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Query: NC_010161:205500 Bartonella tribocorum CIP 105476, complete genome

Start: 205500, End: 232099, Length: 26600

Host Lineage: Bartonella tribocorum; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This organism was isolated from the blood of wild rats and from fleas obtained from wild rats. Transmission of these organisms is often through an insect vector. Once in a host, this intracellular pathogen is internalized by an actin-dependent mechanism, and primarily targets endothelial cells, although other cells can be infected. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells. This organism is genetically related to Bartonella elizabethae which was isolated from a case of endocarditis in a human.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_005955:173436*17343619910325668Bartonella quintana str. Toulouse, complete genome03239BLASTN svgBLASTP svg
NC_020301:174467*17446720609931633Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genome03092BLASTN svgBLASTP svg
NC_005956:19697619697622268225707Bartonella henselae str. Houston-1, complete genome02866BLASTN svgBLASTP svg
NC_012846:17088401708840173059921760Bartonella grahamii as4aup, complete genome0839BLASTN svgBLASTP svg
NC_014932:1232346*1232346130968277337Bartonella clarridgeiae 73, complete genome0791BLASTN svgBLASTP svg
NC_012846:19936519936524748348119Bartonella grahamii as4aup, complete genome3e-108400BLASTN svgBLASTP svg
NC_010161:1844452*1844452186659922148Bartonella tribocorum CIP 105476, complete genome7e-72280BLASTN svgBLASTP svg
NC_005956:818000*81800084009922100Bartonella henselae str. Houston-1, complete genome1e-33153BLASTN svgBLASTP svg
NC_012846:986877986877102533738461Bartonella grahamii as4aup, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_012846:19521781952178197441022233Bartonella grahamii as4aup, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_012846:17784431778443180309924657Bartonella grahamii as4aup, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_007205:22153922153924436122823Candidatus Pelagibacter ubique HTCC1062, complete genome8e-0763.9BLASTN svgBLASTP svg