Pre_GI: BLASTP Hits

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Query: NC_010161:1949637:1963750 Bartonella tribocorum CIP 105476, complete genome

Start: 1963750, End: 1965729, Length: 1980

Host Lineage: Bartonella tribocorum; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This organism was isolated from the blood of wild rats and from fleas obtained from wild rats. Transmission of these organisms is often through an insect vector. Once in a host, this intracellular pathogen is internalized by an actin-dependent mechanism, and primarily targets endothelial cells, although other cells can be infected. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells. This organism is genetically related to Bartonella elizabethae which was isolated from a case of endocarditis in a human.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010161:2548254:2561926256192625639051980Bartonella tribocorum CIP 105476, complete genometransposase (class III)01315
NC_010161:1324381:1338041133804113400111971Bartonella tribocorum CIP 105476, complete genometransposase (class III)01278
NC_010161:1501758:1515418151541815173881971Bartonella tribocorum CIP 105476, complete genometransposase (class III)01278
NC_020301:853267:8597598597598617321974Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genometransposase (class III)01107
NC_012759:4132527:4132527413252741337861260Escherichia coli BW2952 chromosome, complete genomeTransposase1e-59231
NC_014228:3282500:328529732852973286259963Xenorhabdus nematophila ATCC 19061, complete genome7e-31135
NC_014228:3282500:328614432861443286842699Xenorhabdus nematophila ATCC 19061, complete genome4e-1790.5
NC_012759:4132527:413386241338624134518657Escherichia coli BW2952 chromosome, complete genomeTransposase7e-1789.4
NC_014972:2798670:2814211281421128162232013Desulfobulbus propionicus DSM 2032 chromosome, complete genometransposase-like Mu4e-1687
NC_014828:541874:5428405428405447921953Ethanoligenens harbinense YUAN-3 chromosome, complete genomeTransposase-like Mu9e-1582.8
NC_007519:3326918:3326918332691833290442127Desulfovibrio alaskensis G20 chromosome, complete genomebacteriophage transposase A protein2e-1377.8
NC_012796:1600600:1600600160060016026992100Desulfovibrio magneticus RS-1, complete genomehypothetical protein2e-1171.6
NC_002937:1233000:1235666123566612378192154Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough, completebacteriophage transposase A protein, putative2e-1171.2
NC_009659:892272:9091379091379110831947Janthinobacterium sp. Marseille chromosome, complete genomehypothetical protein2e-0861.6
NC_013416:939668:951308951308951565258Aggregatibacter actinomycetemcomitans D11S-1, complete genometransposase4e-0860.5
NC_015172:3160249:3193802319380231958862085Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomeTransposase-like Mu5e-0757
NC_015172:515557:5230675230675251512085Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomeTransposase-like Mu5e-0757
NC_015172:2986867:3019582301958230216662085Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomeTransposase-like Mu5e-0757
NC_015172:2628128:2665055266505526671392085Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomeTransposase-like Mu5e-0757
NC_015386:107000:108075108075108956882Treponema succinifaciens DSM 2489 plasmid pTRESU01, completeIntegrase catalytic region6e-0756.6
NC_015848:2381148:239781823978182398645828Mycobacterium canettii CIPT 140010059, complete genomeintegrase catalytic subunit3e-0653.9
NC_015848:2381148:240044124004412401268828Mycobacterium canettii CIPT 140010059, complete genomeintegrase catalytic subunit3e-0653.9