Some Help

Query: NC_010418:188138:194794 Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete

Start: 194794, End: 195498, Length: 705

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A3 str. Loch Maree was isolated from duck liver paste during a botulism outbreak at a hotel in the Scottish highlands in 1922. This was the first and worst outbreak of botulism in the United Kingdom (UK). This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010379:6880:289162891629581666Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequenceUpf86.81e-28126
NC_020054:2260500:228891922889192289602684Fibrella aestuarina BUZ 2 drat genomehypothetical protein8e-26117
NC_007907:2534462:254477425447742545394621Desulfitobacterium hafniense Y51, complete genomehypothetical protein7e-25114
NC_011770:2690501:269429326942932695231939Pseudomonas aeruginosa LESB58, complete genomehypothetical protein3e-23108
NC_002927:2338549:233789123378912338556666Bordetella bronchiseptica RB50, complete genomehypothetical protein3e-23108
NC_011770:1431740:143877414387741439643870Pseudomonas aeruginosa LESB58, complete genomehypothetical protein3e-23108
NC_013722:218847:220210220210220815606Xanthomonas albilineans, complete genomehypothetical protein5e-22104
NC_013132:4803460:481361648136164814266651Chitinophaga pinensis DSM 2588, complete genomehypothetical protein6e-21100
NC_014838:218000:227117227117227818702Pantoea sp. At-9b plasmid pPAT9B01, complete sequencehypothetical protein7e-2097.4
NC_015856:3170771:319121031912103191689480Collimonas fungivorans Ter331 chromosome, complete genomephage-like protein2e-1996.3
NC_011283:3177350:319481831948183195441624Klebsiella pneumoniae 342 chromosome, complete genomehypothetical protein7e-1890.9
NC_014562:1883517:188871018887101889387678Pantoea vagans C9-1 chromosome, complete genomehypothetical protein8e-1890.5
NC_013850:2182337:218649421864942187204711Klebsiella variicola At-22 chromosome, complete genomeputative morphogenetic protein3e-1789
NC_011894:3671162:369212136921213692840720Methylobacterium nodulans ORS 2060, complete genomehypothetical protein5e-1787.8
NC_014839:253961:304245304245304844600Pantoea sp. At-9b plasmid pPAT9B02, complete sequencephage-like protein7e-1787.4
NC_014364:2693840:269682926968292697434606Spirochaeta smaragdinae DSM 11293 chromosome, complete genomehypothetical protein9e-1787
NC_014306:3006028:301209930120993012761663Erwinia billingiae Eb661, complete genomehypothetical protein4e-1685.1
NC_011894:3029964:303203930320393032674636Methylobacterium nodulans ORS 2060, complete genomehypothetical protein7e-1580.9
NC_014364:2111685:213155221315522132241690Spirochaeta smaragdinae DSM 11293 chromosome, complete genomehypothetical protein2e-1375.9
NC_010655:2065567:207976520797652080487723Akkermansia muciniphila ATCC BAA-835, complete genomeconserved hypothetical phage related protein2e-0962.8
NC_007005:2191500:220521122052112205459249Pseudomonas syringae pv. syringae B728a, complete genome2e-0755.8