Some Help

Query: NC_010161:1914000 Bartonella tribocorum CIP 105476, complete genome

Start: 1914000, End: 1938268, Length: 24269

Host Lineage: Bartonella tribocorum; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This organism was isolated from the blood of wild rats and from fleas obtained from wild rats. Transmission of these organisms is often through an insect vector. Once in a host, this intracellular pathogen is internalized by an actin-dependent mechanism, and primarily targets endothelial cells, although other cells can be infected. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells. This organism is genetically related to Bartonella elizabethae which was isolated from a case of endocarditis in a human.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_010161:13243811324381135291528535Bartonella tribocorum CIP 105476, complete genome010190BLASTN svgBLASTP svg
NC_010161:19496371949637198084231206Bartonella tribocorum CIP 105476, complete genome07081BLASTN svgBLASTP svg
NC_012846:1837924*1837924187467336750Bartonella grahamii as4aup, complete genome04962BLASTN svgBLASTP svg
NC_005955:1205836*1205836122877522940Bartonella quintana str. Toulouse, complete genome01530BLASTN svgBLASTP svg
NC_005956:1455496*1455496147609920604Bartonella henselae str. Houston-1, complete genome01128BLASTN svgBLASTP svg
NC_020301:669000*66900071117642177Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genome0666BLASTN svgBLASTP svg
NC_007759:1028977*1028977107559946623Syntrophus aciditrophicus SB, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_014932:10844221084422110853724116Bartonella clarridgeiae 73, complete genome5e-0867.9BLASTN svgBLASTP svg
NC_007626:4135961*4135961417095634996Magnetospirillum magneticum AMB-1, complete genome5e-0867.9BLASTN svgBLASTP svg
NC_010161:25482542548254257609927846Bartonella tribocorum CIP 105476, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_005956:818000*81800084009922100Bartonella henselae str. Houston-1, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_020300:12745811274581129336318783Bartonella australis Aust/NH1, complete genome7e-0763.9BLASTN svgBLASTP svg