Pre_GI: BLASTP Hits

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Query: NC_010161:205500:224710 Bartonella tribocorum CIP 105476, complete genome

Start: 224710, End: 226020, Length: 1311

Host Lineage: Bartonella tribocorum; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This organism was isolated from the blood of wild rats and from fleas obtained from wild rats. Transmission of these organisms is often through an insect vector. Once in a host, this intracellular pathogen is internalized by an actin-dependent mechanism, and primarily targets endothelial cells, although other cells can be infected. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells. This organism is genetically related to Bartonella elizabethae which was isolated from a case of endocarditis in a human.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_005956:196976:2161492161492174591311Bartonella henselae str. Houston-1, complete genomeExopolyphosphatase0653
NC_016078:913713:9326779326779338761200Pelagibacterium halotolerans B2 chromosome, complete genomeexopolyphosphatase1e-95350
NC_007626:4135961:4160694416069441618421149Magnetospirillum magneticum AMB-1, complete genomeExopolyphosphatase5e-72271
NC_005955:173436:1918001918001930971298Bartonella quintana str. Toulouse, complete genome1e-35151
NC_009483:2489000:249491924949192495830912Geobacter uraniireducens Rf4 chromosome, complete genomePpx/GppA phosphatase8e-25115
NC_009922:2850320:285708328570832858036954Alkaliphilus oremlandii OhILAs, complete genomePpx/GppA phosphatase1e-24114
NC_015589:2941953:2959009295900929605321524Desulfotomaculum ruminis DSM 2154 chromosome, complete genomePpx/GppA phosphatase1e-24114
NC_015185:592598:607387607387608310924Desulfurobacterium thermolithotrophum DSM 11699 chromosome,Ppx/GppA phosphatase1e-23111
NC_010842:425854:4458244458244474251602Leptospira biflexa serovar Patoc strain 'Patoc 1 (Ames)' chromosomeGuanosine-5'-triphosphate, 3'-diphosphatepyrophosphatase4e-23109
NC_009482:619467:6212376212376229221686Synechococcus sp. RCC307 chromosome, complete genomeexopolyphosphatase4e-22106
NC_011979:3045952:306150430615043062409906Geobacter sp. FRC-32, complete genomePpx/GppA phosphatase1e-21104
NC_018750:3141196:315449031544903155404915Streptomyces venezuelae ATCC 10712, complete genomeExopolyphosphatase8e-21101
NC_012590:1004816:101121210112121012174963Corynebacterium aurimucosum ATCC 700975, complete genomeExopolyphosphatase3e-2099.8
NC_014538:2158131:218504321850432185948906Thermoanaerobacter sp. X513 chromosome, complete genomePpx/GppA phosphatase1e-1998.2
NC_015957:9801884:980365998036599804618960Streptomyces violaceusniger Tu 4113 chromosome, complete genomePpx/GppA phosphatase8e-1995.1
NC_014614:356746:395287395287396201915Clostridium sticklandii, complete genomeputative exopolyphosphatase2e-1894
NC_014752:834616:8346168346168361241509Neisseria lactamica ST-640, complete genomeexopolyphosphatase2e-1790.9
NC_017515:800000:8024478024478039551509Neisseria meningitidis M04-240196 chromosome, complete genomeexopolyphosphatase6e-1789
NC_014152:191200:205611205611206567957Thermincola sp. JR, complete genomePpx/GppA phosphatase6e-1789
NC_011060:459615:4909314909314924901560Pelodictyon phaeoclathratiforme BU-1, complete genomePpx/GppA phosphatase2e-1687.4
NC_004917:946550:9608859608859623571473Helicobacter hepaticus ATCC 51449, complete genomeexopolyphosphatase2e-1687
NC_012623:2369671:2382457238245723837131257Sulfolobus islandicus Y.N.15.51 chromosome, complete genomePpx/GppA phosphatase3e-1686.7
NC_012622:327821:3278213278213290771257Sulfolobus islandicus Y.G.57.14 chromosome, complete genomePpx/GppA phosphatase3e-1686.7
NC_008321:458811:458811458811459737927Shewanella sp. MR-4, complete genomePpx/GppA phosphatase5e-1686.3
NC_017276:320000:3252013252013264571257Sulfolobus islandicus REY15A chromosome, complete genomePpx/GppA phosphatase6e-1685.9
NC_015519:197836:200519200519201436918Tepidanaerobacter sp. Re1 chromosome, complete genomePpx/GppA phosphatase8e-1685.5
NC_015144:2053969:206578720657872066671885Weeksella virosa DSM 16922 chromosome, complete genomePpx/GppA phosphatase7e-1685.5
NC_014958:3393855:3393855339385533953511497Deinococcus maricopensis DSM 21211 chromosome, complete genomePpx/GppA phosphatase6e-1685.5
NC_013769:316789:3213003213003225561257Sulfolobus islandicus L.D.8.5 chromosome, complete genomePpx/GppA phosphatase9e-1685.1
NC_012704:652589:6637526637526653381587Corynebacterium kroppenstedtii DSM 44385, complete genomeExopolyphosphatase1e-1584.7
NC_007181:1818500:1832110183211018333451236Sulfolobus acidocaldarius DSM 639, complete genomehypothetical protein2e-1584
