Pre_GI: BLASTP Hits

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Query: NC_010516:2511035:2514284 Clostridium botulinum B1 str. Okra, complete genome

Start: 2514284, End: 2514541, Length: 258

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009698:2367171:237043023704302370687258Clostridium botulinum A str. Hall chromosome, complete genomephosphocarrier protein HPr3e-40163
NC_009697:2394826:239808523980852398342258Clostridium botulinum A str. ATCC 19397 chromosome, completephosphocarrier protein HPr3e-40163
NC_009495:2524000:252606225260622526319258Clostridium botulinum A str. ATCC 3502 chromosome, complete genomephosphocarrier protein HPr3e-40163
NC_012563:2680246:270057427005742700831258Clostridium botulinum A2 str. Kyoto, complete genomephosphocarrier protein HPr3e-40163
NC_010520:2585014:258827325882732588530258Clostridium botulinum A3 str. Loch Maree, complete genomephosphocarrier protein HPr3e-40163
NC_008261:2157713:215938621593862159646261Clostridium perfringens ATCC 13124, complete genomephosphocarrier, HPr family2e-29127
NC_015697:321311:341107341107341373267Lactobacillus reuteri SD2112 chromosome, complete genomePTS family porter component HPr4e-1890.1
NC_009513:1363987:138094213809421381208267Lactobacillus reuteri F275, complete genomePhosphotransferase system, phosphocarrier protein HPr4e-1890.1
NC_008497:1498430:151444615144461514712267Lactobacillus brevis ATCC 367, complete genomePhosphotransferase system, HPr-related protein8e-1682.4
NC_008525:664500:664974664974665240267Pediococcus pentosaceus ATCC 25745, complete genomePhosphotransferase system, HPr-related protein1e-1581.3
NC_007644:3229:150311503115312282Moorella thermoacetica ATCC 39073, complete genomeHPrNtr8e-1579
NC_016641:2291363:230946623094662309732267Paenibacillus terrae HPL-003 chromosome, complete genomephosphocarrier protein HPr1e-1479
NC_015978:996933:101769610176961017962267Lactobacillus sanfranciscensis TMW 1.1304 chromosome, completephosphocarrier protein HPr1e-1478.6
NC_013642:942767:972165972165972425261Thermotoga naphthophila RKU-10, complete genomePhosphotransferase system, phosphocarrier protein HPr3e-1477
NC_010483:642577:647832647832648092261Thermotoga sp. RQ2, complete genomePhosphotransferase system, phosphocarrier protein HPr6e-1476.3
NC_006510:1014500:101630610163061016572267Geobacillus kaustophilus HTA426, complete genomephosphocarrier protein (histidine-containing protein)7e-1475.9
NC_020210:901240:903371903371903637267Geobacillus sp. GHH01, complete genomephosphocarrier protein HPr7e-1475.9
NC_014829:3772914:377407637740763774333258Bacillus cellulosilyticus DSM 2522 chromosome, complete genomePhosphotransferase system, phosphocarrier protein HPr7e-1475.9
NC_007712:2897000:290911029091102909367258Sodalis glossinidius str. 'morsitans', complete genomePTS system phosphocarrier protein HPr7e-1475.9
NC_004193:2522000:252201325220132522273261Oceanobacillus iheyensis HTE831, complete genomecatabolite repression HPr-like protein8e-1475.9
NC_013716:2476334:249619324961932496450258Citrobacter rodentium ICC168, complete genomephosphocarrier protein HPr1e-1375.5
NC_009012:3224000:322672932267293226998270Clostridium thermocellum ATCC 27405, complete genomeHPrNtr domain containing protein9e-1475.5
NC_016593:1092812:109489510948951095203309Geobacillus thermoleovorans CCB_US3_UF5 chromosome, completehypothetical protein8e-1475.5
NC_009708:1522281:154341515434151543672258Yersinia pseudotuberculosis IP 31758 chromosome, complete genomePTS system phosphohistidinoprotein-hexose phosphotransferase Hpr1e-1375.1
NC_004545:15650:693256932569582258Buchnera aphidicola str. Bp (Baizongia pistaciae), complete genomephosphocarrier protein HPr2e-1374.3
NC_015565:2827444:284259328425932842862270Desulfotomaculum carboxydivorans CO-1-SRB chromosome, completephosphotransferase system, phosphocarrier protein HPr4e-1373.6
NC_010001:404066:416274416274416531258Clostridium phytofermentans ISDg, complete genomePhosphotransferase system, phosphocarrier protein HPr4e-1373.6
