Pre_GI: BLASTP Hits

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Query: NC_010516:514000:525525 Clostridium botulinum B1 str. Okra, complete genome

Start: 525525, End: 525601, Length: 77

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010520:3837378:38465863846586384666277Clostridium botulinum A3 str. Loch Maree, complete genometRNA-Asn2e-0651.2
NC_010516:3807780:38169893816989381706577Clostridium botulinum B1 str. Okra, complete genometRNA-Asn2e-0651.2
NC_010516:3807780:38170913817091381716777Clostridium botulinum B1 str. Okra, complete genometRNA-Asn2e-0651.2
NC_012563:4004709:40139174013917401399377Clostridium botulinum A2 str. Kyoto, complete genometRNA-Asn2e-0651.2
NC_012563:519037:53318853318853326477Clostridium botulinum A2 str. Kyoto, complete genometRNA-Asn2e-0651.2
NC_010520:496500:50822050822050829677Clostridium botulinum A3 str. Loch Maree, complete genometRNA-Asn2e-0651.2