NC_009802:931129:947801947801948682882Campylobacter concisus 13826, complete genomeWalN protein2e-1584
NC_009663:2056166:2057254205725420587771524Sulfurovum sp. NBC37-1, complete genomeguanosine pentaphosphate phosphohydrolase8e-1582
NC_017187:1683619:1708467170846717099361470Arcobacter butzleri ED-1, complete genomeguanosine pentaphosphate phosphohydrolase5e-1479.3
NC_009850:1822239:1824917182491718263861470Arcobacter butzleri RM4018, complete genomeguanosine pentaphosphate phosphohydrolase (gppA)5e-1479.3
NC_009665:4675289:469563846956384696564927Shewanella baltica OS185 chromosome, complete genomePpx/GppA phosphatase7e-1479
NC_013960:2366910:2368637236863723701451509Nitrosococcus halophilus Nc4 chromosome, complete genomeGuanosine-5'-triphosphate,3'-diphosphate diphosphatase1e-1377.8
NC_009714:671897:6921166921166935641449Campylobacter hominis ATCC BAA-381, complete genomephosphatase3e-1376.6
NC_013093:737737:749617749617750579963Actinosynnema mirum DSM 43827, complete genomePpx/GppA phosphatase4e-1376.6
NC_015978:352478:376639376639377568930Lactobacillus sanfranciscensis TMW 1.1304 chromosome, completehypothetical protein5e-1375.9
NC_014377:112992:114645114645115556912Thermosediminibacter oceani DSM 16646 chromosome, complete genomePpx/GppA phosphatase2e-1273.6
NC_015556:515641:5349705349705364751506Pseudomonas fulva 12-X chromosome, complete genomePpx/GppA phosphatase4e-1273.2
NC_020063:1194000:1209930120993012114711542Enterobacteriaceae bacterium strain FGI 57, complete genomeexopolyphosphatase3e-1273.2
NC_011663:4579777:460070846007084601634927Shewanella baltica OS223 chromosome, complete genomePpx/GppA phosphatase4e-1272.8
NC_013194:69634:6963469634711721539Candidatus Accumulibacter phosphatis clade IIA str. UW-1, completePpx/GppA phosphatase7e-1272
NC_008390:1293823:1297609129760912991231515Burkholderia cepacia AMMD chromosome 1, complete sequencePpx/GppA phosphatase2e-1170.9
NC_009052:2107692:2126007212600721275691563Shewanella baltica OS155, complete genomePpx/GppA phosphatase2e-1170.9
NC_003228:3085793:310992231099223110836915Bacteroides fragilis NCTC 9343, complete genomeputative phosphatase2e-1170.5
NC_020541:2769419:2771597277159727731141518Rhodanobacter sp. 2APBS1, complete genomeexopolyphosphatase3e-1170.1
NC_011896:332939:336321336321337274954Mycobacterium leprae Br4923, complete genomehypothetical protein6e-1169.3
NC_002677:332923:336305336305337258954Mycobacterium leprae TN, complete genomehypothetical protein6e-1169.3
NC_009256:1365500:1365691136569113672051515Burkholderia vietnamiensis G4 chromosome 1, complete sequencePpx/GppA phosphatase5e-1169.3
NC_015321:1553590:156771915677191568597879Fluviicola taffensis DSM 16823 chromosome, complete genomePpx/GppA phosphatase8e-1168.6
NC_013282:3216226:3218290321829032198311542Cronobacter turicensis, complete genomeExopolyphosphatase1e-1068.2
NC_012880:3125261:3129740312974031312691530Dickeya dadantii Ech703, complete genomePpx/GppA phosphatase2e-1067.4
NC_016001:1893685:189577818957781896683906Flavobacterium branchiophilum, complete genomeExopolyphosphatase4e-1066.6
NC_015514:3351052:337237733723773373330954Cellulomonas fimi ATCC 484 chromosome, complete genomePpx/GppA phosphatase4e-1066.2
NC_011283:1307173:1326827132682713283591533Klebsiella pneumoniae 342 chromosome, complete genomeexopolyphosphatase5e-1066.2
NC_011601:2806392:2806392280639228079331542Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomeexopolyphosphatase1e-0965.1
NC_015737:2050219:205021920502192051148930Clostridium sp. SY8519, complete genomeexopolyphosphatase2e-0963.9
NC_005085:1269787:1325869132586913273621494Chromobacterium violaceum ATCC 12472, complete genomeexopolyphosphatase1e-0861.6
NC_009515:1409912:145137614513761452290915Methanobrevibacter smithii ATCC 35061, complete genomeexopolyphosphatase, GppA1e-0861.2
NC_007973:2348481:2382819238281923843511533Ralstonia metallidurans CH34 chromosome 1, complete sequencePpx/GppA phosphatase3e-0860.5
NC_006905:2630000:2634375263437526358441470Salmonella enterica subsp. enterica serovar Choleraesuis strexopolyphosphatase3e-0860.1
NC_012559:854507:8545078545078560301524Laribacter hongkongensis HLHK9, complete genomePpx2e-0757.4
NC_008618:1526392:152639215263921527363972Bifidobacterium adolescentis ATCC 15703, complete genomehypothetical protein2e-0654.3
NC_015161:36668:3969339693412581566Deinococcus proteolyticus MRP chromosome, complete genomePpx/GppA phosphatase5e-0652.8
NC_020181:5384015:5404251540425154056751425Enterobacter aerogenes EA1509E, complete genomeExopolyphosphatase9e-0652