NC_016605:1177485:119919911991991199465267Pediococcus claussenii ATCC BAA-344 chromosome, complete genomephosphocarrier protein HPr4e-1373.2
NC_010794:2071858:209212420921242092441318Methylacidiphilum infernorum V4, complete genomePhosphotransferase system HPr-related protein2e-1271.2
NC_013517:1849912:186357818635781863838261Sebaldella termitidis ATCC 33386, complete genomePhosphotransferase system, phosphocarrier protein HPr3e-1270.9
NC_009437:2579161:258085625808562581116261Caldicellulosiruptor saccharolyticus DSM 8903, complete genomephosphotransferase system, phosphocarrier protein HPr4e-1270.1
NC_014654:1802007:180703118070311807309279Halanaerobium sp. 'sapolanicus' chromosome, complete genomePhosphotransferase system, phosphocarrier protein HPr8e-1268.9
NC_013416:875758:891618891618891875258Aggregatibacter actinomycetemcomitans D11S-1, complete genomephosphocarrier protein HPr3e-1167
NC_016513:1185241:120109912010991201356258Aggregatibacter actinomycetemcomitans ANH9381 chromosome, completephosphocarrier protein HPr3e-1167
NC_014483:195321:213074213074213343270Paenibacillus polymyxa E681 chromosome, complete genomeHPr-like protein crh (Catabolite repression HPr)4e-1166.6
NC_016627:762000:779508779508779771264Clostridium clariflavum DSM 19732 chromosome, complete genomephosphotransferase system HPr (HPr) family protein6e-1166.2
NC_014976:2735423:276021427602142760489276Bacillus subtilis BSn5 chromosome, complete genomephosphocarrier protein HPr1e-1064.7
NC_014624:171394:176252176252176527276Eubacterium limosum KIST612 chromosome, complete genomehypothetical protein2e-1064.7
NC_012559:2854640:285819228581922858461270Laribacter hongkongensis HLHK9, complete genomePtsH2e-1064.7
NC_008639:2786447:281852228185222818833312Chlorobium phaeobacteroides DSM 266, complete genomePhosphotransferase system, phosphocarrier protein HPr2e-1064.3
NC_011060:244949:248225248225248491267Pelodictyon phaeoclathratiforme BU-1, complete genomePhosphotransferase system, phosphocarrier protein HPr4e-1063.5
NC_019949:525249:532358532358532621264Mycoplasma cynos C142 complete genomePhosphocarrier, HPr family4e-1063.5
NC_014721:314990:321936321936322286351Caldicellulosiruptor kristjanssonii 177R1B chromosome, completephosphotransferase system, phosphocarrier protein hpr5e-1063.2
NC_015949:2156843:217325721732572173595339Caldicellulosiruptor lactoaceticus 6A chromosome, complete genomephosphotransferase system, phosphocarrier protein HPr5e-1063.2
NC_009674:3732000:375146137514613751718258Bacillus cytotoxicus NVH 391-98 chromosome, complete genomephosphocarrier protein Chr8e-1062.4
NC_006155:1567306:1583090158309015842231134Yersinia pseudotuberculosis IP 32953, complete genomePTS system, fructose-specific II component / phosphocarrier p...1e-0962
NC_003143:1441211:1456994145699414581271134Yersinia pestis CO92, complete genomehypothetical protein1e-0962
NC_010159:1558000:1573109157310915742421134Yersinia pestis Angola, complete genomephosphocarrier, HPr family1e-0962
NC_008149:3022970:3025620302562030267531134Yersinia pestis Nepal516, complete genomehypothetical protein1e-0962
NC_010634:1565788:1581587158158715827201134Yersinia pseudotuberculosis PB1/+, complete genomeHPr family phosphocarrier protein1e-0962
NC_005810:1413305:1415955141595514170881134Yersinia pestis biovar Microtus str. 91001, complete genomebifunctional fructose-specific PTS IIA/HPr protein1e-0962
NC_009708:3035798:3038448303844830395811134Yersinia pseudotuberculosis IP 31758 chromosome, complete genomebifunctional PTS system fructose-specific transporter subunit IIA/HPr protein1e-0962
NC_008150:1147883:1163094116309411642271134Yersinia pestis Antiqua, complete genomehypothetical protein1e-0962
NC_004088:3186954:3189604318960431907371134Yersinia pestis KIM, complete genomePTS system, fructose-specific IIA/fpr component1e-0962
NC_010465:3046904:3049554304955430506871134Yersinia pseudotuberculosis YPIII, complete genomephosphocarrier, HPr family1e-0962
NC_017265:2807302:2809952280995228110851134Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,IIA and HPr components of fructose-specific PTS enzyme1e-0962
