Pre_GI: BLASTP Hits

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Query: NC_010516:2777205:2789072 Clostridium botulinum B1 str. Okra, complete genome

Start: 2789072, End: 2789995, Length: 924

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:2796000:280499928049992805922924Clostridium botulinum F str. 230613 chromosome, complete genomeHPr(Ser) kinase/phosphatase3e-170597
NC_010520:2807429:281960928196092820532924Clostridium botulinum A3 str. Loch Maree, complete genomeHPr(Ser) kinase/phosphatase5e-168590
NC_015425:906969:926829926829927752924Clostridium botulinum BKT015925 chromosome, complete genomeHPr kinase2e-114412
NC_008593:841291:863163863163864086924Clostridium novyi NT, complete genomeHPr kinase/phosphorylase8e-114410
NC_011999:530930:543423543423544352930Macrococcus caseolyticus JCSC5402, complete genomeHPr kinase/phosphatase4e-79295
NC_004722:5057825:506157950615795062508930Bacillus cereus ATCC 14579, complete genomeHPr kinase/phosphorylase2e-76286
NC_011658:4904156:491150049115004912429930Bacillus cereus AH187 chromosome, complete genomeHPr kinase/phosphorylase2e-76286
NC_011725:5075285:507903950790395079968930Bacillus cereus B4264 chromosome, complete genomeHPr kinase/phosphorylase2e-76286
NC_011969:4841358:484614148461414847070930Bacillus cereus Q1 chromosome, complete genomehpr kinase/phosphorylase2e-76286
NC_014171:4959248:496300249630024963931930Bacillus thuringiensis BMB171 chromosome, complete genomeHPr kinase/phosphorylase2e-76286
NC_016771:4859040:486382348638234864752930Bacillus cereus NC7401, complete genomeHPr(Ser) kinase/phosphatase2e-76286
NC_017200:4995075:499985849998585000787930Bacillus thuringiensis serovar finitimus YBT-020 chromosome,HPr kinase/phosphorylase2e-76286
NC_011772:5021404:502717050271705028099930Bacillus cereus G9842, complete genomeHPr(Ser) kinase/phosphatase3e-76285
NC_017208:5124333:513009951300995131028930Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeHPr kinase/phosphorylase3e-76285
NC_003909:4854379:4859162485916248602201059Bacillus cereus ATCC 10987, complete genomeHPr kinase/phosphorylase6e-76284
NC_011773:4940921:494466349446634945592930Bacillus cereus AH820 chromosome, complete genomeHPr kinase/phosphorylase5e-76284
NC_010184:4909183:491653549165354917464930Bacillus weihenstephanensis KBAB4, complete genomeHPr kinase5e-76284
NC_005957:4883306:488808948880894889018930Bacillus thuringiensis serovar konkukian str. 97-27, completeHPr kinase/phosphorylase5e-76284
NC_006274:4940922:494466449446644945593930Bacillus cereus E33L, complete genomeHPr kinase/phosphorylase5e-76284
NC_005945:4877752:488350448835044884433930Bacillus anthracis str. Sterne, complete genomeHPr kinase/phosphorylase5e-76284
NC_007530:4877500:488229348822934883222930Bacillus anthracis str. 'Ames Ancestor', complete genomeHPr kinase/phosphorylase5e-76284
NC_003997:4876415:488216748821674883096930Bacillus anthracis str. Ames, complete genomeHPr kinase/phosphorylase5e-76284
NC_012472:4908245:491198749119874912916930Bacillus cereus 03BB102, complete genomeHPr(Ser) kinase/phosphatase5e-76284
NC_012581:4882525:488461648846164885545930Bacillus anthracis str. CDC 684 chromosome, complete genomeHPr kinase/phosphorylase5e-76284
NC_012659:4877410:488219348821934883122930Bacillus anthracis str. A0248, complete genomeHPr kinase/phosphorylase5e-76284
