amazonensis SB2B, complete genomeDNA internalization-related competence protein ComEC/Rec29e-0857.8
NC_014751:946155:9510829510829529111830Mycoplasma leachii PG50 chromosome, complete genomemetallo-beta-lactamase family protein2e-0756.6
NC_014652:420457:4619444619444630031060Caldicellulosiruptor hydrothermalis 108 chromosome, complete1e-0654.3
NC_010617:1467000:1470227147022714729682742Kocuria rhizophila DC2201, complete genomeputative ComEC/Rec2-related protein1e-0653.9
NC_009454:2502724:250272425027242503689966Pelotomaculum thermopropionicum SI, complete genomehydrolase3e-0652.8