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Query: NC_010161:2548254 Bartonella tribocorum CIP 105476, complete genome

Start: 2548254, End: 2576099, Length: 27846

Host Lineage: Bartonella tribocorum; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This organism was isolated from the blood of wild rats and from fleas obtained from wild rats. Transmission of these organisms is often through an insect vector. Once in a host, this intracellular pathogen is internalized by an actin-dependent mechanism, and primarily targets endothelial cells, although other cells can be infected. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells. This organism is genetically related to Bartonella elizabethae which was isolated from a case of endocarditis in a human.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_010161:19496371949637198084231206Bartonella tribocorum CIP 105476, complete genome026480BLASTN svgBLASTP svg
NC_010161:1501758*1501758153237830621Bartonella tribocorum CIP 105476, complete genome024400BLASTN svgBLASTP svg
NC_010161:13243811324381135291528535Bartonella tribocorum CIP 105476, complete genome024400BLASTN svgBLASTP svg
NC_020301:85326785326787983926573Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genome02843BLASTN svgBLASTP svg
NC_020301:669000*66900071117642177Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genome01160BLASTN svgBLASTP svg
NC_008783:29972*299725377323802Bartonella bacilliformis KC583, complete genome5e-79303BLASTN svgBLASTP svg
NC_010161:1179000*1179000119858119582Bartonella tribocorum CIP 105476, complete genome9e-50206BLASTN svgBLASTP svg
NC_005955:173436*17343619910325668Bartonella quintana str. Toulouse, complete genome2e-38168BLASTN svgBLASTP svg
NC_012846:986877986877102533738461Bartonella grahamii as4aup, complete genome1e-36163BLASTN svgBLASTP svg
NC_012846:92957092957095327323704Bartonella grahamii as4aup, complete genome5e-36161BLASTN svgBLASTP svg
NC_005956:1455496*1455496147609920604Bartonella henselae str. Houston-1, complete genome5e-36161BLASTN svgBLASTP svg
NC_010161:596034*59603462009924066Bartonella tribocorum CIP 105476, complete genome2e-32149BLASTN svgBLASTP svg
NC_005956:1019788*1019788103773717950Bartonella henselae str. Houston-1, complete genome3e-28135BLASTN svgBLASTP svg
NC_005956:818000*81800084009922100Bartonella henselae str. Houston-1, complete genome1e-24123BLASTN svgBLASTP svg
NC_010161:23811952381195240409922905Bartonella tribocorum CIP 105476, complete genome6e-1177.8BLASTN svgBLASTP svg
NC_010161:1914000*1914000193826824269Bartonella tribocorum CIP 105476, complete genome2e-0765.9BLASTN svgBLASTP svg