Pre_GI: BLASTP Hits

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Query: NC_010516:2777205:2788525 Clostridium botulinum B1 str. Okra, complete genome

Start: 2788525, End: 2789079, Length: 555

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:2796000:280445228044522805006555Clostridium botulinum F str. 230613 chromosome, complete genome5-formyltetrahydrofolate cyclo-ligase3e-83306
NC_010520:2807429:281906228190622819616555Clostridium botulinum A3 str. Loch Maree, complete genome5-formyltetrahydrofolate cyclo-ligase family protein7e-82302
NC_008593:841291:864070864070864621552Clostridium novyi NT, complete genome5-formyltetrahydrofolate cyclo-ligase family protein8e-35146
NC_015425:906969:927736927736928284549Clostridium botulinum BKT015925 chromosome, complete genome5-formyltetrahydrofolate cyclo-ligase1e-33142
NC_014633:713285:728505728505729080576Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence5-formyltetrahydrofolate cyclo-ligase4e-25114
NC_013171:1336000:134453813445381345071534Anaerococcus prevotii DSM 20548, complete genome5-formyltetrahydrofolate cyclo-ligase3e-1375.1
NC_020304:1222000:122434812243481224929582Desulfocapsa sulfexigens DSM 10523, complete genome5,10-methenyltetrahydrofolate synthetase5e-1374.3
NC_015160:2521849:252184925218492522382534Odoribacter splanchnicus DSM 20712 chromosome, complete genome5-formyltetrahydrofolate cyclo-ligase8e-1373.2
NC_013939:441921:461727461727462269543Deferribacter desulfuricans SSM1, complete genome5-formyltetrahydrofolate cyclo-ligase3e-1271.6
NC_014972:3771642:377730737773073777915609Desulfobulbus propionicus DSM 2032 chromosome, complete genome5-formyltetrahydrofolate cyclo-ligase5e-1270.5
NC_014820:71565:911349113491655522Cenarchaeum symbiosum A, complete genome5-formyltetrahydrofolate cyclo-ligase3e-1168.2
NC_013406:5954472:597551159755115976158648Paenibacillus sp. Y412MC10 chromosome, complete genome5-formyltetrahydrofolate cyclo-ligase2e-1065.9
NC_014758:310394:340190340190340729540Calditerrivibrio nitroreducens DSM 19672 chromosome, complete5-formyltetrahydrofolate cyclo-ligase8e-0960.1
NC_008321:3964414:398466139846613985335675Shewanella sp. MR-4, complete genome5-formyltetrahydrofolate cyclo-ligase3e-0858.2
NC_014246:536338:558892558892559539648Mobiluncus curtisii ATCC 43063 chromosome, complete genome5-formyltetrahydrofolate cyclo-ligase5e-0857.4
NC_006512:2211654:223761622376162238203588Idiomarina loihiensis L2TR, complete genome5-formyltetrahydrofolate cyclo-ligase family protein5e-0857.4
NC_010162:9727465:973004997300499730654606Sorangium cellulosum 'So ce 56', complete genomeputative 5-formyltetrahydrofolate cyclo-ligase2e-0755.5
NC_013421:553193:578901578901579542642Pectobacterium wasabiae WPP163, complete genome5-formyltetrahydrofolate cyclo-ligase1e-0652.8
NC_013204:74855:9934099340100260921Eggerthella lenta DSM 2243, complete genome5-formyltetrahydrofolate cyclo-ligase6e-0650.4