Pre_GI: BLASTP Hits

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Query: NC_010516:2511035:2511035 Clostridium botulinum B1 str. Okra, complete genome

Start: 2511035, End: 2512312, Length: 1278

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009698:2367171:2367171236717123684481278Clostridium botulinum A str. Hall chromosome, complete genometRNA uridine 5-carboxymethylaminomethyl modification protein GidA0771
NC_009697:2394826:2394826239482623961031278Clostridium botulinum A str. ATCC 19397 chromosome, completetRNA uridine 5-carboxymethylaminomethyl modification protein GidA0771
NC_010520:2585014:2585014258501425862911278Clostridium botulinum A3 str. Loch Maree, complete genometRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA0768
NC_012563:2680246:2697461269746126986061146Clostridium botulinum A2 str. Kyoto, complete genometRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA0751
NC_003366:2057656:2078639207863920799161278Clostridium perfringens str. 13, complete genomehypothetical protein9e-165580
NC_008262:1950205:1967389196738919686661278Clostridium perfringens SM101, complete genomeputative FAD dependent oxidoreductase1e-164579
NC_010674:2435241:2450718245071824519951278Clostridium botulinum B str. Eklund 17B, complete genomepyridine nucleotide-disulphide oxidoreductase family protein3e-160564
NC_010321:1177238:1190792119079211920751284Thermoanaerobacter pseudethanolicus ATCC 33223 chromosome, completeglucose-inhibited division protein A1e-142506
NC_014964:1169925:1182983118298311842661284Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completeglucose-inhibited division protein A1e-142506
NC_010320:1585974:1597261159726115985441284Thermoanaerobacter sp. X514 chromosome, complete genomeglucose-inhibited division protein A3e-142505
NC_014538:1311500:1315838131583813171211284Thermoanaerobacter sp. X513 chromosome, complete genomeglucose-inhibited division protein A3e-142505
NC_014033:1564733:1579585157958515808591275Prevotella ruminicola 23 chromosome, complete genomeputative glucose inhibited division protein A4e-135481
NC_014393:2771774:279963127996312800422792Clostridium cellulovorans 743B chromosome, complete genomeglucose-inhibited division protein A7e-98357