Pre_GI: BLASTP Hits

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Query: NC_010516:2511035:2519073 Clostridium botulinum B1 str. Okra, complete genome

Start: 2519073, End: 2520614, Length: 1542

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010520:2585014:2593605259360525951461542Clostridium botulinum A3 str. Loch Maree, complete genomeHDIG/HD/KH domain protein0743
NC_012563:2680246:2705363270536327069041542Clostridium botulinum A2 str. Kyoto, complete genomeHDIG/HD/KH domain protein0743
NC_009698:2367171:2375219237521923767601542Clostridium botulinum A str. Hall chromosome, complete genomephosphodiesterase0742
NC_009697:2394826:2402874240287424044151542Clostridium botulinum A str. ATCC 19397 chromosome, completephosphodiesterase0742
NC_009495:2524000:2530851253085125323921542Clostridium botulinum A str. ATCC 3502 chromosome, complete genomephosphodiesterase0742
NC_009699:2576500:2579588257958825811291542Clostridium botulinum F str. Langeland chromosome, complete genomephosphodiesterase0741
NC_017297:2575306:2579728257972825812691542Clostridium botulinum F str. 230613 chromosome, complete genomeHDIG/HD/KH domain protein0741
NC_012658:2584355:2589323258932325908641542Clostridium botulinum Ba4 str. 657 chromosome, complete genomephosphodiesterase0739
NC_008262:1835613:1835613183561318371481536Clostridium perfringens SM101, complete genomeHD superfamily hydrolase, YMDA8e-166583
NC_008261:2157713:2161565216156521631001536Clostridium perfringens ATCC 13124, complete genomeHDIG/KH domain protein9e-166583
NC_014652:1758787:1767669176766917692341566Caldicellulosiruptor hydrothermalis 108 chromosome, completemetal dependent phosphohydrolase2e-143509
NC_014721:1028841:1040246104024610418111566Caldicellulosiruptor kristjanssonii 177R1B chromosome, completemetal dependent phosphohydrolase3e-143509
NC_010184:3590895:3605305360530536068701566Bacillus weihenstephanensis KBAB4, complete genomeRNA binding metal dependent phosphohydrolase4e-140498
NC_011772:3705878:3716980371698037185451566Bacillus cereus G9842, complete genomeHDIG/HD/KH domain protein9e-140497
NC_014171:3661512:3672613367261336741751563Bacillus thuringiensis BMB171 chromosome, complete genomephosphodiesterase1e-139497
NC_011725:3785769:3793350379335037949121563Bacillus cereus B4264 chromosome, complete genomephosphodiesterase1e-139497
NC_011773:3615998:3623145362314536247071563Bacillus cereus AH820 chromosome, complete genomephosphodiesterase1e-139496
NC_017200:3622838:3629982362998236315441563Bacillus thuringiensis serovar finitimus YBT-020 chromosome,phosphodiesterase2e-139496
NC_016771:3520522:3528769352876935303341566Bacillus cereus NC7401, complete genomeHDIG/HD/KH domain-containing protein3e-139495
NC_006274:3661194:3668776366877636703381563Bacillus cereus E33L, complete genomehypothetical protein7e-139494
NC_014335:3531931:3539072353907235406341563Bacillus cereus biovar anthracis str. CI chromosome, completemetal dependent phosphohydrolase7e-139494
NC_003997:3579972:3588223358822335897851563Bacillus anthracis str. Ames, complete genomehypothetical protein7e-139494
NC_007530:3581202:3588350358835035899121563Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein7e-139494
NC_012472:3625800:3633382363338236349441563Bacillus cereus 03BB102, complete genomeHDIG/HD/KH domain protein7e-139494
NC_005945:3581776:3588924358892435904861563Bacillus anthracis str. Sterne, complete genomehypothetical protein7e-139494
NC_005957:3602744:3609892360989236114541563Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein7e-139494
NC_012581:639329:6487766487766503381563Bacillus anthracis str. CDC 684 chromosome, complete genomephosphodiesterase7e-139494
