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Query: NC_010516:2511035:2514035 Clostridium botulinum B1 str. Okra, complete genome

Start: 2514035, End: 2514256, Length: 222

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012563:2680246:270032527003252700546222Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein1e-33141
NC_009495:2524000:252580425258042526034231Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein2e-33140
NC_009698:2367171:237018123701812370402222Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein2e-33140
NC_009697:2394826:239783623978362398057222Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein2e-33140
NC_010520:2585014:258802425880242588245222Clostridium botulinum A3 str. Loch Maree, complete genomehypothetical protein3e-33140
NC_009495:482500:504799504799505014216Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein1e-0755.5
NC_009697:444801:469575469575469790216Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein1e-0755.5
NC_009698:467500:489963489963490178216Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein1e-0755.5
NC_012563:519037:544164544164544379216Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein2e-0754.3
NC_017297:490922:516220516220516435216Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein3e-0753.9
NC_009699:490652:515951515951516166216Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein3e-0753.9
NC_010718:497222:514926514926515120195Natranaerobius thermophilus JW/NM-WN-LF, complete genomeprotein of unknown function DUF3788e-0752.4
NC_014722:193500:203652203652204068417Burkholderia rhizoxinica HKI 454, complete genomehypothetical protein6e-0649.7
NC_009089:4140764:414663441466344146825192Clostridium difficile 630, complete genomehypothetical protein9e-0648.9
NC_013316:4018451:402504840250484025239192Clostridium difficile R20291, complete genomehypothetical protein9e-0648.9