Pre_GI: BLASTP Hits

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Query: NC_010161:1949637:1951394 Bartonella tribocorum CIP 105476, complete genome

Start: 1951394, End: 1952443, Length: 1050

Host Lineage: Bartonella tribocorum; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This organism was isolated from the blood of wild rats and from fleas obtained from wild rats. Transmission of these organisms is often through an insect vector. Once in a host, this intracellular pathogen is internalized by an actin-dependent mechanism, and primarily targets endothelial cells, although other cells can be infected. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells. This organism is genetically related to Bartonella elizabethae which was isolated from a case of endocarditis in a human.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010161:1501758:1503074150307415041231050Bartonella tribocorum CIP 105476, complete genomehypothetical protein0714
NC_010161:1324381:1325697132569713267461050Bartonella tribocorum CIP 105476, complete genomehypothetical protein0714
NC_010161:2548254:2549570254957025506191050Bartonella tribocorum CIP 105476, complete genomehypothetical protein0714
NC_020301:853267:8728408728408739071068Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genomehypothetical protein0632
NC_016002:1741109:175357517535751754540966Pseudogulbenkiania sp. NH8B, complete genomeMu-like prophage I protein9e-30131
NC_016002:2179969:219192621919262192891966Pseudogulbenkiania sp. NH8B, complete genomeMu-like prophage I protein9e-30131
NC_018604:305957:332400332400333395996Brachyspira pilosicoli WesB complete genomeputative Mu-like prophage I protein9e-25114
NC_017243:58000:7937779377803781002Brachyspira intermedia PWS/A chromosome, complete genomeMu-like prophage I protein1e-23110
NC_012751:1988280:200200520020052002787783Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum), completeMu-like prophage I protein2e-22107
NC_014034:3111981:3114846311484631159461101Rhodobacter capsulatus SB1003 chromosome, complete genomehypothetical protein3e-1892.8
NC_008014:112000:1219831219831231221140Lawsonia intracellularis PHE/MN1-00 plasmid 3, complete sequencehypothetical protein8e-1684.7
NC_015172:515557:5356765356765367311056Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomeMu-like prophage I protein2e-1583.6
NC_015172:2986867:3008002300800230090571056Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomeMu-like prophage I protein2e-1583.6
NC_015172:3160249:3182222318222231832771056Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomeMu-like prophage I protein2e-1583.6
NC_015172:2628128:2653475265347526545301056Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomeMu-like prophage I protein2e-1583.6
NC_015388:1678000:1690390169039016914931104Desulfobacca acetoxidans DSM 11109 chromosome, complete genomeMu-like prophage I protein6e-1478.6
NC_015424:1987964:1995148199514819963681221Aeromonas veronii B565 chromosome, complete genomeI protein2e-1170.5
NC_000907:1568867:1577768157776815788351068Haemophilus influenzae Rd KW20, complete genomeI protein7e-1065.1
NC_009714:224325:241232241232241972741Campylobacter hominis ATCC BAA-381, complete genomehypothetical protein4e-0962.8
NC_014228:3282500:3299927329992733011441218Xenorhabdus nematophila ATCC 19061, complete genomeputative protease protein7e-0755.1
NC_009850:1651410:166931016693101670110801Arcobacter butzleri RM4018, complete genomeMu-like prophage I protein, putative9e-0754.7
NC_009256:1365500:137273613727361373422687Burkholderia vietnamiensis G4 chromosome 1, complete sequenceMu-like prophage I protein-like9e-0754.7