Pre_GI: BLASTP Hits

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Query: NC_010516:3466000:3469991 Clostridium botulinum B1 str. Okra, complete genome

Start: 3469991, End: 3471088, Length: 1098

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009698:3275839:3274761327476132758581098Clostridium botulinum A str. Hall chromosome, complete genomeR-2-hydroxyglutaryl-CoA dehydratase subunit0684
NC_021182:4088000:4109618410961841107091092Clostridium pasteurianum BC1, complete genomehypothetical protein1e-117422
NC_015425:2528549:2565637256563725667131077Clostridium botulinum BKT015925 chromosome, complete genomehypothetical protein3e-117422
NC_014377:1227850:1230332123033212314411110Thermosediminibacter oceani DSM 16646 chromosome, complete genomehypothetical protein3e-64245
NC_016584:1436710:1458512145851214596181107Desulfosporosinus orientis DSM 765 chromosome, complete genomehypothetical protein5e-47188
NC_011830:633195:6381006381006391941095Desulfitobacterium hafniense DCB-2, complete genomehypothetical protein8e-46184
NC_015425:2528549:256670625667062567560855Clostridium botulinum BKT015925 chromosome, complete genomehypothetical protein2e-0757.4
NC_014377:1227850:1231413123141312324231011Thermosediminibacter oceani DSM 16646 chromosome, complete genomeProtein of unknown function DUF2229, CoA enzyme activase3e-0756.6
NC_010516:3466000:346909534690953469988894Clostridium botulinum B1 str. Okra, complete genomehypothetical protein7e-0755.1
NC_013410:3192836:3192836319283631972874452Fibrobacter succinogenes subsp. succinogenes S85 chromosome,CoA-substrate-specific enzyme activase8e-0755.1
NC_021182:4088000:411070941107094111602894Clostridium pasteurianum BC1, complete genomehypothetical protein3e-0653.5