Pre_GI: BLASTP Hits

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Query: NC_010516:2511035:2539103 Clostridium botulinum B1 str. Okra, complete genome

Start: 2539103, End: 2539375, Length: 273

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009698:2367171:239524823952482395520273Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein7e-44175
NC_009697:2394826:242290324229032423175273Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein7e-44175
NC_009495:2524000:255088025508802551152273Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein7e-44175
NC_010520:2585014:261363326136332613905273Clostridium botulinum A3 str. Loch Maree, complete genomehypothetical protein7e-44175
NC_012563:2721658:272539127253912725663273Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein7e-44175
NC_012658:2584355:260907626090762609348273Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein6e-43172
NC_020291:1464500:146989214698921470158267Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomehypothetical protein1e-33141
NC_014328:1405484:141178814117881412057270Clostridium ljungdahlii ATCC 49587 chromosome, complete genomehypothetical protein6e-31132
NC_008262:1835613:185364918536491853915267Clostridium perfringens SM101, complete genomehypothetical protein1e-30131
NC_016627:2799453:282000728200072820282276Clostridium clariflavum DSM 19732 chromosome, complete genomeputative nucleic-acid-binding protein implicated in transcription termination5e-28122
NC_011898:513835:522592522592522864273Clostridium cellulolyticum H10, complete genomeprotein of unknown function DUF4483e-26117
NC_007907:2879568:288605828860582886327270Desulfitobacterium hafniense Y51, complete genomehypothetical protein7e-25112
NC_011830:3904034:391334539133453913614270Desulfitobacterium hafniense DCB-2, complete genomeprotein of unknown function DUF4487e-25112
NC_019970:1343670:135379613537961354065270Thermoanaerobacterium thermosaccharolyticum M0795, complete genomeputative nucleic-acid-binding protein implicated in transcription termination1e-23108
NC_010001:3369500:338101233810123381287276Clostridium phytofermentans ISDg, complete genomeprotein of unknown function DUF4484e-22103
NC_015589:1899329:191626919162691916535267Desulfotomaculum ruminis DSM 2154 chromosome, complete genomehypothetical protein8e-22102
NC_014376:3214222:322490332249033225172270Clostridium saccharolyticum WM1 chromosome, complete genomeprotein of unknown function DUF4481e-21101
NC_009253:2139379:215023821502382150504267Desulfotomaculum reducens MI-1 chromosome, complete genomehypothetical protein1e-21101
NC_014152:1430156:144175814417581442054297Thermincola sp. JR, complete genomeprotein of unknown function DUF4482e-21101
NC_013216:3376186:339012533901253390394270Desulfotomaculum acetoxidans DSM 771, complete genomeprotein of unknown function DUF4482e-21100
NC_020134:1173000:117843311784331178717285Clostridium stercorarium subsp. stercorarium DSM 8532, completehypothetical protein4e-2096.7
NC_014103:3985897:399790539979053998186282Bacillus megaterium DSM319 chromosome, complete genomehypothetical protein1e-1892
NC_014387:1175927:118575911857591186016258Butyrivibrio proteoclasticus B316 chromosome 1, complete genomehypothetical protein1e-1891.7
NC_009674:2551759:256191625619162562197282Bacillus cytotoxicus NVH 391-98 chromosome, complete genomehypothetical protein3e-1890.5
NC_013315:1370000:137824513782451378526282Clostridium difficile CD196 chromosome, complete genomehypothetical protein7e-1889.4
NC_017208:3816753:382724838272483827520273Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeputative cytoplasmic protein7e-1889.4
NC_004722:3777907:378800737880073788288282Bacillus cereus ATCC 14579, complete genomehypothetical Cytosolic Protein9e-1889
NC_011772:3787500:379761437976143797886273Bacillus cereus G9842, complete genomehypothetical protein9e-1889
NC_017179:1378875:138802513880251388300276Clostridium difficile BI1, complete genomehypothetical protein8e-1889
NC_011969:3549000:355918535591853559457273Bacillus cereus Q1 chromosome, complete genomehypothetical protein1e-1788.6
NC_011773:3651963:366206536620653662337273Bacillus cereus AH820 chromosome, complete genomehypothetical protein1e-1788.6
NC_011658:3603009:361522336152233615495273Bacillus cereus AH187 chromosome, complete genomehypothetical protein1e-1788.6
NC_014335:3567931:357803135780313578303273Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein1e-1788.6
NC_012472:3661912:367201236720123672284273Bacillus cereus 03BB102, complete genomehypothetical protein1e-1788.6
NC_007530:3616828:362730636273063627578273Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein1e-1788.6