NC_012781:629761:637118637118638059942Eubacterium rectale ATCC 33656, complete genomeHPr kinase/phosphorylase1e-72273
NC_017338:793024:805507805507806439933Staphylococcus aureus subsp. aureus JKD6159 chromosome, completeHPr(Ser) kinase/phosphatase2e-71269
NC_017353:2129738:215373921537392154674936Staphylococcus lugdunensis N920143, complete genomeHPr kinase/phosphatase6e-71267
NC_016048:1930089:196517619651761966117942Oscillibacter valericigenes Sjm18-20, complete genomeHPr kinase/phosphorylase9e-71266
NC_013791:1033700:104941910494191050357939Bacillus pseudofirmus OF4 chromosome, complete genomeHPr kinase/phosphorylase1e-69263
NC_014829:3822125:382417138241713825109939Bacillus cellulosilyticus DSM 2522 chromosome, complete genomeHPr kinase3e-69262
NC_010001:404066:411257411257412186930Clostridium phytofermentans ISDg, complete genomeHPr kinase4e-69261
NC_014915:3207300:322567032256703226605936Geobacillus sp. Y412MC52 chromosome, complete genomeHPr kinase3e-68258
NC_013411:3201331:321970132197013220636936Geobacillus sp. Y412MC61, complete genomeHPr kinase3e-68258
NC_012034:390273:418184418184419119936Anaerocellum thermophilum DSM 6725, complete genomeHPr kinase6e-68257
NC_004193:2522000:253840325384032539335933Oceanobacillus iheyensis HTE831, complete genomeHPr kinase/phosphorylase9e-66250
NC_012778:2049694:206097320609732061926954Eubacterium eligens ATCC 27750, complete genomeHPr kinase/phosphorylase2e-65249
NC_016894:2931213:2954214295421429552391026Acetobacterium woodii DSM 1030 chromosome, complete genomeHPr kinase/phosphorylase HprK2e-62239
NC_014758:1489761:149282814928281493805978Calditerrivibrio nitroreducens DSM 19672 chromosome, completehpr(ser) kinase/phosphatase3e-62239
NC_015278:333219:333786333786334766981Aerococcus urinae ACS-120-V-Col10a chromosome, complete genomeHPr(Ser) kinase/phosphatase1e-59229
NC_013939:1023443:104396610439661044943978Deferribacter desulfuricans SSM1, complete genomeHPr kinase2e-55216
NC_010814:2275199:231231023123102313269960Geobacter lovleyi SZ, complete genomeHPr kinase3e-52205
NC_019908:1512622:153208415320841533034951Brachyspira pilosicoli P43/6/78 chromosome, complete genomeHpr kinase phosphatase1e-51203
NC_010794:2071858:209244220924422093437996Methylacidiphilum infernorum V4, complete genomeSerine kinase of the HPr protein, regulates carbohydrate metabolism4e-49195
NC_013016:656000:677687677687678649963Neisseria meningitidis alpha14 chromosome, complete genomeHPr kinase/phosphorylase5e-37155
NC_017518:828662:845106845106846068963Neisseria meningitidis NZ-05/33 chromosome, complete genomeputative HPr(Ser) kinase/phosphatase HprK5e-37155
NC_003112:744476:767589767589768551963Neisseria meningitidis MC58, complete genomeHPr kinase/phosphorylase2e-37155
NC_017516:1535904:153673915367391537701963Neisseria meningitidis H44/76 chromosome, complete genomeputative HPr(Ser) kinase/phosphatase HprK2e-37155
NC_015731:990000:992413992413993372960Nitrosomonas sp. Is79A3 chromosome, complete genomeHPr kinase7e-37154
NC_014760:101469:107902107902108864963Mycoplasma bovis PG45 chromosome, complete genomeHPr(Ser) kinase/phosphatase7e-33141
NC_014100:172452:193716193716194165450Caulobacter segnis ATCC 21756 chromosome, complete genomeHPr kinase2e-0860.5
NC_014375:217612:242527242527242964438Brevundimonas subvibrioides ATCC 15264 chromosome, complete genomeHPr kinase6e-0858.5