Pre_GI: BLASTP Hits

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Query: NC_010516:2511035:2512367 Clostridium botulinum B1 str. Okra, complete genome

Start: 2512367, End: 2513797, Length: 1431

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009698:2367171:2368499236849923699291431Clostridium botulinum A str. Hall chromosome, complete genomeadenylosuccinate lyase0942
NC_009697:2394826:2396154239615423975841431Clostridium botulinum A str. ATCC 19397 chromosome, completeadenylosuccinate lyase0942
NC_009495:2524000:2524131252413125255611431Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeadenylosuccinate lyase0942
NC_012563:2680246:2698657269865727000871431Clostridium botulinum A2 str. Kyoto, complete genomeadenylosuccinate lyase0939
NC_010520:2585014:2586342258634225877721431Clostridium botulinum A3 str. Loch Maree, complete genomeadenylosuccinate lyase0932
NC_008261:2157713:2157713215771321591431431Clostridium perfringens ATCC 13124, complete genomeadenylosuccinate lyase0779
NC_015737:2691246:2706171270617127076041434Clostridium sp. SY8519, complete genomehypothetical protein0665
NC_014720:1737574:1737574173757417390041431Caldicellulosiruptor kronotskyensis 2002 chromosome, completeadenylosuccinate lyase0642
NC_003454:983681:9971289971289985611434Fusobacterium nucleatum subsp. nucleatum ATCC 25586, completeadenylosuccinate lyase8e-173607
NC_013515:347671:3905393905393919691431Streptobacillus moniliformis DSM 12112, complete genomeadenylosuccinate lyase2e-151535
NC_014960:1670778:1691849169184916932611413Anaerolinea thermophila UNI-1, complete genomeadenylosuccinate lyase1e-75284
NC_013595:4951396:4954840495484049562701431Streptosporangium roseum DSM 43021, complete genomeadenylosuccinate lyase ; K01756 adenylosuccinate lyase1e-57224
NC_016111:409852:4164234164234178561434Streptomyces cattleya NRRL 8057, complete genomeadenylosuccinate lyase9e-55214
NC_002677:2642860:2647523264752326489411419Mycobacterium leprae TN, complete genomeadenylosuccinate lyase9e-52204
NC_015690:8019859:8024113802411380254081296Paenibacillus mucilaginosus KNP414 chromosome, complete genomePurB9e-40165
NC_004193:783958:7886557886557899501296Oceanobacillus iheyensis HTE831, complete genomeadenylosuccinate lyase1e-39164
NC_000909:858840:8588408588408602281389Methanocaldococcus jannaschii DSM 2661, complete genomeadenylosuccinate lyase5e-39162
NC_017208:256163:3089703089703102771308Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeadenylosuccinate lyase7e-38158
NC_014171:261952:3193123193123206191308Bacillus thuringiensis BMB171 chromosome, complete genomeadenylosuccinate lyase7e-38158
NC_011567:238249:2536612536612549801320Anoxybacillus flavithermus WK1, complete genomeAdenylosuccinate lyase9e-38158
NC_009253:2577316:2594530259453025958221293Desulfotomaculum reducens MI-1 chromosome, complete genomeadenylosuccinate lyase1e-37157
NC_018704:433402:4372184372184385131296Amphibacillus xylanus NBRC 15112, complete genomeadenylosuccinate lyase5e-37155
NC_015574:114426:1158061158061171551350Methanobacterium sp. SWAN-1 chromosome, complete genomeadenylosuccinate lyase6e-37155
NC_016023:1725294:1739214173921417405091296Bacillus coagulans 36D1 chromosome, complete genomeadenylosuccinate lyase1e-36154
NC_011296:530408:5412415412415425331293Thermodesulfovibrio yellowstonii DSM 11347, complete genomeadenylosuccinate lyase4e-35149
NC_014829:443500:4489274489274502221296Bacillus cellulosilyticus DSM 2522 chromosome, complete genomeadenylosuccinate lyase2e-34147
