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Query: NC_010516:2328288:2339066 Clostridium botulinum B1 str. Okra, complete genome

Start: 2339066, End: 2340772, Length: 1707

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_007929:785875:7908777908777924571581Lactobacillus salivarius subsp. salivarius UCC118, complete genomePhage NTP-binding protein6e-130464
NC_014365:2037506:204396520439652044735771Desulfarculus baarsii DSM 2075 chromosome, complete genomehypothetical protein4e-1893.2
NC_012984:520000:523406523406524122717Lactobacillus plantarum JDM1, complete genomephage NTP-binding protein3e-1377.4
NC_004606:877707:886097886097886777681Streptococcus pyogenes SSI-1, complete genomehypothetical protein7e-0652.8
NC_008024:804157:809116809116809796681Streptococcus pyogenes MGAS10750, complete genomephage protein7e-0652.8
NC_008022:771767:777849777849778529681Streptococcus pyogenes MGAS10270, complete genomephage protein7e-0652.8