Pre_GI: BLASTP Hits

Some Help

Query: NC_010516:42475:68539 Clostridium botulinum B1 str. Okra, complete genome

Start: 68539, End: 68712, Length: 174

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009495:38000:686556865568936282Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein9e-25112
NC_012563:36000:627146271462995282Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein4e-24109
NC_017297:33519:637926379263965174Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein1e-23108
NC_010520:35845:626836268363105423Clostridium botulinum A3 str. Loch Maree, complete genomehypothetical protein5e-0959.7