NC_010556:462500:4760684760684773631296Exiguobacterium sibiricum 255-15, complete genomeadenylosuccinate lyase2e-34147
NC_018665:422451:4358274358274371221296Exiguobacterium antarcticum B7 chromosome, complete genomeAdenylosuccinate lyase2e-33144
NC_017347:2017097:2030691203069120319861296Staphylococcus aureus subsp. aureus T0131 chromosome, completeAdenylosuccinate lyase1e-33144
NC_010718:464405:4797994797994810911293Natranaerobius thermophilus JW/NM-WN-LF, complete genomeAdenylosuccinate lyase1e-33144
NC_015873:790961:8039288039288052201293Megasphaera elsdenii DSM 20460, complete genomeadenylosuccinate lyase1e-33144
NC_012673:2152639:2172426217242621737181293Exiguobacterium sp. AT1b, complete genomeadenylosuccinate lyase1e-33144
NC_008022:35983:5202952029533211293Streptococcus pyogenes MGAS10270, complete genomeAdenylosuccinate lyase4e-33142
NC_014314:576465:6264376264376277921356Dehalogenimonas lykanthroporepellens BL-DC-9 chromosome, completeadenylosuccinate lyase5e-33142
NC_008024:35948:5312653126544181293Streptococcus pyogenes MGAS10750, complete genomeAdenylosuccinate lyase6e-33142
NC_008021:35661:5164851648529401293Streptococcus pyogenes MGAS9429, complete genomeadenylosuccinate lyase1e-32141
NC_008023:35663:5162351623529151293Streptococcus pyogenes MGAS2096, complete genomeAdenylosuccinate lyase1e-32141
NC_007296:35661:5133151331526231293Streptococcus pyogenes MGAS6180, complete genomeadenylosuccinate lyase2e-32140
NC_002932:937157:9371579371579384611305Chlorobium tepidum TLS, complete genomeadenylosuccinate lyase2e-32140
NC_009483:2401209:2416176241617624174711296Geobacter uraniireducens Rf4 chromosome, complete genomeadenylosuccinate lyase6e-32139
NC_016148:1105669:1141361114136111426711311Thermovirga lienii DSM 17291 chromosome, complete genomeadenylosuccinate lyase5e-32139
NC_003485:35971:5193351933532251293Streptococcus pyogenes MGAS8232, complete genomeadenylosuccinate lyase5e-32139
NC_007517:2165657:2169723216972321710181296Geobacter metallireducens GS-15, complete genomeAdenylosuccinate lyase5e-32139
NC_011297:1224749:1256412125641212577131302Dictyoglomus thermophilum H-6-12, complete genomeadenylosuccinate lyase9e-32138
NC_009443:29349:4487044870461621293Streptococcus suis 98HAH33, complete genomeadenylosuccinate lyase2e-31137
NC_012924:29353:4487244872461641293Streptococcus suis SC84, complete genomeadenylosuccinate lyase2e-31137
NC_012926:30351:4487044870461621293Streptococcus suis BM407 chromosome, complete genomeadenylosuccinate lyase2e-31137
NC_012925:29353:4487244872461641293Streptococcus suis P1/7, complete genomeadenylosuccinate lyase2e-31137
NC_014498:99015:1116941116941129921299Streptococcus pneumoniae 670-6B chromosome, complete genomeadenylosuccinate lyase6e-31135
NC_010380:124655:1373341373341386321299Streptococcus pneumoniae Hungary19A-6, complete genomeadenylosuccinate lyase6e-31135
NC_016605:766836:7912417912417925451305Pediococcus claussenii ATCC BAA-344 chromosome, complete genomeadenylosuccinate lyase1e-30134
NC_009975:1565865:1582480158248015838291350Methanococcus maripaludis C6, complete genomeadenylosuccinate lyase2e-29130
NC_016024:1472421:1490880149088014922591380Candidatus Chloracidobacterium thermophilum B chromosome chromosomeadenylosuccinate lyase8e-29128
NC_016026:1760856:1777384177738417786881305Micavibrio aeruginosavorus ARL-13 chromosome, complete genomeadenylosuccinate lyase5e-26119
NC_009482:1652329:1652329165232916536241296Synechococcus sp. RCC307 chromosome, complete genomeadenylosuccinate lyase2e-25117
