Pre_GI: BLASTP Hits

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Query: NC_010161:2155500:2155674 Bartonella tribocorum CIP 105476, complete genome

Start: 2155674, End: 2156012, Length: 339

Host Lineage: Bartonella tribocorum; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This organism was isolated from the blood of wild rats and from fleas obtained from wild rats. Transmission of these organisms is often through an insect vector. Once in a host, this intracellular pathogen is internalized by an actin-dependent mechanism, and primarily targets endothelial cells, although other cells can be infected. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells. This organism is genetically related to Bartonella elizabethae which was isolated from a case of endocarditis in a human.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010172:3894652:390066039006603901067408Methylobacterium extorquens PA1, complete genomehelix-turn-helix domain protein6e-0959.3
NC_002678:5060670:508434650843465084993648Mesorhizobium loti MAFF303099, complete genomehypothetical protein2e-0651.2
NC_007626:2354260:236366923636692364274606Magnetospirillum magneticum AMB-1, complete genomePredicted transcriptional regulator1e-1168.2
NC_007626:2204767:225814622581462258673528Magnetospirillum magneticum AMB-1, complete genomePredicted transcriptional regulator3e-1167.4
NC_010161:2100500:210348121034812103873393Bartonella tribocorum CIP 105476, complete genometranscriptional regulator9e-25112
NC_005956:1616804:163224416322441632570327Bartonella henselae str. Houston-1, complete genomeTranscriptional regulator6e-1062.8
NC_005956:1616804:162637416263741626760387Bartonella henselae str. Houston-1, complete genomeTranscriptional regulator7e-28122
NC_010161:2100500:211674621167462116904159Bartonella tribocorum CIP 105476, complete genometranscriptional regulator1e-0755.1
NC_010161:2100500:211331221133122113719408Bartonella tribocorum CIP 105476, complete genometranscriptional regulator7e-1992.4
NC_010161:2100500:211866821186682119057390Bartonella tribocorum CIP 105476, complete genometranscriptional regulator3e-21100
NC_010338:1216385:121685712168571217219363Caulobacter sp. K31, complete genometranscriptional regulator, XRE family3e-0960.5
NC_008686:2417000:242008924200892420415327Paracoccus denitrificans PD1222 chromosome 1, complete sequencetranscriptional regulator, XRE family1e-0755.1
NC_011894:6382636:638604663860466386411366Methylobacterium nodulans ORS 2060, complete genometranscriptional regulator, XRE family1e-1168.6
NC_008347:1636660:164813516481351648545411Maricaulis maris MCS10, complete genometranscriptional regulator, XRE family9e-0648.9
NC_010338:359940:375896375896376411516Caulobacter sp. K31, complete genometranscriptional regulator, XRE family2e-0961.2
NC_010725:3992948:400874240087424009149408Methylobacterium populi BJ001, complete genometranscriptional regulator, XRE family3e-1167.4
NC_011757:5048714:508686850868685087272405Methylobacterium chloromethanicum CM4, complete genometranscriptional regulator, XRE family1e-0962
NC_012988:731790:743625743625743960336Methylobacterium extorquens DM4, complete genomeXRE family transcriptional regulator4e-0753.1
NC_010511:2703684:272100827210082721412405Methylobacterium sp. 4-46 chromosome, complete genomeXRE family transcriptional regulator1e-1065.1
NC_012988:731790:744283744283744759477Methylobacterium extorquens DM4, complete genomeXRE family transcriptional regulator8e-0958.9