NC_012659:3579999:3588250358825035898121563Bacillus anthracis str. A0248, complete genomephosphodiesterase7e-139494
NC_008600:3611038:3615375361537536170001626Bacillus thuringiensis str. Al Hakam, complete genomepossible hydrolase4e-139494
NC_008346:1431051:1445059144505914466061548Syntrophomonas wolfei subsp. wolfei str. Goettingen, completeHDIG/KH domain protein6e-136484
NC_015391:695350:7019637019637035221560Carnobacterium sp. 17-4 chromosome, complete genomephosphodiesterase1e-135483
NC_015499:119200:1620781620781636251548Thermodesulfobium narugense DSM 14796 chromosome, complete genome2,3 cyclic-nucleotide 2-phosphodiesterase2e-130466
NC_009943:677324:6773246773246788861563Candidatus Desulfococcus oleovorans Hxd3, complete genomeRNA binding metal dependent phosphohydrolase5e-127455
NC_008554:3177723:3190710319071031922721563Syntrophobacter fumaroxidans MPOB, complete genomemetal dependent phosphohydrolase3e-126452
NC_013939:441921:4622694622694638281560Deferribacter desulfuricans SSM1, complete genomehypothetical protein8e-125447
NC_011768:4571869:4589606458960645911801575Desulfatibacillum alkenivorans AK-01, complete genomeRNA binding metal dependent phosphohydrolase1e-123443
NC_018645:2301705:2309552230955223111171566Desulfobacula toluolica Tol2, complete genome2',3'-cyclic-nucleotide 2'-phosphodiesterase7e-121434
NC_007759:723675:7338797338797354441566Syntrophus aciditrophicus SB, complete genomehydrolase2e-120433
NC_014758:310394:3407333407333422951563Calditerrivibrio nitroreducens DSM 19672 chromosome, completemetal dependent phosphohydrolase1e-119430
NC_014960:1735786:1798168179816817997061539Anaerolinea thermophila UNI-1, complete genomehypothetical protein8e-119427
NC_014972:3227500:3232267323226732338321566Desulfobulbus propionicus DSM 2032 chromosome, complete genomemetal dependent phosphohydrolase3e-117422
NC_012108:3965433:3975256397525639768181563Desulfobacterium autotrophicum HRM2, complete genomeKH domain/HD domain family protein4e-117422
NC_011296:1299388:1303371130337113049301560Thermodesulfovibrio yellowstonii DSM 11347, complete genomehydrolase, HAD superfamily5e-113408
NC_011883:2031222:2044016204401620455751560Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774,RNA binding metal dependent phosphohydrolase5e-113408
NC_015577:3735558:3741991374199137435201530Treponema azotonutricium ZAS-9 chromosome, complete genomehypothetical protein2e-111403
NC_015434:1671532:1675809167580916775751767Verrucosispora maris AB-18-032 chromosome, complete genomemetal dependent phosphohydrolase1e-110400
NC_015318:1455444:1459843145984314614051563Hippea maritima DSM 10411 chromosome, complete genome2,3 cyclic-nucleotide 2-phosphodiesterase1e-109397
NC_015732:3105649:3119620311962031211431524Spirochaeta caldaria DSM 7334 chromosome, complete genome2,3 cyclic-nucleotide 2-phosphodiesterase9e-109394
NC_005303:272915:3140473140473156331587Onion yellows phytoplasma OY-M, complete genomehypothetical protein7e-103374
NC_011653:1463743:1475789147578914773211533Thermosipho africanus TCF52B, complete genomehypothetical protein2e-101370
NC_004663:5817782:5820481582048158220161536Bacteroides thetaiotaomicron VPI-5482, complete genomehypothetical protein3e-99362
NC_015496:2436089:2450814245081424523791566Krokinobacter diaphorus 4H-3-7-5 chromosome, complete genomemetal dependent phosphohydrolase6e-97355
NC_012526:4462:90179017107141698Deinococcus deserti VCD115, complete genomehypothetical protein3e-93342
NC_009802:1077926:1090608109060810921251518Campylobacter concisus 13826, complete genomehypothetical protein9e-92337
NC_017192:1137724:1158899115889911604431545Arcobacter sp. L, complete genomephosphodiesterase5e-86318