NC_014471:217279:2333842333842347301347Ignisphaera aggregans DSM 17230 chromosome, complete genomeAdenylosuccinate lyase8e-25115
NC_006833:637964:6549036549036561951293Wolbachia endosymbiont strain TRS of Brugia malayi, completeAdenylosuccinate lyase2e-24114
NC_010981:712843:7186997186997200001302Wolbachia pipientis, complete genomeadenylosuccinate lyase1e-24114
NC_000921:1147394:1151605115160511529271323Helicobacter pylori J99, complete genomeadenylosuccinate lyase7e-24112
NC_015499:119200:1319641319641332561293Thermodesulfobium narugense DSM 14796 chromosome, complete genomeadenylosuccinate lyase3e-23110
NC_007797:914500:9215309215309228281299Anaplasma phagocytophilum HZ, complete genomeadenylosuccinate lyase2e-21103
NC_014205:17445:2546725467268491383Staphylothermus hellenicus DSM 12710 chromosome, complete genomeadenylosuccinate lyase7e-2099
NC_009850:11076:2535625356266841329Arcobacter butzleri RM4018, complete genomeadenylosuccinate lyase3e-1997.1
NC_017187:10320:2478024780261081329Arcobacter butzleri ED-1, complete genomeadenylosuccinate lyase3e-1894
NC_014618:2139639:2147672214767221490361365Enterobacter cloacae SCF1 chromosome, complete genomeadenylosuccinate lyase9e-1788.6
NC_010002:1584500:1607626160762616090081383Delftia acidovorans SPH-1, complete genome3-carboxy-cis,cis-muconate cycloisomerase2e-1687.8
NC_015696:486250:5018075018075031051299Francisella sp. TX077308 chromosome, complete genomeadenylosuccinate lyase2e-1687.4
NC_008369:1780945:1780945178094517822431299Francisella tularensis subsp. holarctica OSU18, complete genomeadenylosuccinate lyase5e-1686.3
NC_009749:1776600:1777212177721217785101299Francisella tularensis subsp. holarctica FTA, complete genomeadenylosuccinate lyase5e-1686.3
NC_007880:1780702:1781314178131417826121299Francisella tularensis subsp. holarctica, complete genomeadenylosuccinate lyase5e-1686.3
NC_008601:1811327:1811327181132718126251299Francisella tularensis subsp. novicida U112, complete genomeadenylosuccinate lyase5e-1686.3
NC_012779:2064582:2073711207371120750751365Edwardsiella ictaluri 93-146, complete genomeadenylosuccinate lyase, putative7e-1685.9
NC_006582:2205154:2205969220596922073421374Bacillus clausii KSM-K16, complete genomeadenylosuccinate lyase2e-1584.3
NC_011295:779569:7960257960257973231299Coprothermobacter proteolyticus DSM 5265, complete genomeadenylosuccinate lyase4e-1583.2
NC_015723:430165:4318304318304330051176Cupriavidus necator N-1 chromosome 2, complete sequenceGntR family transcriptional regulator4e-1583.2
NC_016582:9551123:9564275956427595656211347Streptomyces bingchenggensis BCW-1 chromosome, complete genome3-carboxy-cis,cis-muconate cycloisomerase1e-1481.6
NC_008313:2629281:2638033263803326393791347Ralstonia eutropha H16 chromosome 1, complete sequence3-Carboxy-cis,cis-muconate cyclo-isomerase1e-0964.7
NC_010729:1344903:1360808136080813621511344Porphyromonas gingivalis ATCC 33277, complete genomeadenylosuccinate lyase2e-0861.2
NC_008697:118859:1435031435031448581356Nocardioides sp. JS614 plasmid pNOCA01, complete sequencefumarate lyase4e-0860.1
NC_007498:3085511:3100161310016131015161356Pelobacter carbinolicus DSM 2380, complete genomeadenylosuccinate lyase6e-0859.3
NC_005139:2201820:2266108226610822674871380Vibrio vulnificus YJ016 chromosome I, complete sequenceadenylosuccinate lyase2e-0757.8
NC_010338:4148667:4167187416718741683411155Caulobacter sp. K31, complete genome3-carboxy-cis,cis-muconate cycloisomerase3e-0756.6
NC_015577:786155:8064288064288078941467Treponema azotonutricium ZAS-9 chromosome, complete genomeputative adenylosuccinate lyase1e-0654.7