NC_017168:4363000:4379062437906243801951134Yersinia pestis A1122 chromosome, complete genomebifunctional PTS system fructose-specific transporter subunit IIA/HPr protein1e-0962
NC_017160:1299733:1302191130219113033241134Yersinia pestis D182038 chromosome, complete genomehypothetical protein1e-0962
NC_017154:1454704:1470488147048814716211134Yersinia pestis D106004 chromosome, complete genomehypothetical protein1e-0962
NC_014029:1512605:1528380152838015295131134Yersinia pestis Z176003 chromosome, complete genomehypothetical protein1e-0962
NC_009381:2731965:2734615273461527357481134Yersinia pestis Pestoides F chromosome, complete genomebifunctional PTS system fructose-specific transporter subunit IIA/HPr protein1e-0962
NC_011899:2165814:217334321733432173627285Halothermothrix orenii H 168, complete genomePhosphotransferase system, phosphocarrier protein HPr1e-0961.6
NC_011916:467106:4671064671064696642559Caulobacter crescentus NA1000 chromosome, complete genomephosphoenolpyruvate-protein phosphotransferase/phosphocarrier protein HPr/PTS system, glucose-specific IIA subunit3e-0960.5
NC_007530:4853740:487268348726834872931249Bacillus anthracis str. 'Ames Ancestor', complete genomephosphocarrier protein hpr4e-0960.1
NC_005945:4854951:487389448738944874142249Bacillus anthracis str. Sterne, complete genomephosphocarrier protein HPr4e-0960.1
NC_003997:4852332:487255748725574872805249Bacillus anthracis str. Ames, complete genomephosphocarrier protein HPr4e-0960.1
NC_003909:4831000:484954948495494849797249Bacillus cereus ATCC 10987, complete genomephosphocarrier protein HPr4e-0960.1
NC_008600:4868000:488575248857524886000249Bacillus thuringiensis str. Al Hakam, complete genomephosphocarrier protein HPr4e-0960.1
NC_011773:4914601:493505349350534935301249Bacillus cereus AH820 chromosome, complete genomephosphocarrier protein Chr4e-0960.1
NC_012581:4856620:487500648750064875254249Bacillus anthracis str. CDC 684 chromosome, complete genomephosphocarrier protein Chr4e-0960.1
NC_012659:4853640:487258348725834872831249Bacillus anthracis str. A0248, complete genomephosphocarrier protein Chr4e-0960.1
NC_014171:4933200:495337649533764953624249Bacillus thuringiensis BMB171 chromosome, complete genomephosphocarrier protein Chr4e-0960.1
NC_010814:2275199:231077023107702311036267Geobacter lovleyi SZ, complete genomePhosphotransferase system, phosphocarrier protein HPr5e-0959.7
NC_016047:637778:647431647431647706276Bacillus subtilis subsp. spizizenii TU-B-10 chromosome, completephosphocarrier protein HPr7e-0959.3
NC_017195:2498113:250478325047832505058276Bacillus subtilis subsp. subtilis str. RO-NN-1 chromosome, completephosphocarrier protein HPr7e-0959.3
NC_012032:1827244:183104218310421831314273Chloroflexus sp. Y-400-fl, complete genomePhosphotransferase system, phosphocarrier protein HPr9e-0958.9
NC_010175:1825878:182966418296641829948285Chloroflexus aurantiacus J-10-fl, complete genomephosphocarrier, HPr family9e-0958.9
NC_012856:207194:236274236274236543270Ralstonia pickettii 12D chromosome 1, complete genomePhosphotransferase system, phosphocarrier protein HPr2e-0858.2
NC_016513:317197:3400363400363415651530Aggregatibacter actinomycetemcomitans ANH9381 chromosome, completebifunctional PTS system fructose-specific transporter subunit IIA/HPr protein2e-0858.2
NC_014121:3553809:3554507355450735556371131Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completebifunctional fructose-specific PTS IIA/HPr protein1e-0858.2
NC_006905:3913988:391921839192183919487270Salmonella enterica subsp. enterica serovar Choleraesuis strputative phosphotransferase system, HPr-related protein4e-0856.6
NC_011083:3985618:399376039937603994029270Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,phosphotransferase system HPr enzyme4e-0856.6
NC_004631:3841975:385446638544663854735270Salmonella enterica subsp. enterica serovar Typhi Ty2, completeputative phosphocarrier protein of PTS system4e-0856.6
NC_003197:3971905:397955139795513979820270Salmonella typhimurium LT2, complete genomeputative phosphotransferase system HPr protein4e-0856.6
