Pre_GI: BLASTP Hits

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Query: NC_010161:2155500:2171501 Bartonella tribocorum CIP 105476, complete genome

Start: 2171501, End: 2174911, Length: 3411

Host Lineage: Bartonella tribocorum; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This organism was isolated from the blood of wild rats and from fleas obtained from wild rats. Transmission of these organisms is often through an insect vector. Once in a host, this intracellular pathogen is internalized by an actin-dependent mechanism, and primarily targets endothelial cells, although other cells can be infected. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells. This organism is genetically related to Bartonella elizabethae which was isolated from a case of endocarditis in a human.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012846:2004711:2012361201236120142441884Bartonella grahamii as4aup, complete genomephage related helicase0784
NC_005956:1648000:1658982165898216617412760Bartonella henselae str. Houston-1, complete genomephage related protein0746
NC_014932:1314881:1342912134291213449122001Bartonella clarridgeiae 73, complete genomehypothetical protein0687
NC_008783:177161:1936551936551960212367Bartonella bacilliformis KC583, complete genomeputative DNA primase/helicase0684
NC_011770:2690501:2706147270614727079761830Pseudomonas aeruginosa LESB58, complete genomehypothetical protein3e-77291
NC_011601:717072:7331137331137349931881Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomereplication protein7e-73276
NC_014228:3282500:3320813332081333227081896Xenorhabdus nematophila ATCC 19061, complete genomehypothetical protein5e-73276
NC_006905:368942:3853423853423872221881Salmonella enterica subsp. enterica serovar Choleraesuis strhypothetical protein4e-72274
NC_012125:1330066:1347049134704913489291881Salmonella enterica subsp. enterica serovar Paratyphi C strainhypothetical protein2e-71271
NC_011094:593100:6122036122036140351833Salmonella enterica subsp. enterica serovar Schwarzengrund strgp613e-71271
NC_012856:3615550:3635551363555136373441794Ralstonia pickettii 12D chromosome 1, complete genomehypothetical protein2e-67258
NC_002927:3716894:374834037483403749281942Bordetella bronchiseptica RB50, complete genomephage-related hypothetical protein1e-36156
NC_002927:2338549:235034723503472351288942Bordetella bronchiseptica RB50, complete genomephage-related hypothetical protein1e-36156
NC_010002:2110953:212602521260252126996972Delftia acidovorans SPH-1, complete genomephage-related hypothetical protein3e-27125
NC_002947:2589951:2591620259162025932541635Pseudomonas putida KT2440, complete genomeDNA primase/helicase1e-1896.7
NC_014834:3130715:3172458317245831740831626Rhodopseudomonas palustris DX-1 chromosome, complete genomeDNA primase2e-1585.1
NC_014307:233045:2474232474232495462124Ralstonia solanacearum CFBP2957 chromosome, complete genometoprim domain protein4e-1377.8
NC_009937:4122652:4129516412951641311711656Azorhizobium caulinodans ORS 571, complete genomeDNA primase2e-1275.9
NC_002978:549454:5641755641755662232049Wolbachia endosymbiont of Drosophila melanogaster, complete genomeregulatory protein RepA, putative4e-1274.7
NC_010981:1371265:1390240139024013923992160Wolbachia pipientis, complete genomeputative phage related protein1e-1173.2
NC_012416:1079661:1111634111163411138292196Wolbachia sp. wRi, complete genomeregulatory protein RepA, putative9e-1170.1
NC_012416:573202:6051756051756073702196Wolbachia sp. wRi, complete genomeregulatory protein RepA, putative9e-1170.1
NC_014311:198542:2200012200012222802280Ralstonia solanacearum PSI07 chromosome, complete genomeDNA primase, phage/plasmid6e-1067.4
NC_016944:1621575:1641139164113916427731635Vibrio cholerae IEC224 chromosome I, complete sequenceDNA primase/helicase8e-1067
NC_014006:994500:9945869945869960341449Sphingobium japonicum UT26S chromosome 1, complete genomeputative phage DNA primase/helicase1e-0966.2
NC_007645:5801295:5801295580129558035712277Hahella chejuensis KCTC 2396, complete genomepredicted ATPase3e-0965.1
NC_010725:3273261:3295654329565432966941041Methylobacterium populi BJ001, complete genomehypothetical protein4e-0964.7
NC_010981:314745:3426993426993449612263Wolbachia pipientis, complete genome5e-0964.3
NC_010981:242500:2692092692092714562248Wolbachia pipientis, complete genome6e-0964.3
NC_003295:856775:8796328796328819292298Ralstonia solanacearum GMI1000, complete genomehypothetical protein8e-0963.5
NC_009668:445134:5043265043265053691044Ochrobactrum anthropi ATCC 49188 chromosome 2, complete sequencehypothetical protein1e-0863.2
NC_004463:9087290:9089524908952490905911068Bradyrhizobium japonicum USDA 110, complete genomehypothetical protein7e-0860.5
NC_009720:622262:6461966461966472331038Xanthobacter autotrophicus Py2, complete genomehypothetical protein1e-0759.7
NC_015422:2078618:2103438210343821057382301Alicycliphilus denitrificans K601 chromosome, complete genomephage/plasmid primase, P4 family2e-0759.3
NC_014310:1822751:186755518675551868433879Ralstonia solanacearum PSI07 megaplasmid, complete sequence2e-0758.9
NC_010510:310938:3123563123563134021047Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, completehypothetical protein2e-0758.9
NC_011365:1171536:1171536117153611725821047Gluconacetobacter diazotrophicus PAl 5 chromosome, complete genomehypothetical protein5e-0757.8
NC_014217:2987450:2992130299213029931641035Starkeya novella DSM 506 chromosome, complete genomehypothetical protein6e-0757.4
NC_010125:2884762:2888834288883428899161083Gluconacetobacter diazotrophicus PAl 5, complete genomehypothetical protein6e-0757.4
NC_015580:293803:3337553337553347981044Novosphingobium sp. PP1Y, complete genomehypothetical protein8e-0653.5
NC_015186:2931000:2931030293103029320911062Acidiphilium multivorum AIU301, complete genomehypothetical protein8e-0653.5