NC_003997:3617000:362717936271793627451273Bacillus anthracis str. Ames, complete genomehypothetical protein1e-1788.6
NC_003909:3587695:359991035999103600182273Bacillus cereus ATCC 10987, complete genomehypothetical protein1e-1788.6
NC_012659:3617000:362720636272063627478273Bacillus anthracis str. A0248, complete genomehypothetical protein1e-1788.6
NC_016771:3555506:356772035677203567992273Bacillus cereus NC7401, complete genomehypothetical protein1e-1788.6
NC_008600:3643905:365400536540053654286282Bacillus thuringiensis str. Al Hakam, complete genomehypothetical protein1e-1788.6
NC_006274:3697255:370773237077323708013282Bacillus cereus E33L, complete genomehypothetical protein1e-1788.6
NC_005945:3615623:362787436278743628155282Bacillus anthracis str. Sterne, complete genomehypothetical protein1e-1788.6
NC_005957:3638750:364885036488503649131282Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein1e-1788.6
NC_014171:3701051:371115237111523711424273Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein1e-1788.6
NC_011725:3821789:383189238318923832164273Bacillus cereus B4264 chromosome, complete genomehypothetical protein1e-1788.6
NC_017200:3655496:366890936689093669181273Bacillus thuringiensis serovar finitimus YBT-020 chromosome,hypothetical protein1e-1788.6
NC_016779:3579743:358984335898433590115273Bacillus cereus F837/76 chromosome, complete genomehypothetical protein1e-1788.6
NC_010184:3675424:368593736859373686209273Bacillus weihenstephanensis KBAB4, complete genomeprotein of unknown function DUF4485e-1786.3
NC_014657:944000:955570955570955854285Caldicellulosiruptor owensensis OL chromosome, complete genomehypothetical protein2e-1580.9
NC_017341:1291583:130213413021341302418285Staphylococcus aureus subsp. aureus str. JKD6008 chromosome,hypothetical protein1e-1478.6
NC_017338:1234077:124232812423281242612285Staphylococcus aureus subsp. aureus JKD6159 chromosome, completehypothetical protein1e-1478.6
NC_007622:1214629:122518012251801225464285Staphylococcus aureus RF122, complete genomehypothetical protein1e-1478.6
NC_002952:1291444:130199513019951302279285Staphylococcus aureus subsp. aureus MRSA252, complete genomehypothetical protein1e-1478.6
NC_009782:1327340:133789113378911338175285Staphylococcus aureus subsp. aureus Mu3, complete genomehypothetical protein1e-1478.6
NC_012121:897866:908499908499908783285Staphylococcus carnosus subsp. carnosus TM300, complete genomehypothetical protein3e-1477.4
NC_004461:921364:948628948628948912285Staphylococcus epidermidis ATCC 12228, complete genomehypothetical protein3e-1477
NC_014727:1292213:131393313139331314232300Lactobacillus delbrueckii subsp. bulgaricus ND02 chromosome,nucleic-acid-binding protein implicated in transcription termination2e-1374.3
NC_017353:1699652:170925817092581709551294Staphylococcus lugdunensis N920143, complete genomehypothetical protein4e-1373.6
NC_021175:1597613:162081216208121621108297Streptococcus oligofermentans AS 1.3089, complete genomehypothetical protein1e-1271.6
NC_009009:1876367:189453318945331894829297Streptococcus sanguinis SK36, complete genomehypothetical protein4e-1270.1
NC_007350:1551457:155622215562221556506285Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305,hypothetical protein8e-1269.3
NC_009004:1770497:177367817736781774004327Lactococcus lactis subsp. cremoris MG1363, complete genomeconserved hypothetical protein2e-1167.8
NC_008527:740060:758073758073758399327Lactococcus lactis subsp. cremoris SK11, complete genomePredicted nucleic-acid-binding protein implicated in transcription termination2e-1167.8
NC_007297:1379742:138291813829181383214297Streptococcus pyogenes MGAS5005, complete genomehypothetical cytosolic protein5e-1063.2
NC_008023:1398085:140126114012611401560300Streptococcus pyogenes MGAS2096, complete genomehypothetical cytosolic protein5e-1063.2
NC_008021:1374195:137737113773711377670300Streptococcus pyogenes MGAS9429, complete genomehypothetical cytosolic protein5e-1063.2
NC_013939:1535071:154744415474441548028585Deferribacter desulfuricans SSM1, complete genomehypothetical protein1e-0962
NC_017294:758992:778469778469778738270Candidatus Arthromitus sp. SFB-mouse-Yit, complete genomehypothetical protein2e-0961.2
NC_019435:747162:765198765198765503306Lactococcus lactis subsp. cremoris UC509.9, complete genomehypothetical protein5e-0856.6
NC_013170:917177:921471921471921788318Cryptobacterium curtum DSM 15641, complete genomepredicted nucleic-acid-binding protein implicated in transcription termination6e-0856.2
NC_005042:1480761:150632015063201506598279Prochlorococcus marinus subsp. marinus str. CCMP1375, completePredicted nucleic-acid-binding protein implicated in transcription termination3e-0650.4