NC_003198:3855157:386897638689763869245270Salmonella enterica subsp. enterica serovar Typhi str. CT18,putative PTS system phosphocarrier protein4e-0856.6
NC_011094:3853036:386126238612623861531270Salmonella enterica subsp. enterica serovar Schwarzengrund strphosphotransferase system HPr enzyme4e-0856.6
NC_012125:3905782:391400839140083914277270Salmonella enterica subsp. enterica serovar Paratyphi C strainPTS system phosphocarrier protein4e-0856.6
NC_016810:3993863:400086440008644001133270Salmonella enterica subsp. enterica serovar Typhimurium strputative phosphocarrier protein of PTS system4e-0856.6
NC_016856:3985597:399324339932433993512270Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sputative phosphotransferase system HPr protein4e-0856.6
NC_016857:3993864:400086540008654001134270Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative PTS system phosphocarrier protein4e-0856.6
NC_016860:3995445:400244740024474002716270Salmonella enterica subsp. enterica serovar Typhimurium strputative PTS system phosphocarrier protein4e-0856.6
NC_016863:3933848:394085039408503941119270Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1putative phosphotransferase system HPr protein4e-0856.6
NC_017046:3991551:399969239996923999961270Salmonella enterica subsp. enterica serovar Typhimurium str. 798PTS system phosphocarrier protein4e-0856.6
NC_003454:249304:264311264311264580270Fusobacterium nucleatum subsp. nucleatum ATCC 25586, completePhosphocarrier protein HPr7e-0856.2
NC_011147:3755725:376336237633623763631270Salmonella enterica subsp. enterica serovar Paratyphi A strPTS system phosphocarrier protein7e-0855.8
NC_011080:3941909:395013539501353950404270Salmonella enterica subsp. enterica serovar Newport str. SL254,phosphotransferase system HPr enzyme7e-0855.8
NC_011149:3895921:390406339040633904332270Salmonella enterica subsp. enterica serovar Agona str. SL483,phosphotransferase system HPr enzyme7e-0855.8
NC_006511:3759550:376768337676833767952270Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCCputative PTS system phosphocarrier protein7e-0855.8
NC_009633:587562:594647594647594910264Alkaliphilus metalliredigens QYMF chromosome, complete genomephosphotransferase system, phosphocarrier protein HPr8e-0855.8
NC_010622:249625:305289305289305558270Burkholderia phymatum STM815 chromosome 1, complete sequencePhosphotransferase system, phosphocarrier protein HPr1e-0755.5
NC_012032:1827244:183622418362241836523300Chloroflexus sp. Y-400-fl, complete genomePhosphotransferase system, phosphocarrier protein HPr9e-0855.5
NC_010175:1825878:183485818348581835157300Chloroflexus aurantiacus J-10-fl, complete genomephosphocarrier, HPr family9e-0855.5
NC_010102:3919999:392764539276453927914270Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein1e-0755.1
NC_006177:1060428:107142410714241071681258Symbiobacterium thermophilum IAM 14863, complete genomePTS system phosphocarrier protein Hpr2e-0754.7
NC_014921:777047:799567799567799836270Mycoplasma fermentans M64 chromosome, complete genomephosphocarrier protein hpr3e-0753.9
NC_008344:554229:553970553970554239270Nitrosomonas eutropha C91, complete genomephosphocarrier, HPr family protein5e-0753.1
NC_012914:2360989:238234623823462382606261Paenibacillus sp. JDR-2, complete genomePhosphotransferase system, phosphocarrier protein HPr6e-0752.8
NC_018604:2350054:236394423639442364210267Brachyspira pilosicoli WesB complete genomephosphocarrier protein HPr2e-0650.8
NC_014330:888366:902163902163902429267Brachyspira pilosicoli 95/1000 chromosome, complete genomephosphocarrier protein HPr2e-0650.8
NC_018607:2231975:224589122458912246157267Brachyspira pilosicoli B2904 chromosome, complete genomephosphocarrier protein HPr2e-0650.8
NC_019908:2312194:231795623179562318222267Brachyspira pilosicoli P43/6/78 chromosome, complete genomephosphocarrier protein HPr2e-0650.8
NC_014100:172452:192957192957193226270Caulobacter segnis ATCC 21756 chromosome, complete genomePhosphotransferase system, phosphocarrier protein HPr1e-0548.9