Pre_GI: BLASTN Hits

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Query: NC_010418:70000 Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete

Start: 70000, End: 92099, Length: 22100

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A3 str. Loch Maree was isolated from duck liver paste during a botulism outbreak at a hotel in the Scottish highlands in 1922. This was the first and worst outbreak of botulism in the United Kingdom (UK). This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_007322:112209922099Bacillus anthracis str. 'Ames Ancestor' plasmid pXO1, complete4e-0867.9BLASTN svgBLASTP svg
NC_014331:112209922099Bacillus cereus biovar anthracis str. CI plasmid pCI-XO1, complete4e-0867.9BLASTN svgBLASTP svg
NC_012563:3580000*3580000360253222533Clostridium botulinum A2 str. Kyoto, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_010418:13832513832516678028456Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete01146BLASTN svgBLASTP svg
NC_010379:73718737189609922382Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence3e-40174BLASTN svgBLASTP svg
NC_010379:11076011076013543724678Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence1e-0869.9BLASTN svgBLASTP svg
NC_010516:23282882328288235225123964Clostridium botulinum B1 str. Okra, complete genome1e-29139BLASTN svgBLASTP svg
NC_021182:4829000*4829000485931530316Clostridium pasteurianum BC1, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_013515:715009*71500975125536247Streptobacillus moniliformis DSM 12112, complete genome1e-0869.9BLASTN svgBLASTP svg