Pre_GI: BLASTP Hits

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Query: NC_010516:2900057:2906880 Clostridium botulinum B1 str. Okra, complete genome

Start: 2906880, End: 2907179, Length: 300

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:2905138:291155829115582911857300Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein3e-30130
NC_009699:2901497:291142029114202911719300Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein3e-30130
NC_010520:2937981:294723829472382947537300Clostridium botulinum A3 str. Loch Maree, complete genomehypothetical protein3e-30130
NC_012563:3090954:310188831018883102187300Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein6e-30129
NC_009495:2876865:288779928877992888098300Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein6e-30129
NC_009697:2790277:280121128012112801510300Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein6e-30129
NC_009698:2727203:273813727381372738436300Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein6e-30129
NC_012658:2930244:293939529393952939694300Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein3e-29126
NC_014328:1046958:106532910653291065631303Clostridium ljungdahlii ATCC 49587 chromosome, complete genomehypothetical protein2e-0651.2
NC_021182:2921000:293140329314032931693291Clostridium pasteurianum BC1, complete genomehypothetical protein2e-0651.2
NC_017295:2286911:230000023000002300266267Clostridium acetobutylicum EA 2018 chromosome, complete genomehypothetical protein1e-0548.9