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Query: NC_010516:359310:361098 Clostridium botulinum B1 str. Okra, complete genome

Start: 361098, End: 361652, Length: 555

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_019970:35985:431054310543611507Thermoanaerobacterium thermosaccharolyticum M0795, complete genomehypothetical protein1e-43175
NC_013446:2961647:298356029835602984117558Comamonas testosteroni CNB-2, complete genomehypothetical protein1e-31135
NC_010172:480000:490384490384490974591Methylobacterium extorquens PA1, complete genomeprotein of unknown function DUF10034e-31134
NC_012988:4292815:429885042988504299455606Methylobacterium extorquens DM4, complete genomehypothetical protein1e-26119
NC_012791:4736084:475043947504394750987549Variovorax paradoxus S110 chromosome 1, complete genomeprotein of unknown function DUF10032e-26118
NC_002939:3043068:304460130446013045077477Geobacter sulfurreducens PCA, complete genomehypothetical protein1e-25115
NC_017167:2203159:221570722157072216363657Alicyclobacillus acidocaldarius subsp. acidocaldarius Tc-4-1hypothetical protein2e-24111
NC_018000:1207231:121930412193041219657354Sinorhizobium fredii USDA 257 chromosome, complete genomehypothetical protein6e-22103
NC_016512:679688:701749701749702264516Propionibacterium acnes TypeIA2 P.acn17 chromosome, completehypothetical protein1e-1582.4
NC_009921:7249249:726683672668367267726891Frankia sp. EAN1pec, complete genomeprotein of unknown function DUF10031e-1272.4
NC_020126:4622371:463142846314284632309882Myxococcus stipitatus DSM 14675, complete genomeCrp/Fnr family transcriptional regulator2e-1271.6
NC_021066:1393750:139861413986141399114501Raoultella ornithinolytica B6, complete genomehypothetical protein3e-1271.2
NC_019673:895418:894919894919895425507Saccharothrix espanaensis DSM 44229 complete genomehypothetical protein4e-1167.8
NC_012660:5242392:526663652666365267154519Pseudomonas fluorescens SBW25 chromosome, complete genomehypothetical protein9e-0960.1