Pre_GI: BLASTP Hits

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Query: NC_010161:205500:230443 Bartonella tribocorum CIP 105476, complete genome

Start: 230443, End: 231027, Length: 585

Host Lineage: Bartonella tribocorum; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This organism was isolated from the blood of wild rats and from fleas obtained from wild rats. Transmission of these organisms is often through an insect vector. Once in a host, this intracellular pathogen is internalized by an actin-dependent mechanism, and primarily targets endothelial cells, although other cells can be infected. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells. This organism is genetically related to Bartonella elizabethae which was isolated from a case of endocarditis in a human.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_005955:173436:197530197530198123594Bartonella quintana str. Toulouse, complete genomenicotinic acid mononucleotide adenyltransferase9e-89325
NC_020301:174467:204450204450205043594Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genomenicotinic acid mononucleotide adenylyltransferase1e-85315
NC_014932:1232346:123333212333321233958627Bartonella clarridgeiae 73, complete genomenicotinate-nucleotide adenylyltransferase5e-77286
NC_003317:190975:215596215596216270675Brucella melitensis 16M chromosome I, complete sequencenicotinic acid mononucleotide adenyltransferase2e-54211
NC_014923:1249267:127097212709721271559588Mesorhizobium ciceri biovar biserrulae WSM1271 chromosome, completenicotinate (nicotinamide) nucleotide adenylyltransferase4e-52204
NC_003047:3419212:344471434447143445280567Sinorhizobium meliloti 1021, complete genomenicotinic acid mononucleotide adenyltransferase3e-51201
NC_008380:4968492:498741349874134988012600Rhizobium leguminosarum bv. viciae 3841, complete genomeputative nicotinate-nucleotide adenylyltransferase3e-50197
NC_016078:3130573:315219231521923152827636Pelagibacterium halotolerans B2 chromosome, complete genomenicotinate-nucleotide adenylyltransferase, NadD family2e-45181
NC_006677:1255079:125745512574551258042588Gluconobacter oxydans 621H, complete genomenicotinic acid mononucleotide adenyltransferase8e-32136
NC_006832:475290:490392490392490976585Ehrlichia ruminantium str. Welgevonden, complete genomeProbable nicotinate-nucleotide adenylyltransferase1e-22106
NC_004663:2509433:252608725260872526695609Bacteroides thetaiotaomicron VPI-5482, complete genomenicotinic acid mononucleotide adenyltransferase3e-1788.6
NC_016609:7819243:782683178268317827403573Niastella koreensis GR20-10 chromosome, complete genomenicotinate-nucleotide adenylyltransferase2e-1685.5
NC_015930:821342:837763837763838350588Lactococcus garvieae ATCC 49156, complete genomenicotinate-nucleotide adenylyltransferase3e-1684.7
NC_007205:221539:224851224851225393543Candidatus Pelagibacter ubique HTCC1062, complete genomeprobable nicotinate-nucleotide adenylyltransferase4e-1684.7
NC_015846:493388:494170494170494751582Capnocytophaga canimorsus Cc5 chromosome, complete genomeNicotinate mononucleotide adenylyltransferase6e-1477.4
NC_015510:4251553:425402942540294254643615Haliscomenobacter hydrossis DSM 1100 chromosome, complete genomenicotinate-nucleotide adenylyltransferase1e-1375.9
NC_018644:137755:173709173709174266558Alpha proteobacterium HIMB59 chromosome, complete genomecytidyltransferase-like enzyme6e-1373.9
NC_013501:777947:778793778793779392600Rhodothermus marinus DSM 4252, complete genomenicotinate (nicotinamide) nucleotide adenylyltransferase1e-1272.8
NC_014166:401815:406442406442406978537Arcobacter nitrofigilis DSM 7299 chromosome, complete genomenicotinate (nicotinamide) nucleotide adenylyltransferase2e-1168.9
NC_011979:646518:675652675652676302651Geobacter sp. FRC-32, complete genomenicotinate (nicotinamide) nucleotide adenylyltransferase2e-1168.6
NC_014623:5661108:568681256868125687390579Stigmatella aurantiaca DW4/3-1 chromosome, complete genomenicotinate-nucleotide adenylyltransferase2e-1065.5
NC_011653:748844:770805770805771431627Thermosipho africanus TCF52B, complete genomenicotinate (nicotinamide) nucleotide adenylyltransferase9e-1063.5
NC_016012:396910:402569402569403180612Candidatus Arthromitus sp. SFB-rat-Yit, complete genomenicotinic acid mononucleotide adenylyltransferase6e-0960.5
NC_020134:1328302:132963413296341330236603Clostridium stercorarium subsp. stercorarium DSM 8532, completenicotinate-nucleotide adenylyltransferase NadD9e-0960.1
NC_004917:340997:340997340997341653657Helicobacter hepaticus ATCC 51449, complete genomehypothetical protein2e-0859.3
NC_011899:1437981:143976914397691440383615Halothermothrix orenii H 168, complete genomenicotinate (nicotinamide) nucleotide adenylyltransferase2e-0858.9
NC_015873:2260048:228017122801712280812642Megasphaera elsdenii DSM 20460, complete genomeprobable nicotinate-nucleotide adenylyltransferase3e-0858.2
NC_014752:324832:324832324832325440609Neisseria lactamica ST-640, complete genomenicotinate-nucleotide adenylyltransferase4e-0857.8
NC_018515:4196409:420073242007324201364633Desulfosporosinus meridiei DSM 13257 chromosome, complete genomenicotinate/nicotinamide nucleotide adenylyltransferase7e-0857
NC_013851:2441407:245782624578262458500675Allochromatium vinosum DSM 180 chromosome, complete genomenicotinate (nicotinamide) nucleotide adenylyltransferase1e-0755.8
NC_015499:1403447:140758514075851408184600Thermodesulfobium narugense DSM 14796 chromosome, complete genomenicotinate-nucleotide adenylyltransferase2e-0755.5
NC_009802:1525144:152622215262221527103882Campylobacter concisus 13826, complete genomegerC2 protein3e-0754.7
NC_008710:819389:828552828552829124573Borrelia turicatae 91E135, complete genomenicotinamide-nucleotide adenylyltransferase6e-0753.9
NC_017095:166896:174832174832175497666Fervidobacterium pennivorans DSM 9078 chromosome, complete genomenicotinate/nicotinamide nucleotide adenylyltransferase7e-0753.9
NC_014220:1732254:175182717518271752456630Syntrophothermus lipocalidus DSM 12680 chromosome, complete genomenicotinate (nicotinamide) nucleotide adenylyltransferase8e-0753.5